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Objective To investigate the effect of atorvastatin intensive therapy on cardiac function and lipoprotein phospho‐lipase A2 (Lp‐PLA2) in patients with hypertension complicated with ST segment elevation acute myocardial infarction .Methods Totally 78 patients with hypertension complicated with ST segment elevation acute myocardial infarction from June 2014 to April 2016 in our hospital patients ,according to the random number table method divided into observation group (atorvastatin therapy ) and control group (routine treatment) .The changes of blood pressure ,blood lipid ,Lp‐PLA2 ,cardiac function of two groups were compared before and after treatment .Results Before treatment ,there was no significant difference in blood pressure and blood lipid between the two groups (P>0 .05) .After treatment ,the two groups of patients with SBP ,DBP ,LDL‐C significantly decreased , HDL‐C significantly increased ,and compared with the control group ,the SBP ,HDL‐C ,LDL‐C in the observation group were signif‐icantly different (P0 .05) . After treatment ,the two groups of patients with Lp‐PLA2 were significantly reduced ,and the observation group was significantly greater (P0 .05) .Af‐ter treatment ,the observation group of patients with LVESD ,LVEDD significantly decreased ,LVEF ,CO ,CI significantly in‐creased ,compared with the control group ,the difference was statistically significant (P<0 .05) .Conclusion Atorvastatin intensive therapy can significantly reduce high blood pressure acute ST segment elevated blood pressure and Lp‐PLA2 levels in patients with acute myocardial infarction and improve cardiac function ,worthy of promotion .
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<p><b>OBJECTIVE</b>To assess the stiffness and thickness of the plantar fascia using shear wave elastography (SWE) in healthy volunteers of different ages and in patients with plantar fasciitis.</p><p><b>METHODS</b>The bilateral feet of 30 healthy volunteers and 23 patients with plantar fasciitis were examined with SWE. The plantar fascia thickness and elasticity modulus value were measured at the insertion of the calcaneus and at 1 cm from the insertion.</p><p><b>RESULTS</b>The elderly volunteers had a significantly greater plantar fascia thickness measured using conventional ultrasound (P=0.005) and a significantly lower elasticity modulus value than the young volunteers (P=0.000). The patients with fasciitis had a significantly greater plantar fascia thickness (P=0.001) and a lower elasticity modulus value than the elderly volunteers (P=0.000). The elasticity modulus value was significantly lower at the calcaneus insertion than at 1 cm from the insertion in patients with fasciitis (P=0.000) but showed no significantly difference between the two points in the elderly or young volunteers (P=0.172, P=0.126).</p><p><b>CONCLUSION</b>SWE allows quantitative assessment of the stiffness of the plantar fascia, which decreases with aging and in patients with plantar fasciitis.</p>
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Adult , Aged , Female , Humans , Male , Middle Aged , Case-Control Studies , Elasticity Imaging Techniques , Fascia , Diagnostic Imaging , Fasciitis, Plantar , Diagnostic ImagingABSTRACT
Cervical spondylotic radiculopathy is a commonly encountered and frequently occurring disease. Traditional Chinese osteopathic manipulations may have better therapeutic efficacy than that of other methods in treating patients with cervical spondylotic radiculopathy.
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Objective To study the relationship between serum fibrosis parameters levels and chronic viral hepatitis B patients.Methods Radioimmunoassay and chemiluminescence were used to test the levels of hyaluronic acid(HA),collagen type Ⅳ(Ⅳ-C),laminin(LN) and procollagen type Ⅲ(PC Ⅲ) in 146 cases of chronic hepatitis B and 40 of normal controls,and the relationship with clinical parameters of liver function were analyzed.Results The levels of HA,Ⅳ-C,LN,PC Ⅲ in chronic hepatitis B patients were higher than those of normal control group (P ＜0.05 or P ＜ 0.01),there were statistical differen in different course of disease (P ＜ 0.05 or P ＜ 0.01) ; The levels of serum Ⅳ-C and PCⅢ had positive correlation with plasma PT,the same to HA with TBil and PCⅢ with ALT;The levels of HA,Ⅳ-C and LN had negative correlation with Alb,the same to LN with CHE.Conclusion The levels of HA,Ⅳ-C,LN and PC Ⅲ in chronic hepatitis B patients may reflect the situations of hepatic fibrosis and the degrees of liver function damage.
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Pain due to chronic soft tissue injury of the neck and shoulder is a commonly encountered and frequently occurring condition. Traditional Chinese medicine is a common course of treatment for soft tissue injury and may have better therapeutic effects than biomedical options.
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Objective To explore the effects of adefovir velocimeter(ADV) combined with Thymopeptides α1 in treatment of patients with chronic hepatitis B (CHB) against hepatitis B virus (HBV). Methods 67 cases of CHB of positive HBeAg were divided into coupling group and single group. 34 cases of coupling group, after being treated for 26 weeks with thymopeptides α1 and ADV,continued to be treated 52 weeks with ADV. 33 cases of single group were treated for 52 weeks with ADV alone. Alanine aminotransferase periodically (ALT), total bilirubin, HBV DNA,HBeAg,anti-HBe were detected at regular intervals. Efficacy were evaluated after finishing the treatment. Results The liver function were both improved obviously in two groups (P ＞ 0. 05). Frequencen of seroconversio of HBeAg/anti-HBe and negative conversion ratio of HBV DNA were much higher in coupling group than that in single group(P ＜ 0. 05). Conclusions The effects were better with Thymopeptides α1 and ADV than that with single ADV. Coupling Thymopeptides α1 and ADV could help to resist and remove HBV.
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Objective To explore the clinical significance of blood serum AFP determination in gravis type viral hepatitis. Methods The level of blood serum AFP was determined by radioimmunoassay in 85 eases of gravis type viral hepatitis, and its change was observed in a dynamic state. Results The abnormality rate of AFP was 83. 6% in the patients of gravis type viral hepatitis. The abnormality rate of AFP in acute gravis type viral hepatitis was significantly lower than that in suhacute severe hepatitis and chronic severe hepatitis(P < 0.01). The survival rate in the team with high level of AFP was significantly higher than that of teams with normal or low level of AFP(P <0.01～0.05) in the patients of gravis type viral hepatitis. The blood serum AFP level in the survivors was significant-ly higher than that of the death in the patients of gravis type viral hepatitis(P <0.01). Conclusions The blood ser-um AFP determination in gravis type viral hepatitis,can be used as a sensitive index for prognosis. A high level of AFP indicates that the hepatic cells regeneration is active and the prognosis is relatively better.
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tralateral parietal lobe. Conclusions CIMT can improve the patients' upper-limb function effectively. The constraint-induced movement of the affected arm during CIMT appears to induce cortical reorganization and compensation as measured by fMRL
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@#Objective To investigate the evidence of cortical reorganization in stroke hemiplegia treated with constraint-induced movement therapy(CIMT)by fMRI.Methods Five patients with chronic stroke were evaluated with the Action Research Arm Test(ARAT).The functional MRI(fMRI)was performed on a 3.0-T MRI with echo-planar imaging.The subjects were required to finish the finger-tapping task and undergo fMRI before and after CIMT.A block design was used for the inspection.Results After CIMT,the function of upper limb(sick side)of patients improved significantly assessed by ARAT(P<0.001),and cortical reorganization was found on fMRI.Conclusion CIMT can improve motor function of upper limb of chronic stroke patients with hemiplegia and induce cortical reorganization as measured by fMRI.