ABSTRACT
Objective To explore the significance of combined detection of procalcitonin(PCT)and C reactive protein(CRP)for clinical use of antibacterial agents in patients with pulmonary disease.Methods 130 cases of patients with pulmonary disease,from October 2012 to October 2014,were selected and randomly dividend into the observation group and control group,65 cases in each group.In the observation group,the utilization of antibacterial agents was decided according to serum levels of PCT and CRP,while in the control group that was based on the white blood cell count.Observation indexes,such as utilization of antibacterial agents, curative efficiency,length of stay and so on,were compared between the two groups after treatment.Results The length of antibac-terial agents use in the observation group[(8.6±0.4)d]was longer than that in the control group[(1 6.2±2.3)d],had statistically significant difference(P 0.05).While compared with the control group,the dual infection rate and length of stay decreased in the observation group,had sta-tistically significant difference(P <0.05).Conclusion Combined detection of PCT and CRP could guide the rational use of antibac-terial agents,effectively prevent the dual infection,and improve clinical curative effect.
ABSTRACT
From July of 1989 to January of 1991,we performed surgical operations on 20 cases with intractable epilepsy.The preoperative localization of epileptogenic foci was based on a comprehensive evaluation of patients'seizure history,scalp EEG,topographic EEG display, cranial electrode recording,CT and neuropsychological investigations.Then,we selected an adequate surgical treatment,including 1 case of hemispherectomy,10 cases of anterior tem- poral lobectomy and 8 cases of extratemporal resection of the epileptogenic focus.Detected by electrocorticography and electrical stimulation monitoring,16 postoperative cases(80%) had seizure free and 4 cases(20%)had a more than 50% reduction in seizure frequency. The localization of epileptogenic foci,and surgical method and effect were discussed in detail. The key of surgical selection is to exactly localize epileptogenic foci with a comprehensive evaluation of various recordings and studies.The intracranial electrode recording is important for the localization of an epileptogenic focus.