ABSTRACT
Objective The aim of this study is to explore epidemic characteristics of HIV/AIDS by different route of transmission during 2011—2014 in Huzhou City,then to provide a scientific basis for the prevention and control of HIV. Methods The epidemiological case data of HIV/AIDS from 2011 to 2014 were collected in Huzhou City by China information system for disease control and prevention.Descriptive epidemiological methods were used for analysis.Results A total of 436 cases with HIV/AIDS were reported during 2011—2014 in Huzhou City,and the number of HIV/AIDS reports increased year by year.The main route of transmission include heterosexual contact,which was accounted for 56.65%.MSM transmission was accounted for 38.53%,and injection drug transmission was accounted for 3.90%.Mother to child transmission was 1 case and blood transfusion /blood products transmission were 3 cases,which accounting for 0.92%.The constituent ratio of injecting drug patients,mother to child transmission or blood transfusion /blood products patients presented declining trend (P <0.05).Patients who were infected through heterosexual contact mainly were 30 to <60 years of age (68.83%),junior middle school or below education level (80.97%),married (61.94%).Patients who were infected through MSMmainly were 15 to <45 years of age (76.19%),high school or higher education (47.62%), unmarried (51.19%),household registration of Huzhou City (52.98%).Patients who were infected through injection <br> drug mainly were 30 to <45 years of age (70.59%),primary school or lower education level (82.35%),unmarried (47.06%),household registration of other province (94.12%).Most cases were detected HIV positive through clinical tests,which accounting for 51.15%.Most HIV /AIDS of MSM,heterosexual transmission and inject -drugs were distributed in Wu Xing District,which accounting for 67.26%,51.42% and 64.71%,respectively.51.15% HIV /AIDS were detected by clinical test.Conclusion The reported cases of HIV /AIDS were still mainly transmitted by heterosexual contact in recent years in Huzhou City,and the constituent ratio of MSMtransmission has increased slightly.
ABSTRACT
Objective To learn the infection status of sexually transmitted diseases (STDs)and acquired immunodeficiency syndrome (AIDS)among female sex workers (FSWs)in Huzhou,and to learn the awareness rate of knowledge of AIDS, and to provide scientific evidence for the development of prevention and control measures.Methods According to the national AIDS surveillance standards,a questionnaire survey was conducted among FSWs and blood samples were collected to detect the antibodies to human immunodeficiency virus (HIV),syphilis and hepatitis C virus.Results A total of 800 FSWs,with an average age (25. 5 ±5. 0 years old)were investigated,and the awareness rate of AIDS related knowledge was 92. 0%.The positive rate of syphilis antibody was 2. 9%and the positive rate of hepatitis C antibody was 0. 2%.HIV antibody was tested negative.The persistent condom use rate among commercial sex workers was 57. 6% in the recent month.The awareness rate of AIDs related knowledge among FSWs with senior middle school education and above was 3. 51 times of those with primary school education and below.Conclusion The prevalence of syphilis and hepatitis C infection among FSWs were high in Huzhou.It is necessary to strengthen the health education among FSWs to improve the awareness of the knowledge,especially for those with low level education.And it is necessary to improve the accessibility of AIDs prevention service to reduce the spread of HIV.
ABSTRACT
Objective To preliminarily evaluate the ability of 15 -loci variable number tandem repeats on the genotyping of clinical isolates of mycobacterium tuberculosis,and explore the suitable loci for genotyping of Mycobacterium tuberculosis in Huzhou City.Methods From 201 1 January to 201 1 April,the clinical isolates of mycobacterium tuberculosis were selected from Huzhou area to test the polymorphism of every loci by using MLVA detection method and analyze hunter-gaston discriminatory index of individual locus as well as combinations of 15 locus.Results There were two locus of Mtub-21 and Mtub-39 which had better degree of polymorphism;seven locus of ETR-A,ETR-C,MIRU-10,MIRU-23,MIRU-27,MIRU-40 and Mtub-30 had moderate degree of polymorphism;six locus of ETR-B,ETR-D,ETR-E,MIRU-16,MIRU-26 and MIRU-39 had poor degree of polymorphism.By calculation,the result showed that HGDI was 0.99 by using 15 locus to genotype,which indicated the ability to distinguish the genotype was good.Conclusion We will continue to look for other rich VNTR polymorphism locus to fit the local region fast genotyping of mycobacterium tuberculosis for higher resolution and cost effectiveness of mycobacterium tuberculosis control and prevention.