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Objective@#To study the relationship between exposure factors in early pregnancy and preterm birth (PB), low birth weight (LBW) and small for gestational age (SGA) of neonates.@*Methods@#A total of 3 172 pregnant women who were enrolled in the project of Chinese Pregnant Women Cohort Study-Peking Union Medical College (CPWCS-PUMC) from July 25, 2017 to July 24, 2018 and delivered before December 31, 2018 were selected as subjects in this study. The relationship between exposure factors in early pregnancy and adverse outcomes of neonatal delivery was analyzed by using binary logistic regression analysis.@*Results@#The incidence rates of PB, LBW and SGA were 4.76%, 3.53% and 5.74%, respectively. In terms of PB, the analysis results showed that the gestational weight gain (GWG) and living in northern China were protective factors, while premature rupture of membranes, gestational hypertension, dental examination or treatment within 1-3 years and family with 3-4 members were risk factors. In the respect of LBW, GWG and daily consumption of milk and dairy products were the protective factors, while premature rupture of membranes, gestational hypertension, sedentary working time more than 6 hours, dental examination or treatment within 1-3 years and passive smoking were risk factors. For SGA, baby girl, passive smoking, peanut oil consumption and unsalted taste were risk factors, while folic acid supplementation was protective factor.@*Conclusion@#The risk factors for PB, LBW and SGA were multifactorial, and relevant specific measures should be taken to reduce the occurrence of adverse neonatal outcomes.
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Objective@#To explore oral health care behavior and related factors among women in their 1st trimester.@*Methods@#Our analysis included 7 014 women in their 1st trimester aged 16 years or above from the baseline survey of the Chinese Pregnant Women Cohort Study (CPWCS). Data on socio-demographic characteristics and oral health care behavior were collected using an electronic questionnaire. Multiple-factors Logistic regression was used to analyze factors associated with oral health care behavior.@*Results@#The results revealed that 5 134 (73.20%), 2 482 (35.39%), and 1 046 (14.91%) pregnant women brushed their teeth twice a day or more, never had an oral examination, and used special oral care products for pregnant women, respectively. The frequency of brushing teeth and oral examination was positively associated with age and annual household income. Compared to unemployed pregnant women with rural registered residences and low education levels, highly educated and employed pregnant women with city registered residences had a higher frequency of brushing teeth and undergoing oral examination. Pregnant women with depressive symptoms had a lower frequency of brushing teeth (OR=0.73, 95% CI: 0.65-0.81), while those with medical insurance underwent more frequent oral examination (OR=1.19, 95% CI: 1.02-1.39). Compared to pregnant women who were unaware of the risk of gingivitis, those who believed gingivitis to be harmful to both themselves and their fetus had a higher frequency of brushing teeth and oral examination and were more likely to use special oral care products.@*Conclusion@#Most pregnant women did not pay attention to the need for oral examinations and special oral care products. Their oral health behavior was associated with socioeconomic status, depressive symptoms, and awareness of the importance of oral health. Therefore, oral health care before and during pregnancy was required to help them improve their self-care behavior.
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Objective To investigate the current status of prevalence,treatment,and management on hypertension among Chinese adults from the National Demonstration Areas for Comprehensive Prevention and Control of Non-communicable Diseases.Methods We selected a total of 4 000 residents aged ≥ 18 years for this questionnaire-based survey by multi-stage clustering sampling in 10 National Demonstration Areas between November and December,2016.Results There were 3 891 effective questionnaires.The self-reported prevalence of hypertension among aged ≥35 years was 31.47％ (1 011/3 213).For the past two weeks,the self-reported treatment of hypertension was 86.75％(877/1 011),with the rates of guidance as 56.87％ (575/1 011) on physical activity,40.95％ (414/1 011) on diet,38.33％ (385/1 011) on weight management,and 22.75％ (228/1 011) on smoking cessation.For the past 12 months,74.68％ (755/1 011) of the residents aged ≥35 years were under the proper management and 62.12％ (628/1 011) of them were under the standardized management programs.The follow-up program lasted for 4 (P2s-P75:4-12) times per year,with 15 (P25-P75:10-20)minutes per each visit.Hypertensive patients would mainly visit the outpatient clinics (53.51％),followed by home visits (22.91％) and telephone calls (13.64％).Rate of satisfaction on management services was 94.83％ (716/755) from the hypertensive patients.Multivariate analysis showed that the rate of self-reported treatment (OR=1.986,95％ CI:1.222-3.228) and self-reported standardized management (OR=2.204,95％CI:1.519-3.199) on hypertension were higher in the Demonstration Areas with higher implementation scores of self-reported non-communicable diseases management.Conclusions Prevention and management on hypertension in the Demonstration Areas had met the requirement set for the Demonstration Areas during the "12th Five-Year Plan".Projects on setting up the National Non-communicable Diseases Demonstration Areas had played an active role in promoting the standardized management program on hypertension.
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Objective To assess the implementation and impact of programs carried out by the National Demonstration Areas for Comprehensive Prevention and Control of Non-communicable Diseases.Methods Both sociological and epidemiological methods were used to collect qualitative and quantitative data in November and December,2016 in order to conduct on process and outcome evaluation of the above mentioned objective.In the meantime,case study was also conducted.Results All the National Demonstration Areas for Comprehensive Prevention and Control of Non-communicable Diseases were found well implemented across the country,with health education and health promotion,surveillance and safeguard measures in particular.A government-led and inter-sector coordination and communication mechanism had been well established,with more than 16 non-health departments actively involved.28.7％ of the residents living in the National Demonstration Areas for Comprehensive Prevention and Control of Non-communicable Diseases were aware of the key messages related to chronic diseases.Among the residents,72.1％ of them consumed vegetables and 53.6％ consumed fruits daily,with another 86.9％ walked at least 10 minutes per day.Over 70％ of the patients with hypertension or diabetes reported that they were taken care of by the Community Health Centers,and above 50％ of them were under standardized management.Residents,living in the National Demonstration Areas under higher ranking of implementation scores,were more likely to be aware of relevant knowledge on chronic disease control and prevention (OR=6.591,95％CI:5.188-8.373),salt reduction (OR=1.352,95％CI:1.151-1.589),oil reduction (OR=1.477,95％CI:1.249-1.746) and recommendation on physical activities (OR =1.975,95％ CI:1.623-2.403).Conclusion The implementation of programs carried out by the National Demonstration Areas for Comprehensive Prevention and Control of Non-communicable Diseases had served a local platform for the control and prevention of non-communicable diseases,and thus become an important'carrier'for chronic disease prevention and control programs in China.
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Objective To investigate the current status of prevalence,treatment,and management on hypertension among Chinese adults from the National Demonstration Areas for Comprehensive Prevention and Control of Non-communicable Diseases.Methods We selected a total of 4 000 residents aged ≥ 18 years for this questionnaire-based survey by multi-stage clustering sampling in 10 National Demonstration Areas between November and December,2016.Results There were 3 891 effective questionnaires.The self-reported prevalence of hypertension among aged ≥35 years was 31.47％ (1 011/3 213).For the past two weeks,the self-reported treatment of hypertension was 86.75％(877/1 011),with the rates of guidance as 56.87％ (575/1 011) on physical activity,40.95％ (414/1 011) on diet,38.33％ (385/1 011) on weight management,and 22.75％ (228/1 011) on smoking cessation.For the past 12 months,74.68％ (755/1 011) of the residents aged ≥35 years were under the proper management and 62.12％ (628/1 011) of them were under the standardized management programs.The follow-up program lasted for 4 (P2s-P75:4-12) times per year,with 15 (P25-P75:10-20)minutes per each visit.Hypertensive patients would mainly visit the outpatient clinics (53.51％),followed by home visits (22.91％) and telephone calls (13.64％).Rate of satisfaction on management services was 94.83％ (716/755) from the hypertensive patients.Multivariate analysis showed that the rate of self-reported treatment (OR=1.986,95％ CI:1.222-3.228) and self-reported standardized management (OR=2.204,95％CI:1.519-3.199) on hypertension were higher in the Demonstration Areas with higher implementation scores of self-reported non-communicable diseases management.Conclusions Prevention and management on hypertension in the Demonstration Areas had met the requirement set for the Demonstration Areas during the "12th Five-Year Plan".Projects on setting up the National Non-communicable Diseases Demonstration Areas had played an active role in promoting the standardized management program on hypertension.
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Objective To assess the implementation and impact of programs carried out by the National Demonstration Areas for Comprehensive Prevention and Control of Non-communicable Diseases.Methods Both sociological and epidemiological methods were used to collect qualitative and quantitative data in November and December,2016 in order to conduct on process and outcome evaluation of the above mentioned objective.In the meantime,case study was also conducted.Results All the National Demonstration Areas for Comprehensive Prevention and Control of Non-communicable Diseases were found well implemented across the country,with health education and health promotion,surveillance and safeguard measures in particular.A government-led and inter-sector coordination and communication mechanism had been well established,with more than 16 non-health departments actively involved.28.7％ of the residents living in the National Demonstration Areas for Comprehensive Prevention and Control of Non-communicable Diseases were aware of the key messages related to chronic diseases.Among the residents,72.1％ of them consumed vegetables and 53.6％ consumed fruits daily,with another 86.9％ walked at least 10 minutes per day.Over 70％ of the patients with hypertension or diabetes reported that they were taken care of by the Community Health Centers,and above 50％ of them were under standardized management.Residents,living in the National Demonstration Areas under higher ranking of implementation scores,were more likely to be aware of relevant knowledge on chronic disease control and prevention (OR=6.591,95％CI:5.188-8.373),salt reduction (OR=1.352,95％CI:1.151-1.589),oil reduction (OR=1.477,95％CI:1.249-1.746) and recommendation on physical activities (OR =1.975,95％ CI:1.623-2.403).Conclusion The implementation of programs carried out by the National Demonstration Areas for Comprehensive Prevention and Control of Non-communicable Diseases had served a local platform for the control and prevention of non-communicable diseases,and thus become an important'carrier'for chronic disease prevention and control programs in China.
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Objective To develop the models for predicting the reported legally notifiable diseases in China.Autoregressive integrated moving average (ARIMA) model was applied to forecast the trend of diseases.Methods Cases used for building the model were from of the records of Notifiable Infectious Diseases in China from May 2009 to July 2016 with R software and the model's predictive ability was tested by the data from August 2016 to January 2017.Results A strong seasonal nature was seen in the reported cases of notifiable communicable diseases,with the lowest point in February and highest peak in June.ARIMA (4,1,0) (1,1,1)12 model was established by the team to forecast the notifiable communicable diseases.Data showed that the biggest and lowest relative errors appeared as 9.78％ and 2.21％,respectively,with the mean of the relative error as 5.39％.Conclusion Based on the results of this study,the ARIMA (4,1,0) (1,1,1)12 model seemed to have had the sound prediction of notifiable communicable diseases in China.
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Objective To develop the models for predicting the reported legally notifiable diseases in China.Autoregressive integrated moving average (ARIMA) model was applied to forecast the trend of diseases.Methods Cases used for building the model were from of the records of Notifiable Infectious Diseases in China from May 2009 to July 2016 with R software and the model's predictive ability was tested by the data from August 2016 to January 2017.Results A strong seasonal nature was seen in the reported cases of notifiable communicable diseases,with the lowest point in February and highest peak in June.ARIMA (4,1,0) (1,1,1)12 model was established by the team to forecast the notifiable communicable diseases.Data showed that the biggest and lowest relative errors appeared as 9.78％ and 2.21％,respectively,with the mean of the relative error as 5.39％.Conclusion Based on the results of this study,the ARIMA (4,1,0) (1,1,1)12 model seemed to have had the sound prediction of notifiable communicable diseases in China.
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The bioactive identity of A Ⅱ made in China and overseas was demonstrated in different levers including receptor, organ and whole body in this report. Therefore, the A Ⅱ made in China can be used in various pharmacological researches in stead of imports.