ABSTRACT
Objective To evaluate the significance of combined determination of glutamic acid decarboxylase antibodies(GADA),islet cell antibodies(ICA) and insulin autoantibodies (IAA) in predictive of type 1 diabetes mellitus Methods GADA, ICA and IAA were determined by enzyme linked immunosorbent assay and C peptide by radioimmunoassay Diagnose efficiency were calculated by matrix decision method Results The positive rate of GADA,ICA and IAA(68 8%,43 0% and 39 8%) were significantly elevated in the patients with type 1 diabetes mellitus compared with type 2 diabetes mellitus or normal subjects ( P
ABSTRACT
0.05).As to the urine whether it is from the normal group or the patient group, there was always significant difference between two methods(P
ABSTRACT
Objective:To investigate the factors affecting the pre-analysis quality in clinical chemistry tests,and to recognize the importance of quality control and management before analysis, also to establish the synthetic management system of pre-analysis quality control.Methods:The database of management system was established by VFP6.0,and the common problems were statistically analysed in clinical chemistry tests from June of 1999 to May of 2002, and the qualified rate of samples was made the quality control index of clinical department.Results:The error occurrence rate of clinical chemistry tests was 1.53‰-2.04‰.The error constitution ratio of pre-analysis, mid-analysis and post-analysis were 64.25%,23.83% and 11.92%,respectively.The first four factors affecting the pre-analysis quality were unstandard sampling,delayed sample delivering,unqualified sample,and unstandard preparation of patients.Conclusion:The pre-analysis quality control of clinical chemistry tests is the essential stage in emphasizing quality control and the prerequisite of ensuring the precise and timely results.It needs the effort and participation of laboratory staffs,clinical medical workers and patients.