Expression in disorder on costimulatory molecules CD28 and CD152 of the T lymphocyte of patients with chronic hepatitis B / 中国基层医药

Objective To explore the expression of costimulatory molecules of CD28 and CD152 for patients with chronic hepatitis B(CHB).Methods Flow cytometric analysis was applied to detect the expression level of CD28/CD152 on CD4+ or CD8+ T lymphocyte subpopulations.Results Compared with control group,the percentage of CD4+CD28+ and CD8+CD28+ increased significantly(P