1.
Chinese Journal of Microsurgery
;
(6): 591-594, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-912277
ABSTRACT
Peripheral nerve injury is common in clinical practice. Today, outcomes of peripheral nerve repair are still not satisfactory. Recently, a large number of studies have shown that exosomes and their bioactive substances can repair peripheral nerve injury by mediating axonal regeneration, activating Schwann cells, regulating inflammation and other pathways to restore nerve function. This review aims to summarise and prospect the role and application of exosomes in peripheral nerve repair from the perspective of Schwann cells, mesenchymal stem cells and macrophages derived exosomes and their bioactive substances.