Progress in association between high mobility group protein box 1 (HMGB1) and immune imbalance in primary Sj?gren′s syndrome / 中华微生物学和免疫学杂志

Primary Sj?gren′s syndrome (pSS) is a relatively common autoimmune systemic disease. The pathogenesis of pSS has not been fully elucidated. With the deepening of research, it is found that high mobility group protein box 1 (HMGB1) is associated with the pathogenesis of pSS, and immunomodulatory abnormalities have become a research hotspot. This article reviewed the association between HMGB1 and immune imbalance in the pathogenesis of pSS.

Progress in antimicrobial substances of endophytes / 生物工程学报

Isolation and characterization of metabolites produced by endophytes are significant ways to search for novel natural active substances, proving that the endophytes are the unique resources of newer and more effective compounds. Many new compounds with antimicrobial activity from different endophytes have been isolated so far. These new compounds provide alternatives to fight against multi-drug resistance of microorganisms. This review outlined the major achievements and latest developments of endophytes, including the diversity of endophytes and antimicrobial activity of endophytes, as well as its development in China.