ABSTRACT
Extrapulmonary tuberculosis accounts for up o one third of all cases of tuberculosis and children show a higher predisposition to the development of extra-pulmonary tuberculosis. To review the clinical features of the extrapulmonary tuberculosis in children. Forty one children with extrapulmonary tuberculosis followed in the Children Hospital of Tunis between January 1995 and December 2007 were reviewed. Extrapulmonary tuberculosis constitutes 57.9%of all cases of tuberculosis. Male to female ratio was 0.7 and the mean age was 75 years. The most commonly involved sites were the peripheral lymphadenitis [14 cases] followed by abdominal [11 cases], central nervous system [7 cases], osteoarticular [5 cases] and multifocal [4 cases]. A positive family history of active tuberculosis was detected in 22.5%of the cases. Diagnosis delay was 4.7 months. Sequelae observed during the follow up were: neurosensory in 5 cases, and vertebral deformation in 1 case. Extrapulmonary tuberculosis represents an important fraction of tuberculosis in our study. The most common form is lymph nodes localization followed by abdominal and central system nervous forms. Neurosensory sequelae were frequent in central system nervous tuberculosis
Subject(s)
Humans , Male , Female , Child , Retrospective Studies , Tuberculosis, Lymph Node , Tuberculosis, Meningeal , Tuberculosis, Osteoarticular , Antitubercular Agents , Tuberculosis/diagnosisABSTRACT
Bronchiectasis remains an important cause of chronic suppurative lung disease in the developing world. This study is to describe the epidemiological characteristics, clinical features, underlying aetiologies and Outcome of bronchiectasis in the paediatric hospital of Tunis. A retrospective study of 41 children with bronchiectasis was conducted between January 1994 and December 2006. Diagnosis was made in patients with clinical suspicion of bronchiectasis associated with abnormalities on chest X ray [n=37] and/or on high resolution computed tomography [HRCT] [n=36]. Mean age at diagnosis was 5 years 9 months; [range: 6 months-14 years]. Persistent cough and bronchorhea were the most common symptoms. Fourteen patients [34%] had dyspnoea on first presentation, 11 of them [26.8%] had chest deformation and/or finger clubbing. Haemoptysis was noted in only two cases. Mean time to diagnosis from symptom onset was 2.7 years [range: 2 months- 4 years]. The underlying aetiologies were identified in 52% of patients. Cystic fibrosis [17%], previous pneumonic illness [9.7%], primary ciliary dyskinesia [9.7%] and immunodeficiency [9.7%] were the most common causes. After a mean follow-up of 6.6 years, the annual lower respiratory infection rate decreased from 7.2 +/- 3 to 3.1 +/- 2.6 [p<0.05], Twenty one point nine per cent of patients had chronic respiratory failure and five patients required surgery. Delays diagnosis of bronchiectasis remains important in our country. Congenital and indeterminate aetiologies are the most common forms. Prognosis is poor with a high prevalence of chronic respiratory failure
Subject(s)
Humans , Male , Female , Bronchiectasis/epidemiology , Bronchiectasis/diagnosis , Bronchiectasis/therapy , Treatment Outcome , Respiratory Insufficiency , Retrospective Studies , ChildABSTRACT
Systemic juvenile idiopathic arthritis is a relatively rare disease in childhood. Sometimes, difficulties are encountered because it is a diagnosis of exclusion. The authors describe the clinical, biologic, therapeutic and evolutive characteristics of this affection. It is a retrospective study during a period of 16 years from 1990 to 2005. Inclusion criteria respond to Durban criteria, after exclusion of other etiologies of febrile eruptions. The authors analyse epidemiologic and clinical characteristics of the disease, biologic exams, treatment and evolution. Nine eases are reported during study period. Patients are between 22 month and II year old. Biologic analysis shows an important inflammatory syndrome with a sedimentary rate superior to 80 mm at first hour in average, a white blood cell count superior to ll.000/mm3. the evolution under treatment is characterized by resistance to steroids in one case and dependence to steroids in 2 eases. The complications include a macrophage activation syndrome in 2 cases and complications secondary to steroids in one ease. Systemic juvenile idiopathic arthritis remains a relatively rare disease in childhood. It's management is improved by the emergency of new treatments bnt its evolution is unpredictable
Subject(s)
Humans , Male , Female , Arthritis, Juvenile/therapy , Disease Management , Retrospective Studies , Prognosis , Child , Immunosuppression TherapyABSTRACT
Background: the pediatric medical emergencie's of Tunisian child's hospital service manages all children fifteen years old. It received 45 000 children in year in average
The aims: establish an epidemiologic profile of consultants and study the encountred morbidity
Methods: we made a transversal describing study of the pediatric emergencie's activity during three successive months in 2004 [February, March, April]. We described the characteristics of the population consulting this service, study the severity and immediate behaviours in emergencies
Results: The number of all consultants is 10560 children during these three months. 54.9% of cases are between one month old and two years old, 54.7% of them are boys
The recruitment mode is direct in 92.9% of cases. The maximum of consultants is in the week-ends with an average of 129 patients per day
In the other days of the week, the average number is 115 +/- 27 patients per day ant the extrems are 75 and 225 patients per day. In the morning, a third of the daily activity is made the morbidity is dominated by the pulmonary pathologies in 39.9% of cases, otorhinolarygologic affections in 31.8% of cases, gastroenterologic pathologies in 6.72% of cases and brain system's pathology in 3.43% of cases. The neonatal affection represents 2.74% of total consultants. At the end of the consultations, 38.7% of patients go back home with medical prescriptions. 45.6% of them receive nebulisations and 21.3% are hospitalized. The bulk is the first dysfunction of the emergencies service. The second dysfunction is the inappropriate use of this service which works like a first structure. Some affections such as febrile seizures, pyelonephritis are excessively hospitalized in 97.5% and 100% respectively
Conclusion: The dysfunction of pediatric medical emergencies's service can be improved by sanitary education of the parents about the role of emergencie's service and the formation of the doctors in the management of patients suffering from usual emergencies
Subject(s)
Adolescent , Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Male , Hospitals, Pediatric/statistics & numerical data , Cross-Sectional Studies , Brain Diseases/epidemiology , Gastrointestinal Diseases/epidemiology , /epidemiology , Otorhinolaryngologic Diseases/epidemiologyABSTRACT
Severe hyperlipidaemia in presenting diabetic ketoacidosis was rarely reported in child.We report the case of a three-year-old girl with presenting diabetic ketoacidosis. Family history was negative for hyperlipidaemia. Serum was creamy pink in gross appearance. The child has a hyperlipidaemia with serum triglycerides 18.5 mmo1/1 and serum cholesterol 13.8 mmol/l. The hyperlipidaemia disappeared with insulin therapy within seven days. We study the clinical, laboratory, pathogenic and evolution features of this uncommon trouble in diabetic children
ABSTRACT
Chronic granulomatosis disease [GCD] is a hereditary abnormality of phagocytic cells, frequently revealed by invasive pulmonary Aspergillosis. The authors report the case of 8 year old girl investigates for hypotrophia, recurrent lung disease and hemoptysia. She was treated for pulmonary tuberculosis because of biological inflammatory syndrome, right alveolar, opacity and positive tuberculin skin test. The course was marked by the development of a thoracic wall mass. Anti- aspergillus serology was positive; culture of the thoracic mass puncture and bronchoalveolar lavage isolated fumigatus Aspergillus. GCD was suggested and confirmed by the NBT test