1.
Chinese Journal of Rehabilitation Theory and Practice
;
(12): 650-653, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-702529
ABSTRACT
Spinal cord injury (SCI) is a disabling disease usually caused by trauma. The treatment and nursing of SCI patients has brought great economic burden to the society. This article introduced the mechanism of riluzole in treating spinal cord in-jury, including blocking Na+channels, reducing glutamate-mediated excitotoxicity, promoting the expression of neuro-trophic factors, and alleviating cellular oxidative stress damage and apoptosis, and the research progress on clinical trials of riluzole.