Preservatives in eyedrops: the advantages, the disadvantages and the countermeasure of use / 中华实验眼科杂志

Preservative is added to multidose eyedrops to ensure that the eyedrops do not become heavily contaminated during patient use,if the active component in the eyedrops do not have a potent antimicrobial effect.There is a large body of evidence from experimental and clinical studies showing that the long-term use of eyedrops with preservative may induce ocular surface damage.It is a system engineering to control the microbial contamination of eyedrops and to relieve ocular surface damage of preservatives.It is the responsibility of drug regulatory departments,the duty of the medicine workers,and the innovativeness studys of the scientific researcher.Then,the best benefit is acquired by the extensive patient with eye disorders.