ABSTRACT
Aims: the goal of the present study was to determine the in vitro antibiotics susceptibility of the L. pneumophila isolated from water of dental units
Methods and Results: Ninety dental units were screened at five teaching dental clinics in Najaf city during February to April 2016. Ninety four water samples were collected from air/water syringe, high-speed hand piece and water bottles of dental units, Totally 9 [9.5%] isolates of Legionella pneumophila were obtained using based charcoal yeast extract [BCYE] culture media and more confirmed by polymerase chain reaction [PCR] assay, The antibiotic susceptibility patterns of 16 antibiotics were studied by disk diffusion test. Present study revealed that all L. pneumophila isolates [100%] recorded fully resistant for ten tested antibiotics. At the same time over 75% isolates were resistant to amoxicillin and tetracycline. Except [55-66%] of isolates exhibited a partial susceptibility to ciprofloxacin, doxycycline and chloramphenicol. Eight [88.8%] of them were extensive resistant [XDR] isolates as well as, Amikacin was highly effective drug
Conclusions: We conclude that, high occurrence of XDR L. pneumophila isolates in contaminated water of dental units in Najaf hospital settings, which has been reported as an etiological agents for hospital-acquired respiratory tract infection
Significance and impact of study: Statistical analysis showed that may considered significant result [P < 0.05] of extensive drug resistance [XDR] isolates