ABSTRACT
Massive pulmonary embolism [PE] is not an uncommon condition, and it usually carries a high risk of mortality. It is one of the fatal conditions that commonly affect young patients. A definitive treatment for patients with massive PE is still lacking, and surgical intervention carries a substantial mortality risk. Thus, percutaneous intervention [clot fragmentation and/or aspiration] remains an option in some patients, specifically in those with a risk of bleeding, contraindicating the use of thrombolysis. There have been no randomized trials to validate percutaneous intervention in massive PE. A sufficient level of evidence is still lacking, and its use depends upon the expert committee's opinion and study of previous case reports. We present a 23-year-old man with first onset massive PE secondary to protein C deficiency, who was treated successfully with the combination of systemic thrombolysis and percutaneous interventions
ABSTRACT
Transient cortical blindness is extremely rare but usually reversible complication of coronary angiography. We report a case of transient cortical blindness in a 63 year old male patient one hour after native coronary and bypass graft angiography through the right femoral access. A non-contrast enhanced CT and MRI brain scans showed multiple asymmetrical lesions in brain parenchyma in the distribution of posterior cerebral circulation predominantly in the cerebellum and left occipital lobe. Direct contrast neurotoxicity to the sensitive occipital cerebral lobes seemed to be the possible cause but the exact mechanism of cerebral injury remains unknown