ABSTRACT
Objective: to determine the frequency of restrictive pulmonary dysfunction in type 1 and type 2 diabetic patients and to measure the severity of pulmonary dysfunction
Material and Methods: this study included 255 patients of type I and type II diabetes who had followed up in the out patient departments of Pulmonology and Medicine in Mayo Hospital, Lahore. Forced vital capacity [FVC] and forced expiratory volume in 1 second [FEV1] were measured using standard spirometry
Results: mean age was 47.26+/-19.076 years. 230 [90.2%] were males and 25 [9.8%] were females. 58 [22.7%] were type 1 diabetics and 197 [77.3%] were type 2 diabetics. 37 [14.5%] had restrictive pathology, 6 [2.4%] had obstructive pathology and 212 [83.1%] had normal lung function tests. 35 [13.7%] had mild restrictive dysfunction and 2 [0.8%] had moderate restrictive lung dysfunction
Conclusion: These data support the notion that the lung is a target organ for diabetic injury. Additional research is required to identify pathophysiologic mechanisms and to determine clinical significance