ABSTRACT
To investigate whether ischemic postconditioning (IPTC) can promote the recovery of left ventricular impaired regional or global longitudinal systolic function. Methods: The trial was divided into a percutaneous coronary intervention (PCI) group, an PCI+IPTC group and a control group. Thirty-two patients with anterior acute anterior wall ST-segment elevation myocardial infarction (STEMI) underwent the first emergency PCI in the PCI group, 28 patients with anterior acute STEMI underwent the combination of PCI and IPTC in the PCI+IPTC group, while 30 patients underwent coronary angiography in the control group. Two-dimensional dynamic echocardiography was collected before operation, 0.5 h, 1 day, 3 days, 1 week, 1 month and 6 months after operation, respectively. The longitudinal strain parameters at different time points were analyzed and compared in the 3 groups. Results: The regional longitudinal strain of infracted segments in the PCI+IPTC group after the operation within 1 week was higher than that in the PCI group (P0.05). There was no significant difference in the long-term regional and global longitudinal strains of left ventricle between the PCI+IPTC group and the PCI group (both P>0.05). Conclusion: The IPTC can improve the short-term longitudinal systolic function of the reperfused myocardium in patients with acute anterior wall STEMI after PCI.
Subject(s)
Humans , Anterior Wall Myocardial Infarction , Ischemic Postconditioning , Myocardium , Percutaneous Coronary Intervention , ST Elevation Myocardial Infarction , Treatment Outcome , Ventricular Function, LeftABSTRACT
Objective To explore the spatio-temporal epidemic trends and related driving effects of meteorological factors on brucellosis in Datong city,Shanxi province,from 2005 to 2015.Methods We collected the surveillance data on brucellosis and related meteorological data in Datong city from 2005 to 2015,to describe the epidemic characteristics of the disease.Quasi-Poisson distribution lag non-liner model (DLNM) was built to explore the driving effect of monthly meteorological data on the disease.Results From 2005 to 2015,Datong city reported a total of 17 311 cases of brucellosis including one death,with the annual average incidence as 47.43 per 100 000 persons.A rising trend was seen during the study period.The monthly incidence of Brucellosis presented an obvious curve with a major peak from March to June,accounted for 48.40％ of the total cases.The high incidence areas in the city gradually expanded from the northeast and southeast to the western areas.Results fiom the DLNM studies suggested that seasonality of brucellosis in Datong was significantly affected by metrological factors such as evaporation,rainfall and temperature.The peak of delayed effect appeared the highest when the monthly cumulative evaporation capacity was 140-260 mm and the monthly cumulative rainfall was 20-60 mm with lag less than 1 month or the monthly temperature was-13 ℃ with lag of 4-5 months.Conclusions The incidence of human brucellosis in Datong city increased significantly from 2005 to 2015.Meteorological factors such as evaporation,rainfall,temperature all showed significant driving effects on the disease.
ABSTRACT
Objective To explore the spatio-temporal epidemic trends and related driving effects of meteorological factors on brucellosis in Datong city,Shanxi province,from 2005 to 2015.Methods We collected the surveillance data on brucellosis and related meteorological data in Datong city from 2005 to 2015,to describe the epidemic characteristics of the disease.Quasi-Poisson distribution lag non-liner model (DLNM) was built to explore the driving effect of monthly meteorological data on the disease.Results From 2005 to 2015,Datong city reported a total of 17 311 cases of brucellosis including one death,with the annual average incidence as 47.43 per 100 000 persons.A rising trend was seen during the study period.The monthly incidence of Brucellosis presented an obvious curve with a major peak from March to June,accounted for 48.40％ of the total cases.The high incidence areas in the city gradually expanded from the northeast and southeast to the western areas.Results fiom the DLNM studies suggested that seasonality of brucellosis in Datong was significantly affected by metrological factors such as evaporation,rainfall and temperature.The peak of delayed effect appeared the highest when the monthly cumulative evaporation capacity was 140-260 mm and the monthly cumulative rainfall was 20-60 mm with lag less than 1 month or the monthly temperature was-13 ℃ with lag of 4-5 months.Conclusions The incidence of human brucellosis in Datong city increased significantly from 2005 to 2015.Meteorological factors such as evaporation,rainfall,temperature all showed significant driving effects on the disease.
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Objective To investigate the clinical significance of velocity vector imaging(VVI)in evaluating the left ventricular(LV)segmental longitudinal systolic function in patients with coronary artery disease(CAD).Methods In 25 patients with myocardial ischemia,28 patients with myocardial infarction,26 patients with coronary lumen stenosis＜50%,according to coronary arteriography and electrocardiogram,the myocardial segments of LV were divided into 4 groups:ischemic segments group,infarcted segments group,non-ischemic segments group and normal segments group.Twenty-eight healthy subjects were selected as control group.Dynamic imaging of all subjects were collected,the systolic peak strain(Smax)and strain rate(SRmax),the time to peak strain(PTs)and the time to peak strain rate(PTsr)were measured respectively.Results Smax and SRmax of the ischemic segments and infracted segments were significantly lower than those of the control group respectively,PTs and PTsr of the ischemic segments and infracted segments were significantly longer than those of the control group respectively.Smax and SRmax of infarcted segments were significantly lower than those of the ischemic segments,there were no differences of PTs and PTsr between ischemic segments and infracted segments.Smax and SRmax cutoff of -14.08%,-0.83 s-1 for detecting ischemic segments and cutoff of -6.65%,-0.38 s-1 for detecting infracted segments,respectively,gave an optimal sensitivity and specificity.Conclusions VVI is a kind of novel noninvasive-tool to quantitatively assess LV regional systolic function in CAD patients.It is competent to differentiate between the ischemic segments and infarcted segments.