ABSTRACT
Diosgenin is the main and the most important extract of crude fenugreek seeds which was thought to be a precursor of steroidal materials. To advice Diosgenin application in future as a cheep ovulatary stimulator material, or as a low cost contraceptive pill. Sixty uncoupled female rats and mice were enrolled in this study, categorized into groups as mentioned in the text. Prolactin, estradiol and progesterone serum levels where, measured for all groups. Histological and statistical analytical methods were applied to identify the increase in the folliculogenis process within the ovaries of the studied animals. An elevation in prolactin, estradiol and progesterone serum levels was established in this study in all the experimental groups when compared to the control. These findings were confirmed histologically as shown in the figures present in the text. In conclusion we can use the extracted diosgcnin from the crude fenugreek seed's in medicine as an ovulatary stimulator material or as a low cost contraceptive pill depending on the dose given and the duration of treatment