ABSTRACT
Chronic non-infectious diseases (hereinafter referred to as "chronic disease") have become a serious public health problem which affect the physical and mental health. Its prevention and control is urgent. Primary osteoporosis is a common chronic disease, which has complex causes, long duration, protracted illness, and poor prognosis, and is often accompanied by fracture and other serious complications. Control strategies of TCM are identify the risk factors of TCM and assess the risk of illness; follow the clinical practice guidelines in Western medicine and TCM and attach great importance to the high-quality evidence of TCM; collect TCM information of study population and established the biobank through long-term follow-up study. The specific method was: according to the TCM theory of "treat pre-disease", the clinical epidemiological investigation and experimental research methods are combined to carry out disease prevention and control work. In the stage of normal bone mass or osteopenia, the clinical efficacy of TCM program in improving bone mineral density were mainly evaluated. In the stage of osteoporosis (fracture has not yet occurred), the main object was to verify efficacy and safety of TCM or integrative programs preventing the fracture. In osteoporotic fracture phase, the focus was to evaluate whether the combination therapy programs could promote healing, prevent recurrence of the fracture and improve the quality of life, thus reducing morbidity and mortality.
ABSTRACT
Objective To analyze the population characteristics, diagnostic characteristics and drug characteristics of patients with ovarian malignant tumor in the real world; To provide references for the clinical rational use of Fufang Kushen Injection.Methods Based on the electronic medical data warehouse of hospital information system of 39 hospitals from nationwide,the use of Fufang Kushen Injection in the treatment and diagnosis of electronic health data in patients with ovarian malignant tumor from August 2003 to December 2014 were extracted. Analysis of frequency and rate were based on the description of the demographic information, diagnosis information, records information such as the characteristics of prescription drugs. Result Data of 22 hospitals, including 1510 cases of patients with ovarian malignant tumor. The average age of patients was (54.93±12.75) years old, and obstetrics and gynecology department and oncology department had the most hospitalized patients, and outpatient admission is the most common hospitalized way. The single dose was (14.53±4.24)mL, and the course of treatment was (6.62±5.49)d.In the treatment of ovarian malignant tumors, combined western medicines were mainly anti-tumor chemotherapy drugs, immunomodulators, hepatoprotective agents, H1 receptor antagonists and electrolyte balance regulator, while combined TCM were clearing heat and antidote medicine, tonifying yang qi medicine, tonifying qi medicine, regulating qi medicine, and hemostatic medicine. The total effective rate was 47.85%. Conclusion Population characteristics of Fufang Kushen Injection in the treatment of ovarian malignant tumors are clear;and the real world clinical dosage, course of treatment with instructions related to define the scope of the basic varieties. Clinical combination has a wide range of drugs.