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By using Zinc nitrate as precursor and hydraZine hydrate as reducing agent, polydiallyl dimethyl ammonium chloride modified reduced graphene oxide/Zinc oxide composite materials ( PDDA-rGO/ZnO) were prepared by simultaneous reduction of graphene oxide ( GO) and Zinc nitrate.The composite materials were characteriZed by Fourier transform infrared ( FTIR ) spectroscopy, X-ray diffractometer ( XRD ) and transmission electron microscopy ( TEM) , and their electrochemical catalytic activity for uric acid was studied by cyclic voltammetry ( CV ) and linear sweep voltammetry ( LSV ) measurements.The result showed that PDDA-rGO/ZnO modified glassy carbon electrode prepared here was sensitive, reproducible and stable, and had significant electrocatalytic activity for UA.When using linear sweep voltammetry for detection of UA, the responses of modified electrode were linear with UA concentration in the ranges of 0.02-0.1 mmol/L and 0.1-1.0 mmol/L respectively, with detection limit of 15.9 nmol/L (S/N=3).
ABSTRACT
Objective:To investigate the effect of general or regional anesthesia on postoperative cardiopulmonary complications and inpatient mortality after hip fracture surgery in elderly patients.Methods:A retrospective analysis was conducted according to the medical records of 572 elderly patients with hip fractures admitted to our hospital from January 1,2005 to December 31,2014.The age,gender,preoperative comorbidities,length of preoperative bedridden time,mechanism of injury,surgical types,anesthetic methods,major postoperative complications and inpatient mortality were recorded.Multivariate Logistic regression analysis was applied to analyze the impact of different anesthetic methods on inpatient mortality in these patients.Results:Of the 572 patients,392 (68.5％) received regional anesthesia.Inpatient death occurred in 8 (8/572,mortality:1.4％),including 5 cases of RA group (5/392,mortality:1.3％) and 3 cases of GA group (3/180,mortality:1.7％).There was no statistically significant difference between the two groups in inpatient mortality (P ＞ 0.05).Multiple Logistic regression analysis showed that gender (odds ratio:0.18,95％ CI:0.03-1.05,P =0.057),age (odds ratio:1.22,95％ CI:1.07-1.38,P =0.002),preoperative pulmonary comorbidities (odds ratio:12.09,95％ CI:2.28-64.12,P =0.003) and surgical types (odds ratio:9.36,95％ CI:1.34-64.26,P =0.024) were risk factors for inpatient mortality.Postoperative cardiovascular complications occurred in 36 patients (36/572,morbidity:6.3％),with 19 patients in RA group (19/392,morbidity:4.8％),and 17 patients in GA group (17/180,morbidity:9.4％).Multiple Logistic regression analysis showed that age (odds ratio:1.13,95％ CI:1.07-1.19,P ＜ 0.001),hypertension (odds ratio:2.72,95％ CI:1.24-5.96,P =0.012) and preoperative cerebral comorbidities (odds ratio:2.11,95％ CI:0.99-4.52,P =0.054) were risk factors for postoperative cardiovascular complications.Postoperative pulmonary complications occurred in 56 patients (56/572,morbidity:9.8％),with 19 patients in RA group (19/392,morbidity:4.8％),and 37 patients in GA group (37/180,morbidity:20.6％).Multiple Logistic regression analysis showed that age (odds ratio:1.13,95％ CI:1.07-1.19,P ＜0.001),preoperative pulmonary comorbidities (odds ratio:2.89,95％ CI:1.28-7.05,P=0.020),length of preoperative bedridden time (odds ratio:1.11,95％ CI:1.04-1.18,P =0.003) and anesthetic methods (odds ratio:5.86,95％ CI:2.98-11.53,P ＜ 0.001) were risk factors for postoperative pulmonary complications.Conclusion:General anesthesia may not affect the inpatient mortality after hip fracture surgery in elderly patients.Regional anesthesia is associated with a lower risk of pulmonary complications after surgical procedure compared with general anesthesia.
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Objective To investigate the cognition and attitude towards free pneumonia vaccination among elderly people aged over 60 years old in Minhang District of Shanghai.Methods Target population was based on registered citizen over 60 years old in Minhang District.According to their willingness of pneumonia vaccineinjection,participants were divided into two groups,willing group and refused group.We randomly selected 910 people for each group.And before vaccination,a self-made "pneumonia vaccination behavior cognition and attitude questionnaire" was completed by each participant.Whether there were significant differences in the cognitive and attitude towards pneumonia vaccination between the two groups was analyzed by t test.x2 test and Logistic regression model was used to analyze main risk factors affecting the elderly attitude and behavior towards pneumonia vaccination.Results Statistical significant relations were found among following five cognition dimensions,which were benefits of vaccination (t =21.691,P＜0.01),values of vaccination (t =6.105,P＜0.01),the severity of affecting pneumonia (t =9.882,P＜0.01),vulnerable of getting pneumonia (t =5.670,P＜0.01) and obstacle towards vaccination (t =-7.114,P＜0.01).x2 test and Logistic regression analysis results suggested that among these five dimensions,cognition of vaccination benefits (B =0.610,P＜0.01) played the most important role in the attitude of elderly people between the two groups.The severity of affecting pneumonia (B =-0.452,P＜0.01) and obstacle towards vaccination (B =0.311,P＜0.01) played less important role regards elderly making decision of taking pneumonia vaccination.There was no statistically significant relations in sensitivity of getting pneumonia.In addition to the five dimensions discussed above,people who are engaged in commercial and service industry before retirement,with an annual income of between ten thousand to one hundred thousand and having chronic diseases are more likely to have a higher degree of acceptance of taking pneumonia vaccine than those without these properties.Conclusions There were significantly differences in cognitive behavior between willing to injection group and refused group among elderly.The results suggest that the benefits of pneumonia vaccination in older people with chronic diseases may have a positive effect on further increasing the rate of free pneumonia vaccination in the elderly population in Minhang District of Shanghai.
ABSTRACT
Objective To investigate the cognition and attitude towards free pneumonia vaccination among elderly people aged over 60 years old in Minhang District of Shanghai.Methods Target population was based on registered citizen over 60 years old in Minhang District.According to their willingness of pneumonia vaccineinjection,participants were divided into two groups,willing group and refused group.We randomly selected 910 people for each group.And before vaccination,a self-made "pneumonia vaccination behavior cognition and attitude questionnaire" was completed by each participant.Whether there were significant differences in the cognitive and attitude towards pneumonia vaccination between the two groups was analyzed by t test.x2 test and Logistic regression model was used to analyze main risk factors affecting the elderly attitude and behavior towards pneumonia vaccination.Results Statistical significant relations were found among following five cognition dimensions,which were benefits of vaccination (t =21.691,P＜0.01),values of vaccination (t =6.105,P＜0.01),the severity of affecting pneumonia (t =9.882,P＜0.01),vulnerable of getting pneumonia (t =5.670,P＜0.01) and obstacle towards vaccination (t =-7.114,P＜0.01).x2 test and Logistic regression analysis results suggested that among these five dimensions,cognition of vaccination benefits (B =0.610,P＜0.01) played the most important role in the attitude of elderly people between the two groups.The severity of affecting pneumonia (B =-0.452,P＜0.01) and obstacle towards vaccination (B =0.311,P＜0.01) played less important role regards elderly making decision of taking pneumonia vaccination.There was no statistically significant relations in sensitivity of getting pneumonia.In addition to the five dimensions discussed above,people who are engaged in commercial and service industry before retirement,with an annual income of between ten thousand to one hundred thousand and having chronic diseases are more likely to have a higher degree of acceptance of taking pneumonia vaccine than those without these properties.Conclusions There were significantly differences in cognitive behavior between willing to injection group and refused group among elderly.The results suggest that the benefits of pneumonia vaccination in older people with chronic diseases may have a positive effect on further increasing the rate of free pneumonia vaccination in the elderly population in Minhang District of Shanghai.