ABSTRACT
Objective To investigate the expression of transforming growth factor-?(TGF-?) in the villus and deciduas of different outcomes after administration with mifepristone and misoprostol in the termination of early pregnancy. Methods From May 2004 to March 2005,50 women who were comfirmed early pregnancy and requested termination of pregnancy in the outpatient department were recruited.Patients with medical abortion were divided into two groups according to the final outcomes: group of complete abortion(n=15) and group of incomplete abortion((n=)15).Another 20 patients with surgical abortion were served as control.The villus and deciduas were collected at the third day of medical abortion,whereas the same was done at the day of surgical abortion.The expression of TGF-? in villus and deciduas of the three groups were measured by immunohistochemical method. Results The age,gestational age,diameter of gestational sac and levels of serum E_(2),P and ?-HCG before abortion were similar in these groups.Compared with the other two groups,the expressions of TGF-? in the villus and deciduas in the group of complete abortion were significantly decreased(P
ABSTRACT
ObjectiveTo evaluate Trichosanthin(TCS) in treating ectopic pregnancy by com-paring to clinical efficacy and side effects between the intramuscular and intracervical adiministrationgroup. MethodsTCS was given to the patients by either the intracervical or the intramuscular route.Compare the clinical results. ResultsThere was a 90% cure rate in the intramuscular injection groupand a 94% cure rate in the intracervical injection group. Side effects were slighter in the intracervical in-jection group than intramuscular injection, especially in fever and its sustained time (P<0.05)。ConclusionsThe clinical efficacy was consistent in two groups but the side effects of the intra - cervicalgroup were slighter.