ABSTRACT
Henoch-Scholein purpura(HSP)is a common systemic vasculitis of the small vessel in children,with a variety of clinical manifestations.The main diagnostic criteria include palpable skin purpura.Patients who have gastrointestinal tract as the main symptoms suffer clinically abdominal pain and gastrointestinal bleeding,they are easily misdiagnosed before skin purpura,the rate of misdiagnosis can be as high as 87.5%,and the main treatment is early application-oriented glucocorticoids.This review include etiopathogenisis,pathogenesis,pathology,clinical manifestations,auxiliary examination and treatment about gastrointestinal manifestations in HSP.
ABSTRACT
<p><b>OBJECTIVE</b>To study the polysaccharide of Condonopsis pilosula.</p><p><b>METHOD</b>The polysaccharide, CPP-1, was purified by DE-52 cellulose and Sephadex G-200 gel column chromatography. Purity and molecular weight of the polysaccharide were determined by gel permeation chromatography. Methylation analysis, periodate oxidation and degradation, IR, 1H-NMR and 13C-NMR methods were adopted to elucidate the chemical structure.</p><p><b>RESULT</b>The molecular weight of CPP-1 was estimated to be 7.5 x 10(4), and the structure of CPP-1 was a beta-(2 --> 1) linked beta-D-fructosan.</p><p><b>CONCLUSION</b>CPP-1 was a neutral homosaccharide.</p>
Subject(s)
Codonopsis , Chemistry , Drugs, Chinese Herbal , Chemistry , Fructans , ChemistryABSTRACT
<p><b>AIM</b>To study the chemical constituents of the pine needles from Pinus massoniana Lamb..</p><p><b>METHODS</b>Various chromatographic techniques were used for the separation and purification. The physicochemical properties and spectral data were used to elucidate the structures.</p><p><b>RESULTS</b>Three compounds were isolated from the n-BuOH fraction of water-extracts. The structures were identified as (7S,8R)-4,9'-dihydroxyl-3, 3'-dimethyoxyl-7, 8-dihydrobenzofunan-1'-propanolneolignan-9-O-alpha- L-rhamnopyranoside (massonianoside D, 7), 4,4',9,9'-tetrahydroxyl-3,3'-dimethyoxyl-tetrahydrocyclolignan ((+)-isolariciresinol, 8) and 4,4',9'-trihydroxyl-3,3'-dimethyoxyl-tetrahydrocyclolignan-9-O-beta-D- xylopyranoside (isolariciresinol-9-O-xyloside, 9) on the basis of spectral data (ORD, UV, IR, MS, 1HNMR, 13CNMR, 1H-1HCOSY, HMQC and HMBC etc.).</p><p><b>CONCLUSION</b>Compound 7 is a new compound, while compounds 8 and 9 were isolated from this plant for the first time.</p>