ABSTRACT
Objective Discuss the efficacy of Yangxueqingnao granule combined with Flunarizine Hydrochloride capsules in treatment of acute cerebral infarction with headache.Methods 110 patients with acute cerebral infarction with headache were selected,they were divided into two groups randomly.The control group (55 cases) was given Flunarizine Hydrochloride Capsules.The observation group (55 cases) was given Yangxueqingnao granule combined with Flunarizine Hydrochloride capsules.The efficacy of Yangxueqingnao granule combined with Flunarizine Hydrochloride capsules in treatment of acute cerebral infarction with headache was evaluated by the efficacy,headache symptom score,ADL scores and adverse reactions during treatment.Results 25 cases were cured in the observation group,markedly effective in 19 cases,effective in 6 cases,the effective rate was 90.9％;18 cases were cured in the control group,markedly effective in 12 cases,effective in 13 cases,the effective rate was 78.2％.The effective rate was higher in the observation group (P ＜ 0.05).Before treatment,there were no statistical significance on headache scores in two groups.2 and 4 weeks after treatment,the headache scores were decreased and the scores were lower in the observation group (P ＜ 0.05).Before treatment,there were no statistical significance on ADL scores between two groups.2 and 4 weeks after treatment,the ADL scores were increased and the scores were higher in the observation group (P ＜ 0.05).During treatment,there were no statistical significance on adverse reaction between two groups.Conclusion Yangxueqingnao granule combined with Flunarizine Hydrochloride capsules have a good therapeutic effect on acute cerebral infarction with headache symptoms.The patients can significantly reduce headache and headache attack frequency.The therapy can improve the ability of daily life of patients with good safety.