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1.
Article in English | WPRIM | ID: wpr-903041

ABSTRACT

Objectives@#To 1) report prevalence of ‘osteosarcopenia’ (OS) and osteosarcopenic obesity (OSO) entities using evidence-based diagnostic techniques and definitions, 2) examine if OSO offers additional predictive value of functional decline over its components, and 3) identify associated factors in a multi-racial Southeast Asian population. @*Methods@#We performed a cross-sectional study of a representative sample of 542 community-dwelling adults (21–90 years old), and assessed anthropometry, cognition, functional performance, and self-report sociodemographic, health and lifestyle questionnaires. Low muscle mass, and the Asian Working Group for Sarcopenia (AWGS) 2019 criteria, were used to assess sarcopenia. Obesity was defined using percentage body fat and fat mass index. Osteopenia/osteoporosis was determined using lumbar spinal bone mineral density. Associated factors were examined using logistic regression, and OSO’s value investigated using linear regressions with functional performance. @*Results@#OS and OSO prevalence were 1.8% and 0% (21–59 years), 12.9% and 2.8% (≥ 60 years), 17.3% and 4.1% (≥ 65 years), and 25.5% and 7.0% (≥75 years), respectively. OSO entity as defined was not a significant predictor (P > 0.05) and did not improve explanations for functional decline over sarcopenia or sarcopenic obesity. Age, sex, race and body mass index (BMI) were associated with OS, while age, sex, race and alcoholism were associated with OSO. @*Conclusions@#Our results do not support OSO as a distinct entity in relation to functional decline. Aside from biological age, sex, and race, amenable lifestyle factors such as BMI and alcohol intake are important variables that can influence the co-existence of osteopenia/osteoporosis, sarcopenia and obesity.

2.
Article in English | WPRIM | ID: wpr-895337

ABSTRACT

Objectives@#To 1) report prevalence of ‘osteosarcopenia’ (OS) and osteosarcopenic obesity (OSO) entities using evidence-based diagnostic techniques and definitions, 2) examine if OSO offers additional predictive value of functional decline over its components, and 3) identify associated factors in a multi-racial Southeast Asian population. @*Methods@#We performed a cross-sectional study of a representative sample of 542 community-dwelling adults (21–90 years old), and assessed anthropometry, cognition, functional performance, and self-report sociodemographic, health and lifestyle questionnaires. Low muscle mass, and the Asian Working Group for Sarcopenia (AWGS) 2019 criteria, were used to assess sarcopenia. Obesity was defined using percentage body fat and fat mass index. Osteopenia/osteoporosis was determined using lumbar spinal bone mineral density. Associated factors were examined using logistic regression, and OSO’s value investigated using linear regressions with functional performance. @*Results@#OS and OSO prevalence were 1.8% and 0% (21–59 years), 12.9% and 2.8% (≥ 60 years), 17.3% and 4.1% (≥ 65 years), and 25.5% and 7.0% (≥75 years), respectively. OSO entity as defined was not a significant predictor (P > 0.05) and did not improve explanations for functional decline over sarcopenia or sarcopenic obesity. Age, sex, race and body mass index (BMI) were associated with OS, while age, sex, race and alcoholism were associated with OSO. @*Conclusions@#Our results do not support OSO as a distinct entity in relation to functional decline. Aside from biological age, sex, and race, amenable lifestyle factors such as BMI and alcohol intake are important variables that can influence the co-existence of osteopenia/osteoporosis, sarcopenia and obesity.

3.
Article in English | WPRIM | ID: wpr-879294

ABSTRACT

Objectives Blood stream infections (BSIs) are the main cause of morbidity and mortality in children worldwide. The present study was carried out to determine the prevalence of BSI with a focus on the identification of the causative agent of BSI, and to further evaluate the antibiotic susceptibility profile of the causing bacterial pathogens.Methods A cross-section study was carried out at the tertiary care hospital in Peshawar, Pakistan from January to December, 2018. Blood samples were collected in BACTEC

4.
Article in English | WPRIM | ID: wpr-780716

ABSTRACT

@#Introduction: Management of disturbed wounds, large skin defects and the areas where skin tension precludes wound closure is of high clinical importance. Healing in wounds occurs through epithelization and contraction processes (second-intentions healing) that may result in certain undesirable complications including keloid and formation of a fragile epithelial layer. Materials and methods: 27 white New Zealand rabbit included in this study divided into 3 groups; one group of 9 rabbits received Flaxseed gel topically for three time intervals (1, 7, and 14 days); a second group received Fucidin cream as positive control, while a third group has not received any treatment as negative control, Skin elasticity measurements were performed using the DermaLab system. Results: Throughout the study, skin elasticity was significantly greater in Flaxseed group than in others. Flaxseed decrease elasticity value from (3.46 ± 2.05). Hence, Young's modulus of skin elasticity in flaxseed group was (2.46 ± 1.02) after 14 days (p = 0.003), while no significant differences were evident in both Fucidin group (1.16 ± 0.77) and non-treated group (1.86 ± 1.40) (p = 0.019), accordingly flaxseed extract more reproducible than other groups demonstrating comparable efficacy in skin elasticity and distensibility. Conclusions: This study showed the therapeutic effect of flaxseed on biologic tissue. Elasticity evaluation demonstrated increased density and firmness in the network of collagen fibers in the dermis and subcutis during wound healing process promise in generating therapeutic gel to be used in wound healing process.

5.
Egyptian Journal of Hospital Medicine [The]. 2018; 70 (9): 1552-1561
in English | IMEMR | ID: emr-192691

ABSTRACT

Background: the knee joint is one of the most commonly injured joints in the body. Because of its complex structure, this joint is subjected to numerous pathologies and due to the recent increase in various sport activities; there has been a parallel increase in sport-induced internal derangements of the knee


Objective: the main objective of our work was to review several of the most common causes of AKP, with emphasis on their MRI findings with the goal of allowing more accurate diagnosis and grading of some of the most common pathologies, for understanding, better treatment and improvement of this common complaint


Patients and Methods: this study included 20 patients [13 females and 7 males]. Their ages ranged between 10 - 70 years [average age 40.8 +/- 5.83 years]. All were presented by anterior knee pain and referred to Radiology Department of Ain Shams University Hospital or private centers for MRI examination after orthopedic consultation


Results: this study included 20 patients, with their ages ranged between 10-70 years, all of them were suffering from anterior knee pain


Conclusion: MRI is generally safe, accurate, and specific modality which has been proven to be the modality of choice in the diagnosis of different knee pathologies that cause anterior knee pain in different age groups

6.
Pakistan Journal of Pharmaceutical Sciences. 2018; 31 (2 Supp.): 727-731
in English | IMEMR | ID: emr-195043

ABSTRACT

Glutathione is an essential antioxidant of living organism that provides a primary protection against metals toxicity. A significant amount of glutathione is present in blood erythrocytes, plasma and liver hepatocytes to protect them from oxidative damage from both external and internal oxidants. Metalo-element palladium has numerous pharmacological, clinical and toxicological compensations, like palladium is used as anti-viral, anti-bacterial, neuroprotective and anti-tumor agent. However studies have also indicated some mild to serious toxic effects of palladium metallo-elements. In the presence study the interaction of palladium inorganic salt and organic complex with glutathione [GSH] content of liver homogenate was examined spectro-photometrically. 20% [w/v] liver homogenate was prepared of the collected liver of rabbit in 5% TCA [tri-chloro-acetic acid] solution and 1mm EDTA, using a potter-eveljhem homogenizer with motor driven Teflon pestle. The GSH content quantification was carried out by Elman's method. Our finding showed that there was a depletion of GSH content by both palladium inorganic salts and organic complexes, concentrations wise as well as with time elapse as level of GSH content decrease from [43.6% to 72.62%] with Palladium Nitrate and from [24.09 to 59.5%] with Bis-benzonitrile Palladium II Chloride as compared to control, and further dropped with time incubation from 0-90 minutes from [49.7 to 87.1%], with Palladium Nitrate and from [29.3% to 67.6%] respectively. The result showed that the effect of both inorganic salt of palladium was more enhanced as compare to its organic complex. It was suggested from our finding that the depletion in the glutathione content of liver homogenate may be due to oxidation of glutathione or due to glutathione metal abduct formation by both inorganic salt and organic complex of palladium. This study in situ is a model of in vivo

7.
PAFMJ-Pakistan Armed Forces Medical Journal. 2018; 68 (3): 510-514
in English | IMEMR | ID: emr-198847

ABSTRACT

Objective: To compare the effectiveness of intraperitoneal and local infiltration of bupivacaine on pain relief in postoperative period after laparoscopic cholecystectomy. Study Design: Randomized controlled trial. Place and Duration of Study: Combined Military Hospital Multan, from Jan to Dec 2014


Material and Methods: In this study, 72 adult patients of either gender with age between 20 to 60 years having symptomatic gallstones scheduled for elective laparoscopic cholecystectomy were divided into two groups. Patients in group A received intraperitoneal and local infiltration of bupivacaine at the end of surgery. Group B was administered placebo. Postoperatively, intensity of pain was recorded by using 10 points' Visual Analogue Score at 3, 9, 12, 24 hours. A p-value

Results: In group A, there were 27 male and 9 female patients while in group B, there were 22 male and 14 female patients. Mean age was 37.75 +/- 12.49 years and 41.92 +/- 12.73 years in groups A and B respectively. The mean postoperative pain score was 8.18 +/- 1, 6.36 +/- 0.98, 4.98 +/- 1.11 and 3.89 +/- 1.11 in group A and 8.72 +/- 1.05, 6.91 +/- 0.96, 5.92 +/- 0.96 and 4.47 +/- 1.05 in group B at 3, 9, 12 and 24 hours post operatively. The difference in mean pain scores was significant; 0.0286, 0.0188, 0.0001 and 0.0258 at 3, 9, 12 and 24 hours respectively


Conclusion: Intraperitoneal and local infiltration of 0.25% bupivacaine significantly reduces the intensity of postoperative pain and analgesic requirement in the early postsurgical hours following laparoscopic cholecystectomy

8.
Oman Medical Journal. 2018; 33 (5): 409-415
in English | IMEMR | ID: emr-201943

ABSTRACT

Objectives: We sought to estimate the prevalence of hypertensive disorders of pregnancy [HDP] in Saudi Arabia as well as the risk factors of HDP, and maternal and fetal outcomes


Methods: We retrospectively evaluated the medical records of 9493 women who delivered at King Abdulaziz University Hospital, a tertiary care center, between January 2015 and June 2017. All cases of HDP were included


Results: We identified 224 pregnant women with HDP in our patient cohort, giving a prevalence of 2.4%. Their mean age was 31.3 +/- 6.7 years, with an average gravidity of 4.0 and average parity of 3.0. The most prevalent subtype of HDP was preeclampsia [54.9%] while 29.5% of the women had gestational hypertension, and 8.0% had eclampsia. The prevalence of subtypes of HDP differed significantly with gravidity, and mean age differed significantly with HDP subtype. Personal and family histories of preeclampsia and the presence of diabetes were more prevalent in women with preeclampsia and gestational hypertension; however, only the difference in diabetes prevalence was significant. The overall prevalence of maternal complications was 9.4% and the prevalence of maternal mortality was 1.3%. Multigravid women and women with chronic hypertension were at increased risk of prematurity compared to other pregnant women, but not significantly


Conclusions: The prevalence of HDP was relatively low in our cohort. However, to prevent harmful impacts on both the mother and fetus, screening for this disorder is recommended early in pregnancy

9.
Pakistan Journal of Pharmaceutical Sciences. 2017; 30 (6 Supp.): 2405-2410
in English | IMEMR | ID: emr-190227

ABSTRACT

Thiol groups are extensively present across biological systems being found in range of small molecules [e.g. Glutathione, Homo-cysteine] and proteins [e.g. albumin, haemo-globin]. Albumin is considered to be a major thiol containing protein present in circulating Plasma. Albumin contains a single thiolate group located at cysteine-34[cys-34] at its active site. Albumin also binds a wide variety of metals and metals complexes at various sites around the protein. Usually heavy metals are preferentially attached with the thiol group of albumin. The binding of heavy metals at cys-34 provides a mechanism by which the residence time of potentially toxic species in the body can be increased. In this research we have assessed the oxidative modification of and metal binding capacity of cys-34 with heavy metals Palladium and Vanadium to investigate the ease with which it is possible to effect disulfide-thiol exchange at this sites/or remove a metal bound at this position. Both the metals were treated with albumin and then the albumin metals [Pd and V] complexes were treated with small thoil molecules like Glutathione, Cysteine and D-Penicillamine. Our finding showed that the albumin thiol group retained the metals with itself by forming some strong bonding with the Thiols group, it is concluded from this finding that if by chance both the metals enter the living system; strongly disturb the chemistry and physiological function of this bio-molecule

10.
Pakistan Journal of Pharmaceutical Sciences. 2017; 30 (1): 199-203
in English | IMEMR | ID: emr-185759

ABSTRACT

The aim of this experimental work was to explore the potential pharmacological activities of Gaultheria trichophylla Royle in hyperactive respiratory and vascular conditions. Gaultheria trichophylla was extracted with solvents, phytochemical detection tests were performed, and rabbit trachea and aorta strips were used to evaluate its effects on airways and vascular smooth muscles. Qualitative phytochemical tests showed the presence of flavonoids, alkaloids, anthraquinones, saponins, terpenoids, and condensed tannins. The methanol extract caused inhibition [EC[50] values of 3.12 mg/mL] of carbachol [1 micro M] and partial relaxation of K[+][80 mM] caused contractions in tracheal strips. The chloroform extract was comparatively more potent against carbachol than K[+] induced contraction with EC[50] values of 0.64 and 2.26 mg/mL, respectively. However, the n-hexane extract showed more potency against K[+] than cabachol induced contractions, as in case with verapamil, with EC[5]0 values of 0.61 and 6.58 mg/mL, respectively. In isolated prepared trachea, the extracts displaced the carbachol concentration response curves and maximum response was suppressed. In rabbit aorta preparations, methanol and n-hexane extracts partially relaxed phenylephrine [1 micro M] and K[+] induced vasoconstrictions. However, the chloroform extract inhibited phenylephrine induced contractions and exhibited a vasoconstrictor effect at lower concentrations and a relaxant effect at higher concentrations against K[+] precontractions. The data indicates that, in addition to others, the extracts of G .trichophylla possess verapamil like Ca[++] channel blocking components which explain the possible role of this plant in respiratory and vascular conditions


Subject(s)
Adult , Animals, Laboratory , Female , Male , Phytochemicals/pharmacology , Phytotherapy , Plants, Medicinal , Muscle, Smooth, Vascular/drug effects , Aorta/drug effects , Calcium Channel Blockers
11.
Medical Forum Monthly. 2016; 27 (9): 62-65
in English | IMEMR | ID: emr-184051

ABSTRACT

Objective: The objective of this study was to evaluate the construction faults associated with complete dentures made by clinical students


Study Design: Descriptive / cross-sectional study


Place and Duration of Study: This study was conducted at Prosthodontics; Department Institute of Dentistry; Liaquat University of Medical and Health Sciences Jamshoro from May 2015 to October 2015


Materials and Methods: Total 197 complete denture wearer's patients were recruited in this study. Faults associated with vertical dimension, centric relation, denture base thickness, finishing and polishing were examined and noted in proforma. Data was analyzed by SPSS version 17.0


Results: Out of 197 patients male and female patients were 56.3% and 43.7% respectively. Vertical dimension was found to be high in 82% patients and centric relation was noted 81% as right and 19% as wrong. According to thickness of denture base plate, 80% were thick and 5% were thin denture base. According to finishing and polishing of dentures, 55% dentures were seen with satisfactory results


Conclusion: It is concluded that the most common faults in construction of complete dentures were high vertical dimension, thick denture base plates and finishing and polishing

12.
Article in English | IMSEAR | ID: sea-166455

ABSTRACT

Background: Objective of current study was to estimate the prevalence of intestinal metaplasia in dyspeptic patients in Duhok (Kurdistan region) and its association with H. pylori and dysplasia according to gender and age. Methods: This was a prospective observational study. Study was conducted from Jan 2012 to Jul 2014 at Azadi Teaching Hospital Duhok City. A total number of 205 antral gastric biopsies were collected in Azadi GIT-Centre and examined histologically to detect intestinal metaplasia. These biopsies were stained by Giemsa to detect H. pylori organisms. Results: H. pylori was found in 94 (46%) patients while intestinal metaplasia in general was found in 30 (15%) patients; (9.8% in association with H. pylori) and (4.7% without H. pylori). Among intestinal metaplasia 6 cases show dysplasia (6/205 = 3%). Conclusions: This study has documented mainly that the prevalence of intestinal metaplasia is significant among patients (In Duhok) with chronic gastritis and mainly in those patients who are positive for H. pylori with an active chronic gastritis. Intestinal metaplasia mostly affects patients above the age of 40 years with no significant gender difference.

13.
PAFMJ-Pakistan Armed Forces Medical Journal. 2015; 65 (5): 630-634
in English | IMEMR | ID: emr-176985

ABSTRACT

To compare the efficacy of Phenol and Sodium Hydroxide Matricectomies in terms of frequency of pain and wound healing in the management of Ingrown Toenails. Randomized Clinical Trial Out Patient Department of Surgery Combined Military Hospital Kharian from Aug 2010 to Feb 2011. A total of 140 cases with Ingrown Toenails were selected and randomly divided into two groups of 70 each. Cases of Group A and B were subjected to Phenol Matricectomy [PMC] and Sodium Hydroxide Matricectomy [SHMC] respectively. Postoperative pain was comparatively and Southampton Wound Grade for wound healing were analyzed at 2[nd] and 10[th] postop day. Mean age of Group A was 28.86 +/- 6.423 whereas that of Group B was 28.80 +/- 5.997. Group A had 58 [83%] males and 12 [17%] females. Group B had 48 [69%] males and 22 [31%] females. Postoperative pain was comparatively less in group A with statistical difference between two groups on 2[nd] day [p = 0.014], whereas it was less intense in group B with no statistical significant difference on 10[th] day [p=0.662]. Wound healing was better in group B with statistical difference between two groups on 2[nd] [p = 0.022] and 10[th] day [p = 0.024]. Group B [91.4%] had more statistically significant efficacy than Group A [71.4%] [p = 0.004]. SHMC is superior to PMC in reducing pain and improving wound healing for managing Ingrown Toenails

14.
Medical Forum Monthly. 2015; 26 (4): 2-4
in English | IMEMR | ID: emr-166518

ABSTRACT

This study was to determine the orthodontic treatment need in local population visiting the Liaquat University of Medical and Health Sciences Hospital by using index of orthodontic treatment need. Descriptive cross sectional study. This study was conducted on patients visiting to Dental outpatient department [OPD] of Liaquat University of Medical and Health Sciences Hospital, Jamshoro from September 2012 to October 2013. Informed written consent was taken from 150 patients' satisfying the inclusion criteria,history and clinical examination was done on patients by using index of orthodontic treatment need. SPSS version 19 was used to analyze the data and frequency was determined for categorical variables. Mean and standard deviation was computed for numerical variables. According to Dental Health Component [DHC] treatment need 36.7%, 34.7%, 24.7% and 4.0% found to have orthodontic treatment need from no little treatment to very great treatment respectively and according to Aesthetic Component [AC] treatment need 49.3%, 44.0% and 6.7% found to have orthodontic treatment need from no little treatment to great treatment need. It was concluded that the patients of this locality found to have increased need for orthodontic treatment


Subject(s)
Adult , Female , Humans , Male , Dental Service, Hospital , Cross-Sectional Studies , Population
15.
Pakistan Journal of Pharmaceutical Sciences. 2015; 28 (4): 1275-1280
in English | IMEMR | ID: emr-165767

ABSTRACT

Tuberculosis [TB] has a long history and being present even before the start of recording history. It has left detrimental effects on all aspect of the life and geared the developments in the science of health. TB is caused by Mycobacterium tuberculosis complex [MTBC] including five species M. tuberculosis, M. bovis, M. africanum, M. canetti, and M. microti. M. tuberculosis and M. bovis infect both animals and humans. Therefore, differentiation of these two closely related species is very important for epidemiological and management purpose. We undertook the present study to characterize mycobacteria isolated from sputum of known TB patients by conventional methods and further, by multiplex PCR [mPCR] to detect the prevalence of Zoonotic TB [TB caused by M. bovis]. Sputum samples from TB patient were collected from two tertiary care hospitals in Peshawar i.e. Lady Reading Hospital and Hayatabad Medical Complex. All the samples were subjected to Ziehl Neelsen [ZN] stain, culture on Lowenstein Jensen [LJ] and Stone Brink medium, Nitrate reduction test and multiplex PCR. A total of hundred mycobacterial strains were isolated from these samples on the basis of ZN staining, cultural and biochemical methods. Later on, these isolates were subjected to multiplex PCR by using pncATB-1.2 and pncAMT-2 primers specific to M. tuberculosis and JB21, JB22 primers specific to M. bovis. By means of conventional method, these hundred cultures isolates were differentiated into M. tuberculosis [ninety six] and M. bovis [four]. Furthermore, by mPCR, it was determined that out of hundred isolates, ninety-eight were identified as M. tuberculosis and two isolates as M. bovis. This molecular method enables to differentiate M. bovis from M. tuberculosis in human sputum

16.
Medical Forum Monthly. 2015; 26 (11): 27-30
in English | IMEMR | ID: emr-184777

ABSTRACT

Objective: To compare the efficacy of felodipine and propranolol in the treatment of essential hypertension


Study Design: Randomized controlled study


Place and Duration of Study: This study was conducted at Accident and Emergency Department,Bahawal VictoriaHospitalBahawalpurandAnsariPrivateClinicModelTownB,BahawalpurfromMarch2013toMay2013. Materials and Methods: Total 90 patients of mild to moderate essential hypertension both male and female between the ages of 30 to 55 years were enrolled to this study, for 90days patients were randomly divided intothree groups Group I, II and III. Efficiency of felodipine, propranolol and placebo tablets in the treatment essential hypertension wascompared


Results: Felodipine and propranolol both reduces the systolic blood pressure was highly significant [P<0.001] between day 0-15, day 0-30, day 0-45, day 0-60, day 0-75 and day 0-90. The placebo exhibited a non-significant effect on systolic blood pressure.In case of diastolic blood pressure patients treated with felodipine and propranolol the decrease of blood pressure was also significantly [P<0.001] for all time intervals. In placebo administered group the effect of diastolic blood pressure was non-significant at all-time intervals


Conclusion: Result of this study showing that both felodipine and propranolol significantly reduces blood pressure at all time of intervals. In addition felodipine has got an edge on propranolol that it is administered once daily

17.
JLUMHS-Journal of the Liaquat University of Medical Health Sciences. 2015; 14 (1): 12-15
in English | IMEMR | ID: emr-192249

ABSTRACT

OBJECTIVE: The objective of the study is to determine the efficacy of different home prophylactic plaque control methods in patients undergoing orthodontic treatment


MATERIAL AND METHODS: A cross sectional study was conducted at the Department of Orthodontics, Liaquat University of Medical and Health Sciences, Jamshoro and private orthodontic clinics in Hyderabad


The patients fulfilling the inclusion criteria were asked to chew the plaque disclosing tablet [EviplacPastilhas], swish it for 30 seconds, then asked to spit out and asked to wash once with drinking water, plaque score was calculated by using Turesky Modification of Quigley Hein plaque index. Selected patients were given a self-administered questionnaire regarding mechanical means of plaque control


RESULTS: In this study 42% were male and 58% females. The mean age was 19.1 + 2.47 years


The mean plaque score was 4.29+ 1.58 in this study. 62.9% patients were using regular tooth brush and 34.3% were using orthodontic tooth brush. 18.8%, 6.9%, and 3.7% patients were using inter-dental brush, tooth picks and dental floss respectively


The analysis of variance [ANOVA] test revealed no significant differences in different type of brush


CONCLUSION: It is concluded that majority of orthodontic patients were cleaning their teeth either with orthodontic brush or regular tooth brush and very few patients were using interdental aids to control plaque. Both regular and orthodontic brushes were effective in controlling plaque with is statistically insignificant difference

18.
Pakistan Oral and Dental Journal. 2015; 35 (2): 213-215
in English | IMEMR | ID: emr-170046

ABSTRACT

It is generally accepted that an important relationship exists between the arch width and vertical facial morphology. The size and form of the dental arches can have considerable implications on or-thodontic diagnosis and treatment planning. The objective of this study was to determine relationship between inter canine width and vertical facial morphology in a sample of patients seeking orthodontic treatment. This cross sectional comparative study was conducted at out patients department of Orthodontics, KRL Hospital, Islamabad from 11-03-2010 to 11-09-2010. 100 subjects were included in the study. 100 lateral cephalometric radiographs and dental casts were obtained, and traced. On lateral cephalograph, SN-MP angle was measured. On dental casts inter-canine widths were measured. When comparison was made between Inter-canine width with SN-MP angle, the p-value for all the results was significant with a p value <0.05. It was concluded from this study that there is a statistically significant relationship between inter canine widths and vertical facial morphology

19.
Medical Journal of Islamic World Academy of Sciences. 2014; 22 (2): 76-84
in English | IMEMR | ID: emr-152899

ABSTRACT

Many of the herbs and plants, during the past centuries, were described as milk producing. Fennel [Foeniculum vulgare] was one of these herbs in which the medical prescriptions were mentioned by herbal medicine practitioners in various parts of the world. The reason of this study is to shed the lights of the fennel's effect on female rats' mammary glands in the three physiological cases [virgins, pregnant and lactating]. Ninety Norwegian white rats [Sprague-Dawley] were used and divided into four groups treated by fennel plant focusing 5% and 10% of the daily food for a period of 10 and 20 days, two sets of control for each focus for a period of 10 and 20 days, and have took its allocated animal feed and each group includes five animals. Then histological section methods were used with the use of Haematoxylin and eosin stains. It was found there was an increase in the number of alveoli and a slight expansion in the cavities of the alveoli's mammary glands for the virgin and pregnant rats and expansion in the cavities of the alveoli's mammary glands for the lactating rats and a slight increase in the secretory substances for the pregnant and lactating. This means that the seed has given an incentive to increase the growth and the development of the mammary gland in virgin animals as well as the ability of the seed to increase the composition of milk in the duration of the pregnancy and increase the secretion of milk in lactating animals. All these effects were the greatest, biggest and most in all physiological cases in the case of concentration of [10%] for 20 days with the emergence of hyperplasia state

20.
Isra Medical Journal. 2014; 6 (3): 142-145
in English | IMEMR | ID: emr-183499

ABSTRACT

Objective: To assess the diagnostic accuracy of the Alvarado score in acute appendicitis


Study design: A cross sectional study


Place and duration: The study was conducted at the Accident and Emergency Department of KVSS Site Hospital during a period of 12 months from 1 Jan 2012 to 31 Dec 2012


Methodology: Hundred and ten consecutive patients who attended emergency department of KVSS Site Hospital with provisional diagnosis of acute appendicitis were included in this study after informed consent. Alvarado score was recorded and according to the aggregate score, patients were divided into two groups with scores of <5 and >/=5. The clinical diagnoses and operative findings of patients who were subjected to surgery for Alvarado score>/= 5 were compared with their histopathology reports. A self designed questionnaire was used to record relevant data including patients' age, gender, weight, Alvarado score and histopathology


Result: Out of total 110 cases [79 males, 31females], 28.2% [n=31] belonged to Group-A and 71.81% [n=79] belonged to Group-B. Surgical procedures were performed in 98.2% of cases, along with conservative treatment. Final diagnosis by histopathology was confirmed in 71.3% [n=77] cases. The overall negative appendectomy rate was 28.7% [males: 28.2%, females: 30%]. Sensitivity and specificity of Alvarado scoring system was found to be 93.5% and 80.6% respectively. Positive and negative predictive values were 92.3% and 83.3% respectively and accuracy was 89.8%


Conclusion: The Alvarado score is highly effective and non-invasive in the diagnosis of acute appendicitis

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