Clinical and biochemical profile among children admitted with diabetic ketoacidosis and their correlation in prognosis of children admitted in pediatric intensive care unit

Background: The present study aimed to analyse clinical and biochemical profile among children admitted with diabetic ketoacidosis (DKA) and their correlation in prognosis of children admitted in PICU.Methods: The prospective study was conducted in pediatric intensive care unit (PICU) of RNT medical college, Udaipur among 50 DKA children in the age group of (1 month-18 years) for a period of one year after approval of institutional ethics committee. In the study, HbA1c level was measured by automated analyzer method to find out the past 3-month duration of glycemic control. Pearson correlation coefficient was used to find the correlation between serum osmolality and GCS, serum osmolality and duration of hospital stay, correlation between HbA1c levels and GCS, HbA1c levels and duration of hospital stay.Result: The most common presenting complaint was respiratory distress (72%) followed by vomiting (54%), polyuria (34%), polydipsia (24%), pain in abdomen (24%), fever (24%) and polyphagia (4%). There was negative correlation between HbA1c and depressed sensorium, i.e. patients with higher HbA1c levels had poor GCS and it was statistically significant. Patients with higher HbA1c levels had longer duration of hospital stay, although this observation was not statistically significant. Conclusions: The present study concluded that patients presenting with DKA had severe derangement in acid-base parameters. The DKA patients who had higher serum osmolality and poor glycemic control had depressed sensorium at the time of hospital admission and a longer recovery time leading to a prolonged hospital stay, adding to the morbidity associated with the disease.

Impact of Pre and Post-emergence Herbicide Mixtures in Direct Seeded Rice (Oryza sativa L.)

Rice (Oryza sativa L.) is a major source of food for more than half of the world population especially in South and Southeast Asia and Latin America. A field experiment was conducted at Krishi Vigyan Kendra, Yamunanagar district, Haryana during Kharif season of 2022 to study the effect of pre and post-emergence herbicides combinations herbicides in direct-seeded rice under irrigated condition. The experiment was laid out in a Randomized block design with three replications. The weed management treatments were T1: Pendimethalin + pyrazosulfuron T2:Pendimethalin + pyroxasulfone, T3:Pretilachlor + pyrazosulfuron, T4: Fenoxaprop-p-ethyl with safener + ethoxysulfuron,T5: Cyhalofop-butyl + penoxsulam and metsulfuron-methyl + chlorimuron-ethyl, T6.:Triafamone + ethoxysulfuron, T7: Pendimethalin + pyrazosulfuron fb bispyribac-sodium, T8: Pendimethalin + pyroxasulfone fb bispyribac-sodium, T9:Pretilachlor + pyrazosulfuron fb bispyribac-sodium, T10:Pendimethalin fb fenoxaprop-p-ethyl + ethoxysulfuron T11: Weed free, T12:Weedy check. Among herbicides, application T10 (pendimethalin fb fenoxaprop-p-ethyl + ethoxysulfuron) and T5 (cyhalofop-butyl+ penoxsulam and metsulfuron methyl + chlorimuron ethy (pre-mix) was superior over other treatment. Application of pendimethalin fenoxaprop-p-ethyl + ethoxysulfuron reduced 58.89% grassy weed and 50 % BLWs compared to weedy check plot at 60 DAS. Assessment at 60 DAS and at harvest showed that bispyribac-sodium was effective in controlling E. colona and E. crus-galli. However, bispyribac-sodium did not control D. aegyptium and L. chinensis. Fenoxaprop significantly reduced the densities of Dactyloctenium aegyptium, L. chinensis, and Digitaria sanguinalis. Fenoxaprop tank-mix with ethoxysulfuron appeared to be synergistic for the control of E. crusgalli and E. colona, and Cyperus sp. as this tank mixture. Integration of pendimethalin fb fenoxaprop-p-ethyl+ ethoxysulfuron provided control of all type of weeds with highest grain yield (6.1 t ha-1) among different treatments which was statistically at par with weed free (6.3 t ha-1). In economics points of views, the highest B-C ratio (3.03) was obtained in cyhalofop-butyl + penoxsulam + metsulfuron methyl + chlorimuron ethy followed by pendimethalin fb fenoxaprop-p-ethyl + ethoxysulfuron (2.98).

Effects of Herbicides and Nano Urea Mixture on Weeds, Yield Attributes and Yield of Wheat (Triticum aestivum)

Wheat (Triticum aestivum) is second most important staple crop in India after rice. Weeds have emerged as the major biotic stress in wheat. Post-emergence herbicidal combinations are used widely to control the complex weed flora in wheat crops. A field experiment was carried out to study the “Effects of herbicides and nano urea mixture on weeds, yield attributes and yield of wheat (Triticum aestivum)”. The experiment was performed in randomized blocked design with three replications and fourteen treatments in Rabi season 2022-23 at Agronomy Research Farm, CCS Haryana Agricultural University, Hisar. Significantly minimum weed count (1.52 m-2) and dry weight (1.49 g m-2) and maximum weed control efficiency (88.6%) of Phalaris minor and broadleaved weeds (87%) was recorded with application of clodinafop + metribuzin 60 + 210 g ha-1 with nano urea 3 ml L-1 followed by clodinafop + metribuzin 60 + 210 g ha-1 at 90 DAS. In case of yield attributes i.e. number of effective tillers per meter row length (92.5), spike length (11.4 cm), number of grains spike-1 (55.9) and 1000-grain weight (43.8) were higher with application of clodinafop + metribuzin 60 + 210 g ha-1 with nano urea 3 ml L-1 followed by clodinafop + metribuzin 60 + 210 g ha-1. Grain yield (5876 kg ha-1) and B:C (1.94) was recorded higher with application of clodinafop + metribuzin 60 + 210 g ha-1 with nano urea 3 ml L-1 followed by clodinafop + metribuzin 60 + 210 g ha-1 which was significantly higher than weedy check but at par with the weed free treatment.

Road to universal health coverage: unique model of Karnataka, India

With the goal of achieving universal health coverage (UHC), Karnataka, a national leader in healthcare, launched the Arogya Karnataka scheme in March 2018. It was later integrated with the government of India's national health protection scheme Ayushman Bharat Pradhan Mantri Jan Arogya Yojana (AB-PMJAY) to help with financial protection for accessing curative care at the secondary and tertiary levels through collaboration with the public and private sectors. The AB-PMJAY is a rare opportunity to enhance the health of hundreds of millions of Indians and get rid of a significant cause of the country's poverty. The study intends to define the State's distinctive characteristics with relation to AB-PMJAY-ArK and to highlight the State's top initiatives through the scheme. Karnataka has a unique scheme even if it is integrated due to various striking features. The country has an opportunity to address persistent and deeply ingrained issues with governance, quality assurance, and stewardship owing to AB-PMJAY-ArK. The complete approach used by the AB-PMJAY-ArK cell of the department of health and family welfare, government of Karnataka has enhanced the performance of public health institutions and can be adopted as a model by all the Indian States. Access to care, compliance, and timely assistance have all drastically enhanced. This has improved national health indices, but more crucially, it has led to the development of a bigger and stronger public health system, leading the road to UHC.

Study of human knowledge and attitude toward urban birds in Faisalabad city, Pakistan / Estudo do conhecimento humano e da atitude em relação às aves urbanas na cidade de Faisalabad, Paquistão

Abstract Birds are very valuable indicators of species richness and endemic patterns in a specified ecosystem, which eventually help the scientist to measure the environmental degradation. The aim of present study was to know human knowledge and attitude toward urban birds in Faisalabad city, Pakistan. The study conducted in four consecutive months: November 2019 to February 2020. Population of birds was noted from eight residential towns of Faisalabad city, data were collected through questionnaire. Faisalabad has a reasonably large population of birds and present data show that, there is a significant difference between favorite bird of residential areas and institutions. The pigeon received the most likeness in bird population among residential area residents, while the myna received the least. The most popular bird in Faisalabad institutions was the sparrow, while the least popular bird was the common myna. Bird adaptation percentage of residential areas and institutional areas of Faisalabad was the highest for parrot and sparrow respectively. People in residential areas and institutions, on the other hand, adapted least to common myna. It is concluded that people of the study area like birds and offered food and high population of birds are present in study area.

Resumo Os pássaros são indicadores muito valiosos da riqueza de espécies e padrões endêmicos em um determinado ecossistema, o que acaba ajudando o cientista a medir a degradação ambiental. O objetivo do presente estudo foi conhecer o conhecimento humano e a atitude em relação às aves urbanas na cidade de Faisalabad, Paquistão. O estudo foi conduzido em quatro meses consecutivos: novembro de 2019 a fevereiro de 2020. A população de pássaros foi observada em oito cidades residenciais da cidade de Faisalabad, os dados foram coletados por meio de questionário. Faisalabad tem uma população razoavelmente grande de pássaros, e os dados atuais mostram que há uma diferença significativa entre as aves favoritas de áreas residenciais e instituições. O pombo recebeu mais semelhanças na população de pássaros entre os residentes de áreas residenciais, enquanto o myna recebeu menos. A ave mais popular nas instituições de Faisalabad era o pardal, enquanto a ave menos popular era o myna comum. A porcentagem de adaptação de pássaros em áreas residenciais e institucionais de Faisalabad foi a mais alta para papagaios e pardais, respectivamente. As pessoas em áreas residenciais e instituições, por outro lado, se adaptaram menos ao myna comum. Conclui-se que pessoas da área de estudo como pássaros e alimentos oferecidos e alta população de pássaros estão presentes na área de estudo.

Study of human knowledge and attitude toward urban birds in Faisalabad city, Pakistan / Estudo do conhecimento humano e da atitude em relação às aves urbanas na cidade de Faisalabad, Paquistão

Birds are very valuable indicators of species richness and endemic patterns in a specified ecosystem, which eventually help the scientist to measure the environmental degradation. The aim of present study was to know human knowledge and attitude toward urban birds in Faisalabad city, Pakistan. The study conducted in four consecutive months: November 2019 to February 2020. Population of birds was noted from eight residential towns of Faisalabad city, data were collected through questionnaire. Faisalabad has a reasonably large population of birds and present data show that, there is a significant difference between favorite bird of residential areas and institutions. The pigeon received the most likeness in bird population among residential area residents, while the myna received the least. The most popular bird in Faisalabad institutions was the sparrow, while the least popular bird was the common myna. Bird adaptation percentage of residential areas and institutional areas of Faisalabad was the highest for parrot and sparrow respectively. People in residential areas and institutions, on the other hand, adapted least to common myna. It is concluded that people of the study area like birds and offered food and high population of birds are present in study area.

Os pássaros são indicadores muito valiosos da riqueza de espécies e padrões endêmicos em um determinado ecossistema, o que acaba ajudando o cientista a medir a degradação ambiental. O objetivo do presente estudo foi conhecer o conhecimento humano e a atitude em relação às aves urbanas na cidade de Faisalabad, Paquistão. O estudo foi conduzido em quatro meses consecutivos: novembro de 2019 a fevereiro de 2020. A população de pássaros foi observada em oito cidades residenciais da cidade de Faisalabad, os dados foram coletados por meio de questionário. Faisalabad tem uma população razoavelmente grande de pássaros, e os dados atuais mostram que há uma diferença significativa entre as aves favoritas de áreas residenciais e instituições. O pombo recebeu mais semelhanças na população de pássaros entre os residentes de áreas residenciais, enquanto o myna recebeu menos. A ave mais popular nas instituições de Faisalabad era o pardal, enquanto a ave menos popular era o myna comum. A porcentagem de adaptação de pássaros em áreas residenciais e institucionais de Faisalabad foi a mais alta para papagaios e pardais, respectivamente. As pessoas em áreas residenciais e instituições, por outro lado, se adaptaram menos ao myna comum. Conclui-se que pessoas da área de estudo como pássaros e alimentos oferecidos e alta população de pássaros estão presentes na área de estudo.

Study of human knowledge and attitude toward urban birds in Faisalabad city, Pakistan

Abstract Birds are very valuable indicators of species richness and endemic patterns in a specified ecosystem, which eventually help the scientist to measure the environmental degradation. The aim of present study was to know human knowledge and attitude toward urban birds in Faisalabad city, Pakistan. The study conducted in four consecutive months: November 2019 to February 2020. Population of birds was noted from eight residential towns of Faisalabad city, data were collected through questionnaire. Faisalabad has a reasonably large population of birds and present data show that, there is a significant difference between favorite bird of residential areas and institutions. The pigeon received the most likeness in bird population among residential area residents, while the myna received the least. The most popular bird in Faisalabad institutions was the sparrow, while the least popular bird was the common myna. Bird adaptation percentage of residential areas and institutional areas of Faisalabad was the highest for parrot and sparrow respectively. People in residential areas and institutions, on the other hand, adapted least to common myna. It is concluded that people of the study area like birds and offered food and high population of birds are present in study area.

Resumo Os pássaros são indicadores muito valiosos da riqueza de espécies e padrões endêmicos em um determinado ecossistema, o que acaba ajudando o cientista a medir a degradação ambiental. O objetivo do presente estudo foi conhecer o conhecimento humano e a atitude em relação às aves urbanas na cidade de Faisalabad, Paquistão. O estudo foi conduzido em quatro meses consecutivos: novembro de 2019 a fevereiro de 2020. A população de pássaros foi observada em oito cidades residenciais da cidade de Faisalabad, os dados foram coletados por meio de questionário. Faisalabad tem uma população razoavelmente grande de pássaros, e os dados atuais mostram que há uma diferença significativa entre as aves favoritas de áreas residenciais e instituições. O pombo recebeu mais semelhanças na população de pássaros entre os residentes de áreas residenciais, enquanto o myna recebeu menos. A ave mais popular nas instituições de Faisalabad era o pardal, enquanto a ave menos popular era o myna comum. A porcentagem de adaptação de pássaros em áreas residenciais e institucionais de Faisalabad foi a mais alta para papagaios e pardais, respectivamente. As pessoas em áreas residenciais e instituições, por outro lado, se adaptaram menos ao myna comum. Conclui-se que pessoas da área de estudo como pássaros e alimentos oferecidos e alta população de pássaros estão presentes na área de estudo.

Comparative Study of DENTA Scan and Radiography for Pre-Operative Assessment of Dental Implants

Background: Dental implant placement has become a very common procedure in the modern era. Pre operative assessment is of immense value to ensure the long term stability of dental implants. Aim: The aim of our study was to compare the efficacy of Dental CT with radiography in planning implant surgery and pre-operative evaluation prior to implant placement. Methods: We conducted a hospital based prospective study in which patients for dental implant placement were evaluated with Dental CT and Radiography. Results: The radiographs overestimated the height of the alveolar ridge in majority of the pre implant cases as compared to Dental CT. For bucco-lingual analysis Dental CT provided an overwhelming advantage over Dental Radiography and clinical examination. The angle of alveolar ridge could not be assessed on radiographs whereas could be accurately estimated on Dental CT. Bone density of the implant site could be quantitatively determined on Dental CT whereas could not be determined on Radiographs. Conclusions: We concluded that Dental CT yields significantly better information than radiographs regarding pre-operative assessment of dental implants.

Biochemical effects of Nigella sativa L seeds in diabetic rats.

Oral administration of ethanol extract of N. sativa seeds (300 mg/kg body weight/day) to streptozotocin induced diabetic rats for 30 days significantly reduced the elevated levels of blood glucose, lipids, plasma insulin and improved altered levels of lipid peroxidation products (TBARS and hydroperoxides) and antioxidant enzymes like catalase, superoxide dismutase, reduced glutathione and glutathione peroxidase in liver and kidney. The results confirm the antidiabetic activity of N. sativa seeds extract and suggest that because of its antioxidant effects its administration may be useful in controlling the diabetic complications in experimental diabetic rats.

Working conditions and health among employees at information technology--enabled services: a review of current evidence.

Workers in information technology (IT)-enabled services like business process outsourcing and call centers working with visual display units are reported to have various health and psycho-social disorders. Evidence from previously published studies in peer- reviewed journals and internet sources were examined to explore health disorders and psycho-social problems among personnel employed in IT-based services, for a systematic review on the topic. In addition, authors executed a questionnaire- based pilot study. The available literature and the pilot study, both suggest health disorders and psychosocial problems among workers of business process outsourcing. The details are discussed in the review.

A novel locus for X-linked retinitis pigmentosa

<p><b>INTRODUCTION</b>Retinitis pigmentosa (RP) is the most prevalent group of inherited retinopathies and demonstrates considerable clinical and genetic heterogeneity, with wide variations in disease severity, progression, and gene involvement. We studied a large family with RP to determine the pattern of inheritance and to identify the disease-causing gene/locus.</p><p><b>MATERIALS AND METHODS</b>Ophthalmic examination was performed on 35 family members to identify affected individuals and carriers and to characterise the disease phenotype. Genetic linkage analysis was performed using short tandem repeat (STR) polymorphic markers encompassing the known loci for Xlinked RP (xlRP) including RP2, RP3, RP6, RP23, and RP24. Mutation screening was performed by direct sequencing of PCR-amplified genomic DNA of the RP2 and RPGR genes of the affected individuals.</p><p><b>RESULTS</b>A highly penetrant, X-linked form of RP was observed in this family. Age of onset was from 5 to 8 years and visual acuity ranged from 20/25 in children to light perception in older adults. Linkage analysis and direct sequencing showed that no known loci/genes were associated with the phenotype in this kindred.</p><p><b>CONCLUSION</b>A novel disease gene locus/loci is responsible for the xlRP phenotype in this family.</p>

Effects of tea consumption on thiamine status and nerve conduction in Pakistani people

It is known that tea contains some polyphenolic antithiamin factors and tea consumption causes thiamine deficiency in human beings. The effect of tea drinking on the thiamine status and nerve conduction in Pakistani people was investigated. Thiamine status was measured as thiamine pyrophosphate effects [TPPE] on erythrocyte transketolase activity [ETKA] and the results were expressed as TPPE%. Nerve conduction was measured by conventional electromyographic [EMG] methods. TPPE% values were increased to deficient levels by drinking tea and decreased to the normal values by thiamine supplement. There was no significant alteration in the nerve conduction of the peoples under study, by tea consumption within our study period

Study of antimutagenic and mutagenic effect of different chemicals on clinically isolated strains of pseudomonas aeruginosa

This project was undertaken to study the effect of twelve different compounds to test their antimutagenic and ii mutagenic activity against clinically isolated strains of Pseudomonas aeruginosa. The effect of these compound was estimated by counting the number of rifampicin resistant colonies growing in a particular time in a it compound. The results were interpreted by plotting graphs between lOg N/No [Rif R Colonies/ml] and time to estimate the forward mutation rate. The results revealed that Acridine, Basic fuchsin, Caffeine, Cyclohexamide, Zehidium bromide and Histidine probably have an antimutagenic effect, while [steine, Folic acid, Ethyl-methane. ulphonate, Manganous Chloride and N-nitrosodietylamine acted as mutagen. E.coli was used as control through out the study

Pharmacodynamic studies on Polypodium vulgare (Linn.).

Aqueous extract of the root of P. vulgare (PV) produced CNS depressant effect. It decreased the spontaneous motor activity, prolonged the pentobarbitone induced hypnosis, reduced body temperature and increased the reaction time to pain stimuli. PV also caused prevention against supramaximal electroshock and pentylenetetrazol induced seizures. PV showed a positive inotropic and chronotropic effect on perfused frog heart and caused hypotension and tachycardia in anaesthetised dogs. The effects were blocked by propranolol. PV produced dose dependent inhibition of contractions of rabbit small intestine and the effect was blocked by propranolol. PV appears to possess CNS depressant and beta-adrenoceptor agonistic activities.