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Braz. oral res. (Online) ; 35: e090, 2021. tab
Article in English | LILACS, BBO | ID: biblio-1285721


Abstract The present cross-sectional case-control study aimed to determine if there is an association between specific oral behaviors, sleep bruxism (SB), awake bruxism (AB), and painful temporomandibular joint (TMJ) clicking. Ninety individuals were dived into three groups; Group 1 (n = 30): painful TMJ clicking; Group 2 (n = 30): painless TMJ clicking; and Group 3 (n = 30): control group. The following clinical data were studied: oral behaviors (unilateral chewing, gum chewing, nail biting, foreign objects biting, leaning with jaw against the hand, and sleeping in a position that pressures the jaw), SB, AB (including the frequency in 10 days, evaluated by ecological momentary assessment), and malocclusions investigated based on clinical inspections (anterior open bite, posterior cross-bite, abnormal overbite/overjet, occlusal guidance, mediotrusive and/or laterotrusive interferences, retruded contact position to maximum intercuspation slide, missing posterior teeth). All statistical tests (Kolmogorov-Smirnov, chi-square, and one-way ANOVA) were performed with a 5% significance level. Group 1 had the highest frequency of and a significant association with leaning with jaw in the hand, sleeping position that pressures the jaw, gum chewing, nail biting, and AB (p<0.05). Gum chewing, nail biting, and AB were associated with Group 2 only when compared to Group 3 (p<0.05). No significant difference among groups was found for other behaviors (unilateral chewing and foreign objects biting), SB, and all malocclusions (p>0.05). It can be concluded that patients with painful TMJ clicking had a higher frequency of and a significant association with some specific harmful behaviors and AB.

Humans , Bruxism , Sleep Bruxism , Malocclusion , Temporomandibular Joint , Case-Control Studies , Cross-Sectional Studies
J. appl. oral sci ; 29: e20200952, 2021. tab, graf
Article in English | LILACS | ID: biblio-1250186


Abstract Stress is a contributing factor to painful temporomandibular disorders (TMD). Nevertheless, the underpinnings of this relationship are not fully understood. Objective To investigate the effects of acute mental stress on conditioned pain modulation (CPM) in TMD patients compared with healthy individuals. Methodology Twenty women with chronic myofascial TMD diagnosed according to the RDC/TMD and 20 age-matched healthy women had the CPM assessed before and after a stressful task using the Paced Auditory Serial Addition Task (PASAT) in a single session. Subjective stress response was assessed with the aid of visual analog scale (VAS). Pressure pain threshold (PPT) on masseter muscle was the test stimulus (TS) and immersion of the participant's hand on hot water was the conditioning stimulus (CS) - CPM-sequential paradigm. Results Healthy individuals reported PASAT are more stressful when compared with TMD patients and the stress task did not affect the CPM in neither group. Nonetheless, a negative correlation was observed between change in CPM and change in TS from baseline to post-stress session, which indicates that the greater the increase in PPT after the stress task, the greater was the decrease in CPM magnitude. The correlation was strong for healthy controls (r=- 0.72, p<0.001) and moderate for TMD patients (r=- 0.44, p=0.047). Conclusions The correlation between the change in CPM and the TS change following the stress task may possibly indicate an overlapping pathway between stress-induced analgesia/hyperalgesia and descending pain inhibition.

Humans , Female , Temporomandibular Joint Disorders , Pain Threshold , Pain , Stress, Psychological , Pain Measurement
J. appl. oral sci ; 28: e20190407, 2020. tab
Article in English | LILACS, BBO | ID: biblio-1090779


Abstract This study aimed to evaluate whether the presence of awake bruxism was associated with temporomandibular dysfunction symptoms, pain threshold at pressure, pain vigilance, oral health-related quality of life (OHRQoL), and anxiety and depression symptoms in patients undergoing orthodontic treatment. Methodology This observational study followed patients who had started receiving orthodontic treatment for six months. The following variables were measured three times (at baseline, one month, and six months): pressure pain threshold (PPT) in the right and left masseter, anterior temporalis, and temporomandibular joint (TMJ), and right forearm; pain vigilance and awareness questionnaire; and shortened form of the oral health impact profile (OHIP-14). Anxiety and depression symptoms were measured using the Beck anxiety inventory and the Beck depression inventory, respectively. The patients were divided into two main groups according to the presence (n=56) and absence (n=58) of possible awake bruxism. The multi-way analysis of variance (ANOVA) was applied on the date (p=0.050). Results TMJ and/or muscle pain were not observed in both groups. Time, sex, age group, and awake bruxism did not affect the PPT in the masticatory muscles and pain vigilance (p>0.050). However, the primary effect of awake bruxism was observed when anxiety (ANOVA: F=8.61, p=0.004) and depression (ANOVA: F=6.48, p=0.012) levels were higher and the OHRQoL was lower (ANOVA: F=8.61, p=0.004). Conclusion The patients with self-reported awake bruxism undergoing an orthodontic treatment did not develop TMJ/masticatory muscle pain. The self-reported awake bruxism is associated with higher anxiety and depression levels and a poorer OHRQoL in patients during the orthodontic treatment.

Humans , Male , Female , Adolescent , Adult , Middle Aged , Anxiety/physiopathology , Quality of Life/psychology , Bruxism/psychology , Pain Threshold/psychology , Depression/physiopathology , Self Report , Psychiatric Status Rating Scales , Psychometrics , Severity of Illness Index , Bruxism/physiopathology , Bruxism/therapy , Temporomandibular Joint Disorders/physiopathology , Temporomandibular Joint Disorders/psychology , Analysis of Variance , Pain Threshold/physiology , Statistics, Nonparametric , Myalgia
J. appl. oral sci ; 27: e20180433, 2019. graf
Article in English | LILACS, BBO | ID: biblio-984575


Abstract Disc displacement with reduction (DDWR) is one of the most common intra-articular disorders of the temporomandibular joint (TMJ). Factors related to the etiology, progression and treatment of such condition is still a subject of discussion. This literature review aimed to address etiology, development, related factors, diagnosis, natural course, and treatment of DDWR. A non-systematic search was conducted within PubMed, Scopus, SciELO, Medline, LILACS and Science Direct using the Medical Subjective Headings (MeSH) terms "temporomandibular disorders", "temporomandibular joint", "disc displacement" and "disc displacement with reduction". No time restriction was applied. Literature reviews, systematic reviews, meta-analysis and clinical trials were included. DDWR is usually asymptomatic and requires no treatment, since the TMJ structures adapt very well and painlessly to different disc positions. Yet, long-term studies have shown the favorable progression of this condition, with no pain and/or jaw locking occurring in most of the patients.

Humans , Temporomandibular Joint Disorders/physiopathology , Temporomandibular Joint Disorders/therapy , Temporomandibular Joint Disc/physiopathology , Joint Dislocations/physiopathology , Joint Dislocations/therapy , Magnetic Resonance Imaging , Temporomandibular Joint Disorders/diagnosis , Temporomandibular Joint Disorders/etiology , Disease Progression , Joint Dislocations/diagnosis , Joint Dislocations/etiology
J. appl. oral sci ; 25(2): 112-120, Mar.-Apr. 2017. tab, graf
Article in English | LILACS, BBO | ID: biblio-841174


Abstract Studies to assess the effects of therapies on pain and masticatory muscle function are scarce. Objective To investigate the short-term effect of transcutaneous electrical nerve stimulation (TENS) by examining pain intensity, pressure pain threshold (PPT) and electromyography (EMG) activity in patients with temporomandibular disorder (TMD). Material and Methods Forty patients with myofascial TMD were enrolled in this randomized placebo-controlled trial and were divided into two groups: active (n=20) and placebo (n=20) TENS. Outcome variables assessed at baseline (T0), immediately after (T2) and 48 hours after treatment (T1) were: pain intensity with the aid of a visual analogue scale (VAS); PPT of masticatory and cervical structures; EMG activity during mandibular rest position (MR), maximal voluntary contraction (MVC) and habitual chewing (HC). Two-way ANOVA for repeated measures was applied to the data and the significance level was set at 5%. Results There was a decrease in the VAS values at T1 and T2 when compared with T0 values in the active TENS group (p<0.050). The PPT between-group differences were significant at T1 assessment of the anterior temporalis and sternocleidomastoid (SCM) and T2 for the masseter and the SCM (p<0.050). A significant EMG activity reduction of the masseter and anterior temporalis was presented in the active TENS during MR at T1 assessment when compared with T0 (p<0.050). The EMG activity of the anterior temporalis was significantly higher in the active TENS during MVC at T1 and T2 when compared with placebo (p<0.050). The EMG activity of the masseter and anterior temporalis muscle was significantly higher in the active TENS during HC at T1 when compared with placebo (p<0.050). Conclusions The short-term therapeutic effects of TENS are superior to those of the placebo, because of reported facial pain, deep pain sensitivity and masticatory muscle EMG activity improvement.

Humans , Male , Female , Adult , Young Adult , Temporal Muscle/physiopathology , Facial Pain/physiopathology , Facial Pain/therapy , Temporomandibular Joint Disorders/physiopathology , Temporomandibular Joint Disorders/therapy , Transcutaneous Electric Nerve Stimulation/methods , Masseter Muscle/physiopathology , Time Factors , Pain Measurement , Placebo Effect , Reproducibility of Results , Analysis of Variance , Treatment Outcome , Pain Threshold , Electromyography
J. appl. oral sci ; 23(6): 555-561, Nov.-Dec. 2015. tab, graf
Article in English | LILACS, BBO | ID: lil-769820


ABSTRACT Low pressure Pain Threshold (PPT) is considered a risk factor for Temporomandibular Disorders (TMD) and is influenced by psychological variables. Objectives To correlate deep pain sensitivity of masticatory muscles with prosthetic factors and Oral-Health-Related Quality of Life (OHRQoL) in completely edentulous subjects. Material and Methods A total of 29 complete denture wearers were recruited. The variables were: a) Pressure Pain Threshold (PPT) of the masseter and temporalis; b) retention, stability, and tooth wear of dentures; c) Vertical Dimension of Occlusion (VDO); d) Oral Health Impact Profile (OHIP) adapted to orofacial pain. The Kolmogorov-Smirnov test, the Pearson Product-Moment correlation coefficient, the Spearman Rank correlation coefficient, the Point-Biserial correlation coefficient, and the Bonferroni correction (α=1%) were applied to the data. Results The mean age (standard deviation) of the participants was of 70.1 years (9.5) and 82% of them were females. There were no significant correlations with prosthetic factors, but significant negative correlations were found between the OHIP and the PPT of the anterior temporalis (r=-0.50, 95% CI-0.73 to 0.17, p=0.005). Discussion The deep pain sensitivity of masticatory muscles in complete dentures wearers is associated with OHRQoL, but not with prosthetic factors.

Humans , Male , Female , Middle Aged , Aged , Denture, Complete/psychology , Masticatory Muscles/physiopathology , Oral Health , Pain Threshold/physiology , Pain Threshold/psychology , Quality of Life/psychology , Cross-Sectional Studies , Patient Satisfaction , Pilot Projects , Psychometrics , Reference Values , Risk Factors , Sickness Impact Profile , Statistics, Nonparametric , Temporomandibular Joint Disorders/physiopathology , Temporomandibular Joint Disorders/psychology , Vertical Dimension
Arq. bras. cardiol ; 105(2): 160-167, Aug. 2015. tab, ilus
Article in English | LILACS | ID: lil-758002


AbstractBackground:Hypertension is a public health problem and increases the incidence of cardiovascular diseases.Objective:To evaluate the effects of a resistance exercise session on the contractile and relaxing mechanisms of vascular smooth muscle in mesenteric arteries of NG-nitro L-arginine methyl ester (L-NAME)-induced hypertensive rats.Methods:Wistar rats were divided into three groups: control (C), hypertensive (H), and exercised hypertensive (EH). Hypertension was induced by administration of 20 mg/kg of L-NAME for 7 days prior to experimental protocols. The resistance exercise protocol consisted of 10 sets of 10 repetitions and intensity of 40% of one repetition maximum. The reactivity of vascular smooth muscle was evaluated by concentration‑response curves to phenylephrine (PHEN), potassium chloride (KCl) and sodium nitroprusside (SNP).Results:Rats treated with L-NAME showed an increase (p < 0.001) in systolic blood pressure (SBP), diastolic blood pressure (DBP) and mean arterial pressure (MAP) compared to the initial period of induction. No difference in PHEN sensitivity was observed between groups H and EH. Acute resistance exercise reduced (p < 0.001) the contractile response induced by KCl at concentrations of 40 and 60 mM in group EH. Greater (p < 0.01) smooth muscle sensitivity to NPS was observed in group EH as compared to group H.Conclusion:One resistance exercise session reduces the contractile response induced by KCl in addition to increasing the sensitivity of smooth muscle to NO in mesenteric arteries of hypertensive rats.

ResumoFundamento:A hipertensão é um problema de saúde pública e faz aumentar a incidência das doenças cardiovasculares.Objetivo:Avaliar os efeitos de uma sessão de exercício resistido sobre os mecanismos contráteis e relaxantes do músculo liso vascular em artéria mesentérica de ratos hipertensos induzidos por L-NAME.Métodos:Ratos Wistar foram divididos em três grupos: Controle (C), Hipertenso (H) e Hipertenso Exercitado (HE). A hipertensão foi induzida pela administração de 20 mg/kg de NG-nitro L-arginina metil éster (L-NAME) durante sete dias antes dos protocolos experimentais. O protocolo de exercício resistido consistiu em dez séries de dez repetições e intensidade de 40% de uma repetição máxima. A reatividade do músculo liso vascular foi avaliada através de curvas concentração-resposta para a fenilefrina (FEN), cloreto de potássio (KCl) e nitroprussiato de sódio (NPS).Resultados:Os ratos tratados com L-NAME apresentaram aumento (p < 0,001) da Pressão Arterial Sistólica (PAS), da Pressão Arterial Diastólica (PAD) e da Pressão Arterial Média (PAM) quando comparados ao período inicial da indução. Não foi observada diferença na sensibilidade da FEN entre os grupos H e HE. O exercício resistido agudo reduziu (p < 0,001) a resposta contrátil induzida pelo KCl nas concentrações de 40 e 60 mM do grupo HE quando comparado ao grupo H. Foi observado maior (p < 0,01) sensibilidade do músculo liso ao NPS no grupo HE quando comparado ao grupo H.Conclusão:Uma sessão de exercício resistido reduz as respostas contráteis induzidas pelo KCl, além de aumentar a sensibilidade do músculo liso ao NO em artéria mesentérica de ratos hipertensos.

Animals , Exercise Tolerance/physiology , Hypertension/physiopathology , Muscle, Smooth, Vascular/physiopathology , Physical Conditioning, Animal/physiology , Body Weight , Blood Pressure/drug effects , Blood Pressure/physiology , Enzyme Inhibitors/pharmacology , Mesenteric Arteries/physiopathology , Muscle Contraction/drug effects , Muscle Contraction/physiology , Muscle, Smooth, Vascular/drug effects , NG-Nitroarginine Methyl Ester/pharmacology , Nitroprusside/analysis , Phenylephrine/analysis , Potassium Chloride/analysis , Rats, Wistar , Time Factors
J. appl. oral sci ; 23(2): 129-134, Mar-Apr/2015. tab, graf
Article in English | LILACS, BBO | ID: lil-746545


OBJECTIVES: This cross-sectional study aimed to evaluate the influence of Primary Headache (PH) on efficacy of a Temporomandibular Disorders (TMD) conservative therapy and its association with the presence of self-reported parafunctional habits. SAMPLE AND METHODS: Sample was composed of 400 medical records, divided into four groups: I) Muscular TMD (n=64); II) Muscular TMD+PH (n=48); III) Muscular TMD+Articular TMD (n=173); IV) Muscular TMD+Articular TMD+PH (n=115). All groups had undergone a TMD therapy for three months with a stabilization appliance and counseling for habits and behavioral changes, with no specific headache management. Current pain intensity and existence or not of self-reported bruxism were assessed. Repeated measures ANOVA and Chi-Square test followed by Odds were used for statistical analysis, with a significance level of 5%. RESULTS: results of this study showed that: (1) A conservative therapy with stabilization appliance and counseling for habits and behavioral changes was effective in the TMD pain relief; (2) Groups with an additional diagnosis of PH had worsened the pain improvement significantly; and (3) no association between the presence of self-reported bruxism and PH was found. CONCLUSIONS: this study could elucidate the important effect that headache may have on the TMD management. .

Humans , Animals , Female , Pregnancy , Food Contamination/analysis , Mercury/analysis , Seafood/analysis , Selenium/analysis , Diet , Fishes , Mercury/blood , Methylmercury Compounds/analysis , Quality Control , Risk Factors , Sharks , Taiwan , United States
Rev. dor ; 16(1): 53-59, Jan-Mar/2015. tab, graf
Article in English | LILACS-Express | LILACS | ID: lil-742942


BACKGROUND AND OBJECTIVES: For most cases, temporomandibular disorders should be treated by a non-invasive, interdisciplinary and integrative process. In traditional Chinese medicine, acupuncture is an excellent tool aiming at treating and healing this disease. This study was a critical literature review to observe the efficacy of traditional Chinese acupuncture to treat muscular temporomandibular disorders and to identify primary acupoints. CONTENTS: Pubmed, LILACS, Scielo and Cochrane databases were queried to identify scientific articles relevant for the study. Articles were selected from January 2000 to May 2013. A total of 125 articles were found and 21 were included. Acupuncture treatment alone or as additional therapy, or even compared to other techniques, was superior and effective to improve pain and function of patients with temporomandibular disorders and most commonly used acupoints were IG4, E6, E7 and F3. CONCLUSION: This study has shown that acupuncture is a technique recommended by national and international literature to treat muscular temporomandibular disorders, promoting pain relief and/or total intensity, improvement of joint movements and oral function and decrease of masticatory muscles hyperactivity. .

JUSTIFICATIVA E OBJETIVOS: Na grande maioria dos casos, o tratamento das disfunções temporomandibulares deve ser um processo não invasivo, interdisciplinar e integrativo. Dentro da medicina tradicional chinesa, a acupuntura é uma ótima ferramenta que visa a terapia e cura dessas doenças. O objetivo deste estudo foi conduzir uma revisão crítica da literatura para verificar a eficácia da acupuntura tradicional chinesa no tratamento da disfunção temporomandibular do tipo muscular, bem como identificar os principais acupontos. CONTEÚDO: Foi realizada uma pesquisa nas bases de dados Pubmed, LILACS, Scielo e Cochrane para identificar artigos científicos relevantes para o estudo. Os artigos foram selecionados no período de janeiro de 2000 a maio de 2013. Encontrou-se um total de 125 artigos, sendo que 21 foram incluídos. O tratamento de acupuntura isolado ou como terapia complementar, ou ainda comparado com outras técnicas, se mostrou superior e eficiente na melhora da dor e da função de pacientes com disfunção temporomandibular, e os pontos de acupuntura mais citados foram IG4, E6, E7 e F3. CONCLUSÃO: Este estudo demonstrou que a acupuntura é uma técnica recomendada pela literatura nacional e internacional para o tratamento de disfunções temporomandibulares de origem muscular, promovendo alivio e/ou redução total da intensidade dolorosa, melhora nos movimentos mandibulares e na função oral e diminuição da hiperatividade muscular dos músculos da mastigação. .

Rev. dor ; 16(1): 22-26, Jan-Mar/2015. graf
Article in English | LILACS-Express | LILACS | ID: lil-742948


BACKGROUND AND OBJECTIVES: Physical evaluation of temporomandibular disorder patients commonly includes evaluation of pain response to muscular and articular palpation and there is a considerable uncertainty of how self-reported pain intensity relates to Pressure Pain Threshold obtained in an algometry exam. The present study aimed at determining whether pain intensity is associated to Pressure Pain Threshold in temporomandibular disorder patients. METHODS: Eighty arthralgia patients and one hundred and thirty masticatory myofascial pain patients participated in this study. Pain intensity was recorded with visual analog scale. Pressure Pain Threshold was measured using a pressure algometer. Pressure was applied bilaterally on the temporomandibular joint in arthralgia patients and masseter and anterior temporalis muscles. Pearson correlation coefficient (r) was calculated to determine the strength of the relationship between pain intensity and the lowest Pressure Pain Threshold value in each site. RESULTS: The correlation between all pain intensity and Pressure Pain Threshold values was statistically weak. Correlations between pain intensity and joint Pressure Pain Threshold (r=- 0.236; p=0.035) in the arthralgia group and pain intensity and masseter’s Pressure Pain Threshold (r=-0.312; p<0.001) and between pain intensity and anterior temporalis Pressure Pain Threshold (r=-0.240; p=0.006) were statistically significant. CONCLUSION: The weak correlation between pain intensity and Pressure Pain Threshold suggests that other factors are clearly important in explaining the pain experience of temporomandibular disorder patients, including the contribution of central nervous system nociceptive processes and psychological variables to the maintenance of chronic pain. .

JUSTIFICATIVA E OBJETIVOS: A avaliação clínica de pacientes com disfunção temporomandibular inclui a avaliação da resposta dolorosa à palpação muscular e articular e existe uma incerteza sobre como a intensidade da dor relatada pelo paciente se relaciona com o limiar de dor à pressão obtido com exame de algometria. O presente estudo objetivou determinar se há uma associação entre essas duas variáveis. MÉTODOS: Oitenta pacientes com artralgia e 130 com dor miofascial mastigatória participaram deste estudo. A intensidade de dor foi aferida com a escala visual analógica. O limiar de dor à pressão foi aferido utilizando o algômetro. A pressão foi aplicada bilateralmente na articulação temporomandibular nos pacientes com artralgia e nos músculos masseter e temporal anterior. O teste utilizado na análise estatística foi o coeficiente de correlação de Pearson (r) para determinar a força da correlação entre intensidade de dor e o menor valor de limiar de dor à pressão. RESULTADOS: As correlações entre os valores de intensidade de dor e limiar de dor à pressão foram estatisticamente fracas. As correlações entre intensidade de dor e limiar de dor à pressão na articulação temporomandibular (r=-0,236; p=0,03), no masseter (r=-0,312; p<0,001) e no temporal anterior (r=-0,240; p=0,006) foram estatisticamente significantes. CONCLUSÃO: A baixa correlação entre intensidade de dor e limiar de dor à pressão sugere que outros fatores possam ser claramente importantes para explicar a experiência dolorosa de pacientes com disfunção temporomandibular, incluindo a contribuição do processo nociceptivo no sistema nervoso central e as variáveis psicossociais para a manutenção da dor crônica. .

Braz. oral res. (Online) ; 29(1): 1-7, 2015. tab, ilus
Article in English | LILACS | ID: lil-777215


A systematic review was conducted to identify reliable somatosensory evaluation methods for atypical odontalgia (AO) patients. The computerized search included the main databases (MEDLINE, EMBASE, and Cochrane Library). The studies included used the following quantitative sensory testing (QST) methods: mechanical detection threshold (MDT), mechanical pain threshold (MPT) (pinprick), pressure pain threshold (PPT), dynamic mechanical allodynia with a cotton swab (DMA1) or a brush (DMA2), warm detection threshold (WDT), cold detection threshold (CDT), heat pain threshold (HPT), cold pain detection (CPT), and/or wind-up ratio (WUR). The publications meeting the inclusion criteria revealed that only mechanical allodynia tests (DMA1, DMA2, and WUR) were significantly higher and pain threshold tests to heat stimulation (HPT) were significantly lower in the affected side, compared with the contralateral side, in AO patients; however, for MDT, MPT, PPT, CDT, and WDT, the results were not significant. These data support the presence of central sensitization features, such as allodynia and temporal summation. In contrast, considerable inconsistencies between studies were found when AO patients were compared with healthy subjects. In clinical settings, the most reliable evaluation method for AO in patients with persistent idiopathic facial pain would be intraindividual assessments using HPT or mechanical allodynia tests.

Adult , Female , Humans , Male , Middle Aged , Pain Measurement/methods , Pain Threshold/physiology , Toothache/physiopathology , Facial Pain/physiopathology , Physical Stimulation , Randomized Controlled Trials as Topic
ImplantNews ; 12(2): 174-179, 2015. tab
Article in Portuguese | LILACS | ID: lil-757857


Esta revisão de literatura avaliou a relação entre as dores neuropáticas orofaciais e as lesões neuronais associadas à instalação de implantes dentários, tendo como foco os aspectos clínicos, preventivos e suas opções terapêuticas. Material e métodos: uma revisão de literatura foi realizada tendo como referência as bases de dados PubMed e SciELO. Apenas estudos clínicos publicados entre os anos de 1993 e 2013 foram analisados. Resultados: as ferramentas de busca permitiram a seleção de 18 trabalhos, sendo: seis relatos de casos clínicos, sete estudos observacionais, um ensaio clínico randomizado e quatro revisões da literatura. Grande parte dos trabalhos revelou que as lesões neuronais relacionadas às cirurgias para instalação de implantes são de caráter transitório. Conclusão: o reconhecimento precoce dos sinais e sintomas de lesões neuronais, bem como o acompanhamento do progresso na regeneração nervosa, representam boas práticas clínicas que devem ser aplicadas com o objetivo de evitar a cronificação da lesão...

This literature review evaluated the relationship between neuropathic orofacial pain and the nerve injury associated with dental implants replacement, focusing in the clinical, prevention and management aspects. Material and methods: PubMed and SciELO database were analyzed in this literature review. We considered only clinical studies published between 1993 and 2013. Results: we selected and included 18 articles of which, six were case reports, seven were observational studies, um randomized controlled trial and 4 literature reviews. Most of the articles highlighted the transitory nature of the neuronal damage associated with dental implants replacement. Conclusion: the early recognition of signs and symptoms of neuronal damage, as well as the follow-up during the healing period are good clinical practices and should be endorsed in order to avoid chronifi cation...

Humans , Dental Implants , Facial Nerve Injuries , Facial Pain , Mandibular Nerve , Toothache
Article in English | IMSEAR | ID: sea-154559


Paroxysmal hemicrania (PH) is a trigeminal autonomic cephalalgia, a rare primary headache characterized by unilateral periorbital and/or temporal attacks of severe intensity and short duration. In this situation, the determination of a correct diagnosis is crucial for the establishment of a proper management strategy. In the case of head and facial pain, this step is usually a big challenge since many conditions share the same features, as some primary headaches and temporomandibular disorders (TMD). The relationship between PH and TMD has not been determined. This paper describes a case of a female patient diagnosed with TMD and presenting concomitant headache attacks fulfilling the International Headache Society's criteria for PH. It is also emphasized the importance of dentist in this scenario, for many times responsible for the initial diagnosis of facial/head pain. Moreover, it is presented an integrated and simultaneously approach of both conditions, PH and TMD.

Diagnosis, Differential , Facial Pain/diagnosis , Facial Pain/etiology , Female , Headache/diagnosis , Headache/etiology , Humans , Paroxysmal Hemicrania/diagnosis , Paroxysmal Hemicrania/etiology , Temporomandibular Joint Disorders/diagnosis , Temporomandibular Joint Disorders/diagnosis
J. appl. oral sci ; 20(6): 594-602, Nov.-Dec. 2012. ilus
Article in English | LILACS | ID: lil-660628


Temporomandibular disorders (TMD) are characterized by the presence of temporomandibular joint (TMJ) and/or masticatory muscle pain and dysfunction. Low-level laser is presented as an adjuvant therapeutic modality for the treatment of TMD, especially when the presence of inflammatory pain is suspected. Objective: To systematically review studies that investigated the effect of low level laser therapy (LLLT) on the pain levels in individuals with TMD. Material and Methods: The databases Scopus, embase, ebsco and PubMed were reviewed from January/2003 to October/2010 with the following keywords: laser therapy, low-level laser therapy, temporomandibular joint disorders, temporomandibular joint dysfunction syndrome, temporomandibular joint, temporomandibular, facial pain and arthralgia, with the inclusion criteria for intervention studies in humans. exclusion criteria adopted were intervention studies in animals, studies that were not written in english, Spanish or Portuguese, theses, monographs, and abstracts presented in scientific events. Results: After a careful review, 14 studies fit the criteria for inclusion, of which, 12 used a placebo group. As for the protocol for laser application, the energy density used ranged from 0.9 to 105 J/cm², while the power density ranged from 9.8 to 500 mW. The number of sessions varied from 1 to 20 and the frequency of applications ranged from daily for 10 days to 1 time per week for 4 weeks. A reduction in pain levels was reported in 13 studies, with 9 of these occurring only in the experimental group, and 4 studies reporting pain relief for both the experimental group and for the placebo. Conclusion: Most papers showed that LLLT seemed to be effective in reducing pain from TMD. However, the heterogeneity of the standardization regarding the parameters of laser calls for caution in interpretation of these results. Thus, it is necessary to conduct further research in order to obtain a consensus regarding the best application protocol for pain relief in patients with TMD.

Humans , Facial Pain/radiotherapy , Low-Level Light Therapy , Temporomandibular Joint Disorders/radiotherapy , Clinical Protocols , Pain Measurement , Radiation Dosage , Treatment Outcome
Rev. Esc. Enferm. USP ; 46(3): 590-596, jun. 2012. ilus, tab
Article in Portuguese | LILACS, BDENF | ID: lil-640396


Este estudo teve como objetivo identificar a frequência de sintomas ansiosos e depressivos verificando a associação entre a ansiedade-traço, sintomas atuais de depressão e ansiedade nos fibromiálgicos. Foram entrevistados 60 sujeitos com diagnóstico de fibromialgia no Ambulatório de Reumatologia da Universidade Federal de Sergipe, entre agosto de 2007 a março de 2008, sendo aplicados dois questionários: Escala Hospitalar de Ansiedade e Depressão (EHAD) e o Inventário de Ansiedade Traço-Estado (IDATE-T). A frequência de sintomas depressivos e ansiosos foi, respectivamente, de 50% e 86% para os fibromiálgicos e a média do escore do traço ansioso foi de 59,38. Detectou-se associação entre a ansiedade-traço e estado. A ansiedade e a depressão foram sintomas frequentes nos pacientes com fibromialgia. Entretanto, a ansiedade revelou-se um sintoma secundário mais frequente que a depressão, apresentando-se uma forma mais grave, sendo uma comorbidade que deve ser melhor valorizada e estudada.

The objective of this study was to identify the frequency of anxiety and depression symptoms by verifying the association between anxiety traits, current depression and anxiety symptoms in fibromyalgia patients. Interviews were performed with 60 subjects diagnosed with fibromyalgia at the Rheumatology Outpatient Clinic at Universidade Federal de Sergipe between August 2007 and March 2008, in which two questionnaires were administered: the Hospital Anxiety and Depression Scale (HADS) and the State-Trait Anxiety Inventory (STAI). The frequency of anxiety and depression symptoms was, respectively, 50% and 86% for individuals with fibromyalgia, and the mean trait-anxiety score was 59.38. An association was observed between trait and state anxiety. Anxiety and depression were frequent symptoms among patients with fibromyalgia. However, anxiety appeared as a secondary symptom to depression, appearing in a more severe form, and, therefore, this comorbidity should be more valued and studied.

Se objetivó identificar la frecuencia de síntomas de ansiedad y depresión y verificar la asociación entre ansiedad-rasgo y síntomas actuales de depresión y ansiedad en fibromiálgicos. Fueron entrevistados 60 sujetos con diagnóstico de fibromialgia en Ambulatorio de Reumatología de Universidad Federal de Sergipe, de agosto 2007 a marzo 2008. Se aplicaron dos cuestionarios: Escala Hospitalaria de Ansiedad y Depresión (EHAD) e Inventario de Ansiedad Rasgo-Estado (IDATE-T). La frecuencia de síntomas depresivos y ansiosos fue, respectivamente, 50% y 86% para los fibromiálgicos y el promedio de puntaje del rasgo ansioso fue de 59,38. Se observó asociación entre ansiedad-rasgo y estado. La ansiedad y la depresión fueron síntomas frecuentes en pacientes con fibromialgia. Entretanto, la ansiedad fue un síntoma secundario más frecuente que la depresión y se presentó de forma más grave, resultando una comorbilidad que necesita ser más valorizada y estudiada.

Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Young Adult , Anxiety/diagnosis , Anxiety/etiology , Depression/diagnosis , Depression/etiology , Fibromyalgia/complications , Anxiety/epidemiology , Cross-Sectional Studies , Depression/epidemiology
Rev. CEFAC ; 14(1): 114-121, jan.-fev. 2012. ilus, tab
Article in Portuguese | LILACS-Express | LILACS | ID: lil-617179


OBJETIVO: avaliar, por meio da mastigação sequencial de uma "pastilha" artificial de Optosil, o desempenho mastigatório de indivíduos respiradores nasais e orais. MÉTODO: participaram sessenta sujeitos dentados na faixa etária de 14 a 22 anos. Uma "pastilha" de Optosil foi fornecida a cada participante, que executou 20 ciclos mastigatórios, os fragmentos foram colocados numa coluna de sete peneiras, sendo, posteriormente pesados numa balança de precisão. Os dados obtidos foram submetidos à análise descritiva e inferencial (Teste T e ANOVA). RESULTADOS: os grupos respiradores nasais e respiradores orais foram constituídos de 30 jovens cada, com idade média de 17,87 e 17,83 anos respectivamente. Com relação ao gênero houve predominância do gênero feminino no grupo respirador oral e do gênero masculino no grupo respirador nasal Os cinco diagnósticos mais prevalentes no grupo respirador oral foram hipertrofia de adenóide, rinite alérgica, sinusite, asma e hipertrofia de amígdala. Por fim, ao ser realizado o Teste T, não foi encontrada diferença estatística na performance mastigatória nos respiradores orais e nasais (p>0,05). CONCLUSÃO: o padrão respiratório não foi um fator determinante na performance mastigatória.

PURPOSE: the purpose is to evaluate, through the chewing sequence of an Optosil artificial "tablet", the masticatory performance in nasal breathing and mouth breathing. METHOD: we attended sixty dentate subjects aged 14-22 year old. An Optosil "tablet" was supplied to each participant, who executed 20 masticatory cycles, the Optosil fragments had been placed in a column with seven bolters, and the retained particles were weighed on a precision analytical balance and the masticatory efficiency value was calculated. The gotten data were submitted to the descriptive analysis and inferential analysis (test T and ANOVA). RESULTS: the nasal breathing and mouth breathing groups were composed by 30 young people each, with a mean age of 17.87 and 17.83 year old, respectively. Regarding gender, the females predominated in the mouth breathing group and the males in the nasal breathing group. The five most prevalent diagnoses in the mouth breathing group were adenoid hypertrophy, allergic rhinitis, sinusitis, asthma and tonsillar hypertrophy. Finally, when we carried out the t test, there was no statistical difference in masticatory performance in mouth breathing and nasal breathing (p> 0.05). CONCLUSION: it was concluded that the breathing pattern was not a determining factor in the masticatory efficiency.

Braz. dent. j ; 23(3): 252-255, 2012. ilus, tab
Article in English | LILACS | ID: lil-641596


A large number of disorders affecting the masticatory system can cause restriction of mouth opening. The most common conditions related to this problem are those involving the temporomandibular joint (TMJ) and the masticatory muscles, when facial pain also is an usual finding. Congenital or developmental mandibular disorders are also possible causes for mouth opening limitation, although in a very small prevalence. Coronoid process hyperplasia (CPH) is an example of these cases, characterized by an excessive coronoid process growing, where mandibular movements become limited by the impaction of this structure on the posterior portion of the zygomatic bone. This condition is rare, painless, usually bilateral and progressive, affecting mainly men. Diagnosis of CPH is made based on clinical signs of mouth opening limitation together with imaging exams, especially panoramic radiography and computerized tomography (CT). Treatment is exclusively surgical. This paper presents a case of a male patient with bilateral coronoid process hyperplasia, initially diagnosed with bilateral disk displacement without reduction, and successfully treated with intraoral coronoidectomy. It is emphasized the importance of differential diagnosis for a correct diagnosis and, consequently, effective management strategy.

Um grande número de distúrbios pode provocar limitação no grau de abertura bucal. As condições mais comuns relacionadas com esse problema são aquelas que envolvem a articulação temporomandibular (ATM) e músculos mastigatórios, em que, além da limitação, a dor facial é um achado comum. Distúrbios congênitos ou de desenvolvimento da mandíbula também são possíveis causas para limitação de abertura bucal, embora possuam uma baixa prevalência. A hiperplasia do processo coronóide (HPC) é um exemplo dessas causas, caracterizada por um desenvolvimento excessivo do processo coronóide, em que o movimento mandibular torna-se limitado pela impacção dessa mesma estrutura na parte posterior do osso zigomático. Esta condição é rara, indolor, geralmente bilateral e progressiva, afetando principalmente homens. O diagnóstico de HPC é feito por meio dos sinais clínicos de abertura bucal limitada associado com exames de imagem, especialmente a radiografia panorâmica e tomografia computadorizada (TC). O tratamento é exclusivamente cirúrgico. O objetivo desse artigo é apresentar um caso de paciente do sexo masculino com hiperplasia bilateral do processo coronóide, inicialmente diagnosticado com deslocamento de disco sem redução bilateral, e tratado com sucesso com coronoidectomia intraoral. Assim, é enfatizada a importância do diagnóstico diferencial para um correto diagnóstico e, consequentemente, estratégias efetivas de tratamento.

Adolescent , Humans , Male , Mandible/pathology , Temporomandibular Joint , Hyperplasia , Magnetic Resonance Imaging , Mandible , Range of Motion, Articular , Tomography, X-Ray Computed , Temporomandibular Joint/physiopathology , Zygoma
Braz. j. pharm. sci ; 47(4): 861-872, Oct.-Dec. 2011. ilus, graf, tab
Article in English | LILACS | ID: lil-618080


Atranorin (ATR) is the main compound from the lichen Cladina kalbii Ahti, which grows in the arid regions of northeastern Brazil. This study was conducted to evaluate the anti-inflammatory and toxicological properties of ATR. To evaluate anti-inflammatory properties, paw edema was induced by injecting 0.1 mL of carrageenan into the subplantar region of the right hind paw of rats, and leukocyte migration was induced by injection of 500 µL of carrageenan into the peritoneal cavity of mice. In addition, we determined ATR cytotoxicity in L929 cells by MTT assay and acute (5 g/kg-single dose) and subchronic (50 mg/kg-30 days) toxicity tests in Wistar rats. The results showed that ATR (100 mg/kg and 200 mg/kg) exhibited significant anti-inflammatory activity (paw edema and leukocyte migration). In the acute toxicity test, the animals showed hypoactivity and lethargy during the initial period (first 6 hours) and increase in total protein, total and indirect bilirubin, and alkaline phosphatase after 14 days in ATR-treated male rats. The subchronic toxicity test revealed increases in total protein, globulin, gamma-glutamyl transferase, alkaline phosphatase, and total and direct bilirubin in ATR-treated female rats. Histological analysis revealed no changes in the architecture and morphology of the organs. These results suggest that ATR has significant anti-inflammatory activity, with no significant acute and subchronic toxicity or cytotoxicity.

Atranorina (ATR) é o principal composto do líquen Cladina kalbii Ahti, que cresce em terras áridas do nordeste brasileiro. Este estudo foi realizado para avaliar as propriedades antiinflamatórias e toxicológicas da ATR. Para avaliar as propriedades antiinflamatórias, o edema de pata foi induzido, administrando-se 0,1 mL de carragenina na região subplantar da pata traseira direita e a migração leucocitária foi induzida pela injeção de 500 µL de carragenina no peritônio. Além disso, determinou-se a citotoxicidade da ATR, utilizando-se a linhagem celular L929, através do teste de MTT e dos testes de toxicidade aguda (5 g/kg - dose única) e subcrônica (50 mg/kg-30 dias) em ratos Wistar. Os resultados mostraram que nas doses de (100 mg/kg e 200 mg/kg) a ATR exibiu atividade antiinflamatória significativa nos ensaios de edema de pata e migração leucocitária. Nos testes de toxicidade aguda, os animais apresentaram hipoatividade e letargia no período inicial (primeiras 6 horas) e aumento das proteínas totais, bilirrubinas total e indireta e fosfatase alcalina depois de 14 dias nos machos tratados. Para o ensaio subcrônico, houve aumento das proteínas totais, gama-glutamil-transferase, fosfatase alcalina e bilirrubina total e direta nas fêmeas tratadas com ATR. Não foram encontradas alterações na arquitetura e morfologia das lâminas histológicas observadas. Esses resultados sugerem que a ATR apresenta atividade antiinflamatória significativa, sem apresentar significativa toxicidade aguda, subcrônica e citotoxicidade.

Anti-Inflammatory Agents/analysis , Parmeliaceae , Pharmacognosy/classification , Plants, Medicinal