Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 79
Filter
1.
Rev. chil. radiol ; 26(3): 88-99, set. 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1138702

ABSTRACT

Resumen: La pandemia causada por el nuevo coronavirus (SARS-CoV-2) ha derivado en nuevos desafíos en la manera que radiología apoya el trabajo clínico y presta servicios oportunos. El presente artículo revisa las principales publicaciones en la literatura radiológica a la fecha, con énfasis en los sistemas de informe estructurado en tomografía computada y radiografía de tórax. Se relata además nuestra experiencia en las modificaciones realizadas en el Departamento de Radiología para hacer frente a la pandemia.


Abstract: The pandemic caused by the new coronavirus (SARS-CoV-2) has imposed new challenges to the way radiology supports referring clinicians and provides timely services. This article reviews the main radiological publications on COVID-19 to date, with an emphasis on structured reporting schemes in computed tomography and chest radiography. The modifications to clinical practice and academic activities made in our Radiology Department to face the pandemic are also provided.


Subject(s)
Humans , Pneumonia, Viral , Radiography, Thoracic , Tomography, X-Ray Computed , Coronavirus Infections , Pulmonary Embolism , Pandemics , Betacoronavirus
2.
Rev. argent. dermatol ; 101(1): 41-50, mar. 2020. graf
Article in Spanish | LILACS | ID: biblio-1125805

ABSTRACT

Resumen Los Linfomas cutáneos son proliferaciones clonales de Linfocitos T o B neoplásicos. Los linfomas cutáneos B son un grupo heterogéneo de linfomas que se presentan en la piel sin evidencia de compromiso extra cutáneo al momento del diagnóstico y corresponden entre el 20% al 25 % de los linfomas cutáneos primarios.Se presenta un paciente masculino de 71 años, con un linfoma cutáneo de células B centrofolicular localizado en dorso.


Abstract Cutaneous lymphomas are clonal proliferations of neoplastic T or B lymphocytes. Cutaneous B lymphomas are a heterogeneous group of lymphomas presented in the skin without evidence of extra cutaneous harm at the moment of diagnosis and correspond between the 20% and the 25% of primary cutaneous lymphomas. In the current research, a 71 year old masculine patient case is presented, with a cutaneous lymphoma of centrofollicular B cells located at the back.


Subject(s)
Humans , Male , Aged , Immunohistochemistry , B-Lymphocytes/immunology , B-Lymphocytes/pathology , Lymphoma/diagnosis , Diagnosis, Differential , Lymphoma/therapy
3.
Rev. otorrinolaringol. cir. cabeza cuello ; 78(2): 157-160, jun. 2018. tab, ilus
Article in Spanish | LILACS | ID: biblio-961608

ABSTRACT

RESUMEN El síndrome de Churg-Strauss (SCS) es una vasculitis necrotizante sistémica de etiología desconocida, que afecta vasos sanguíneos de pequeño y mediano tamaño. Característicamente se definen tres estadios: prodrómico, hipereosinofílico y una etapa de vasculitis sistémica. Dentro del prodrómico se encuentran manifestaciones del área otorrinolaringológica, que suelen preceder por años a las manifestaciones propias de las vasculitis. Entre ellas destacan la otitis media crónica, rinitis alérgica y rinosinusitis crónica poliposa. Reportamos el caso de un paciente de sexo masculino de 64 años con poliposis nasosinusal bilateral, con biopsia compatible con SCS, encontrándose en estado prodrómico de la enfermedad. Además, presentamos una revisión de la literatura sobre esta patología.


ABSTRACT Churg-Strauss syndrome (CSS) is a necrotizing systemic vasculitis of unknown etiology, which involves small and medium-sized vessels. It is characterized by three stages: prodromic, hypereosinophilic and systemic vasculitis. In the prodromal stage we can find otolaryngological manifestations (including chronic otitis media, allergic rhinitis, chronic rhinosinusitis with polyps) that usually precede the proper manifestations of the vasculitis by years. Here, we report a 64-year old male patient with sinonasal polyps and biopsy compatible with CSS, being in the prodromal stage of the illness. Also, we present a review of this disease.


Subject(s)
Humans , Male , Middle Aged , Churg-Strauss Syndrome/drug therapy , Churg-Strauss Syndrome/diagnostic imaging , Nasal Polyps/complications , Sinusitis/drug therapy , Vasculitis , Tomography, X-Ray Computed , Rhinitis/drug therapy , Diagnosis, Differential
4.
Rev. méd. Chile ; 145(8): 1067-1071, ago. 2017. graf
Article in Spanish | LILACS | ID: biblio-902586

ABSTRACT

Saprochaete capitata (S. capitata) fungal sepsis is a severe condition with a clinical presentation that is similar to other yeast originated fungal sepsis. It is observed in patients with hematological malignancies such as acute myeloid leukemia and neutropenia. We report a 23 year old male presenting with cough, fever and malaise. A bone marrow biopsy led to the diagnosis of acute myeloid leukemia. During the first cycle of chemotherapy the patient presented fever: blood cultures were positive for Klebsiella pneumoniae. Despite antimicrobial treatment, fever persisted; a computed tomography showed a focal splenic lesion; a left exudative pleural effusion appeared. A Matrix Assisted Laser Desorption Ionization-Time of Flight mass spectrometry identified the presence of S. capitata. After multiple antifungal treatments and pleural cavity cleansing by means of videothoracoscopy and laparoscopic splenectomy, the infection resolved and the patient completed his chemotherapy.


Subject(s)
Humans , Male , Young Adult , Leukemia, Myeloid, Acute/microbiology , Fungemia/surgery , Dipodascus/isolation & purification , Pleurisy/microbiology , Pleurisy/pathology , Splenectomy/methods , Splenic Diseases/surgery , Splenic Diseases/microbiology , Splenic Diseases/pathology , Drainage/methods , Treatment Outcome , Fungemia/pathology , Fungemia/drug therapy , Antifungal Agents/therapeutic use
5.
Rev. otorrinolaringol. cir. cabeza cuello ; 77(2): 157-163, jun. 2017. ilus, tab
Article in Spanish | LILACS | ID: biblio-902756

ABSTRACT

El angiomiolipoma de cavidad nasal es un tumor hamartomatoso extremadamente infrecuente compuesto por adipocitos maduros, espacios vasculares con escaso tejido elástico y la presencia de haces de células musculares lisas maduras. Se manifiesta principalmente por obstrucción nasal unilateral y epistaxis recurrente. Se presenta el caso de una paciente de 73 años con historia crónica de obstrucción nasal y epistaxis recurrente izquierda asociada a rinorrea y descarga posterior intermitente. La tomografía computarizada (TC) y resonancia nuclear magnética (RNM) demuestran una lesión vascular circunscrita en fosa nasal izquierda. La angiografía demostró irrigación exclusiva de la arteria esfenopalatina izquierda. Se realizó extirpación de la lesión por abordaje endonasal endoscópico previa embolización arterial. La revisión de la literatura mundial muestra que es el duodécimo caso de angiomiolipoma de cavidad nasal reportado.


Angiomyolipoma of nasal cavity is an extremely rare hamartoma tumor composed of mature adipocytes, vascular spaces with lack of elastic tissue, and the presence of bundles of mature smooth muscle cells. It manifests itself mainly by unilateral nasal obstruction and recurrent epistaxis. We present the case of a 73-years-old woman with chronic history of left-sided nasal obstruction and recurrent epistaxis associated with rhinorrhea and intermittent post nasal drip. Computed tomography and magnetic resonance imaging demonstrate a vascular lesion inside the left nasal cavity. Angiography showed irrigation exclusively by the left sphenopalatine artery Surgical excision was performed by endoscopic endonasal approach after arterial embolization. World literature review showed that this is the twelfth reported case of angiomyolipoma of the nasal cavity.


Subject(s)
Humans , Female , Aged , Nose Neoplasms/surgery , Nose Neoplasms/diagnosis , Angiolipoma/surgery , Angiolipoma/diagnosis , Endoscopy/methods , Magnetic Resonance Imaging , Cerebral Angiography , Tomography, X-Ray Computed , Epistaxis/etiology , Nasal Cavity
6.
Med. U.P.B ; 36(1): 9-15, ene.-jun. 2017.
Article in Spanish | LILACS, COLNAL | ID: biblio-837119

ABSTRACT

Objetivo: evaluar la frecuencia de Experiencias Adversas de la Infancia (EAI) y las características sociodemográficas de la población con enfermedad crónica. Metodología: se condujo un estudio tipo corte transversal descriptivo, en el que se entrevistaron 121 pacientes mayores de 18 años de edad con enfermedades crónicas no transmisibles que acudieron a consulta externa de Medicina Interna en la Fundación Valle del Lili entre septiembre de 2015 y diciembre de 2015. A los participantes les aplicaron escalas validadas para evaluar EAI y otras variables clínicas de interés. Se realizó un análisis descriptivo de los datos. Resultados: de los participantes, el 69.4% estaba conformado por mujeres, la mediana de edad de los participantes fue 62 años con un RIQ de 50 a 72 años. Se encontró que el 64% de los encuestados presentó por lo menos un tipo de EAI, y el 23% presentó cuatro o más EAI y el abuso físico y la separación parental son los más frecuentes (32% y 23%, respectivamente). Conclusiones: las Experiencias Adversas de la Infancia son eventos prevalentes en nuestra población; sin embargo, no se les ha prestado la atención debida. Se necesitan más estudios para medir el impacto real a corto y a largo plazo, con las implicaciones respectivas para nuestro sistema de salud.


Objective: To evaluate the frequency of Adverse Childhood Experiences (ACEs) and the sociodemographic characteristics of the population with chronic disease. Methodology: Cross-sectional descriptive study that was conducted with 121 patients over age 18 with non-communicable, chronic diseases that sought internal medicine outpatient services at Fundación Valle del Lili from September to December of 2015. Validated scales to assess ACEs and other clinical variables of interest were applied to patients. Descriptive analysis of the data was conducted. Results: Of the participants, 69.4% was female; the median age was 62 years, with an IQR of 50 to 72 years. It was found that 64% of those surveyed presented at least one type of ACE, and 23% presented four or more ACEs, while physical abuse and parental separation were the most frequent (32% and 23%, respectively). Conclusions: Adverse Childhood Experiences are prevalent events in our population; however, such events have not received the attention needed. Further studies are warranted to measure the short- and long-term actual impact, with the respective implications for our health system.


Objetivo: avaliar a frequência de Experiências Adversas da Infância (EAI) e as características sócio-demográficas da população com doença crônica. Metodologia: se conduz um estudo tipo corte transversal descritivo, no qual se entrevistaram 121 pacientes maiores de 18 anos de idade com doenças crônicas não transmissíveis que procuraram a consulta externa de Medicina Interna na Fundación Valle del Lili entre setembro de 2015 e dezembro de 2015. Aos participantes lhes aplicaram escalas validadas para avaliar EAI e outras variáveis clínicas de interesse. Se realizou uma análise descritivo dos dados. Resultados: dos participantes, 69.4% estava conformado por mulheres, a idade média dos participantes foi de 62 anos com um RIQ de 50 a 72 anos. Se encontrou que 64% dos entrevistados apresentou pelo menos um tipo de EAI, e 23% apresentou quatro ou mais EAI e o abuso físico e a separação parental são os mais frequentes (32% e 23%, respectivamente). Conclusões: as Experiências Adversas da Infância são eventos prevalentes na nossa população; porém, não se há dado a atenção devida. Se necessitam mais estudos para medir o impacto real a curto e a longo prazo, com as implicações respectivas para nosso sistema de saúde.


Subject(s)
Humans , Mental Health , Public Health , Chronic Disease , Physical Abuse , Noncommunicable Diseases
8.
Rev. otorrinolaringol. cir. cabeza cuello ; 76(3): 295-300, dic. 2016. ilus, tab
Article in Spanish | LILACS | ID: biblio-845629

ABSTRACT

Los tumores neuroectodérmicos primitivos son tumores muy infrecuentes. Derivan de células embrionarias de la cresta neural, y comparten características con los sarcoma de Ewing extraóseos. Se presentan habitualmente en niños y adultos jóvenes, su ubicación más frecuente es en la región toracopulmonar, abdomen y extremidades. Son tumores que presentan una agresividad importante, lo que condiciona un pronóstico sombrío. La ubicación en fosas nasales-cavidades perinasales es anecdótica, existiendo el reporte de tan sólo un caso en la literatura mundial de ubicación en cavidad nasal.


Primitive neuroectodermal tumors are rare malignancies arising from embryonic neural crest cells. They share characteristics with extraosseous Ewing sarcoma. They usually occur in children and young adults and the most common location is the thoracopulmonary region, abdomen and extremities. These tumors have significant aggressiveness, which determines their poor prognosis. The location in nasal fossa-paranasal cavities is anecdotal. Until now only one previous case has been reported in the located in the nasal fossa.


Subject(s)
Humans , Male , Middle Aged , Neuroectodermal Tumors, Primitive/diagnosis , Neuroectodermal Tumors, Primitive/surgery , Nose Neoplasms/diagnosis , Nose Neoplasms/surgery
9.
Rev. mex. ing. bioméd ; 34(1): 97-107, abr. 2013. ilus
Article in Spanish | LILACS-Express | LILACS | ID: lil-740150

ABSTRACT

En la actualidad el desarrollo de prótesis presenta problemas que aún no se han solucionado por completo. A pesar de que se han desarrollado varios estudios enfocados a evaluar el funcionamiento de las prótesis, los trabajos que se presentan en la literatura se realizan con suposiciones de carga, de materiales, e incluso se practican bajo condiciones estáticas. La técnica de correlación de imágenes digitales ha sido útil en diversas aplicaciones, pero ha sido poco explorada en el ambiente de las prótesis. En este trabajo se presenta una técnica capaz de medir la deformación real en sistemas protésicos de pacientes amputados, bajo condiciones de carga y postura reales. Empleando el método de correlación de imágenes digitales es posible evaluar la prótesis del paciente sin necesidad de instrumentarla o modificarla. Además es posible conocer los principales puntos de deformación sin tener que fracturar la pieza. Con esta técnica es posible medir las principales zonas de deformación de un sistema protésico, con la ventaja de que la evaluación se pueden llevar a cabo aplicando cargas y posturas reales de un paciente en un análisis dinámico.


At present, the development of prostheses presents problems that have yet to be completely solved. Despite that various studies have been developed to evaluate the functioning of these prostheses, the works presented in the literature are conducted with suppositions of burden, of materials, and are even practiced under static conditions. The technique of Digital image correlation (DIC) has been useful in diverse applications, but has been scarcely explored in the ambience of prostheses. In this work, we present a technique capable of measuring the real deformation of prosthetic systems in patients with amputations, under real conditions of load and posture. Employing the DIC method, it is possible to evaluate a patient?s prosthesis without the need for instrumenting or modifying it. In addition, it is possible to know the main points of deformation without having to ultimate load the piece. With this technique, it is possible to measure the prosthetic system?s main deformation zones, with the advantage that evaluation can be performed applying the real loads and postures of a patient in a dynamic analysis.

10.
Article in Spanish | LILACS | ID: lil-748676

ABSTRACT

El diseño de la embocadura adecuada, requiere por parte de los músicos muchos años y horas de práctica, desarrollando y manteniendo posturas prolongadas que suponen una sobrecarga para órganos que no están diseñados para el esfuerzo continuado. El presente artículo refleja estudios realizados, donde se recabó información que refleja la relación entre las maloclusiones y el uso de instrumentos viento madera, observando como influye en la maloclusión que padece cada paciente, el instrumento que toca, el número de horas semanales que práctica, la edad del inicio de la ejecución, el tipo de boquilla que posee el instrumento. Se puede resaltar que los resultados de estudios previos arrojaron como resultado que la maloclusión con mayor prevalencia es la Clase I tipo I, seguida por la clase II División 2 . Según los resultados se puede concluir que los instrumentos musicales de viento deben ser tomados en cuenta como factores postnatales ambientales etiológicos de maloclusiones dentarias


The design of the mouth proper, required by musicians for many years and hours of practice, developing and maintaining long positions that can strain bodies are not designed for continuous effort. This article reflects studies where information was collected that reflects the relationship between malocclusions and the use of woodwind instruments, observing how malocclusion affects each patient suffering, the instrument he plays, the number of hours a week practicing, age of onset of implementation, nozzle type which has the instrument. One may notice that the results of previous studies yielded the result that the most prevalent malocclusion is Class I type I, followed by Class II Division 2. According to the results we can conclude that the wind instruments should be taken into account as environmental etiologic postnatal factors of dental malocclusion


Subject(s)
Humans , Male , Female , Malocclusion, Angle Class I , Malocclusion, Angle Class II , Malocclusion, Angle Class III , Music , Dentistry
11.
Rev. Fac. Cienc. Méd. (Córdoba) ; 70(4): 193-200, 2013.
Article in Spanish | LILACS, BINACIS | ID: biblio-1170962

ABSTRACT

OBJECTIVE: To compare the glycemic level patients with type 2 diabetes (T2DM) with and without Metabolic syndrome (MS). METHODOLOGY: cross sectional study. Included patients randomly DM2 corroborated in your clinical record. The SM was identified in patients with at least 3 of 5 criteria of ATP III (Adult Treatment Panel III). A questionnaire was structured. Hemoglobin was determined (HbA1c), HDL-cholesterol, triglycerides, hypertension (HBP), body mass index (BMI), waist circumference (WC) and hip (NCC). RESULTS: 283 patients were included. Mean age was 59.8 ± 10.6. The predominant sex was female (73.6


. The prevalence of MS was 86.6


). There was significant difference in mean HbA1c level in patients with and without MS, HAS, OR, and low HDL. In contrast, subjects with hypertriglyceridemia had an HbA1c level significantly higher than those without hypertriglyceridemia (8.9


2.1, respectively, P = 0.01). HbA1c is positively correlated with triglycerides (r = 0.24, p = 0.001), and negatively with weight (r = -0.19, p = 0.001), BMI (r = -0172, p = 0.004), CCI (r = -0.12, P = 0.004) and CCA (r = -0.14, p = 0.02). In adjusted multivariate analysis, only the duration of diabetes was associated with glycemic level (OR = 1.014, 95


in 1.010 to 1.016). CONCLUSIONS: We not found differences significant glycemic level in patients with and without MS.


Subject(s)
/blood , Blood Glucose/analysis , Metabolic Syndrome/blood , Analysis of Variance , Waist Circumference/physiology , /complications , Cross-Sectional Studies , Sex Factors , Female , Humans , Aged , Male , Mexico , Middle Aged , Prevalence , Metabolic Syndrome/complications
13.
Int. j. morphol ; 30(3): 834-839, Sept. 2012. ilus
Article in English | LILACS | ID: lil-665488

ABSTRACT

The aim of this study was to determine the cytomorphological characteristics of circulating tumor cells (CTCS) in patients with colo-rectal cancer and compare them with the primary tumor and metastasis. CTCS were obtained from blood using differential gel centrifugation and detected using standard immunocytochemistry using anti-CEA. Primary CTCs were defined as those detected before surgery and secondary CTCs those detected after. Surgical specimens of the primary tumor and metastasis were evaluated using standard histological methods with hematoxillin and eosin. CTCs both primary and secondary retained the cytomorphological characteristics of the primary tumor, showing marked intra-patient pleomorphism. There were no differences between primary and secondary CTCs in their cytomorphological features. CTCs from patients with signet ring tumors showed the presence of intracellular mucin deposits. Groups of 3 or more CTCs were only seen in patients with metastasis, whereas duplets of CTcs were seen in patients with metastatic and non-metastatic colo-rectal cancer. This study provides an initial analysis of the cytomorphological features of CTCs, providing a foundation for further investigation into the significance and metastatic potential of CTCs...


El objetivo de este trabajo fue determinar las características cito-morfológicas de las células tumorales circulantes (CTCs) en pacientes con cáncer colo-rectal y compararlas con la cito-morfología del tumor primario y de las metástasis. CTCs fueron obtenidas de la sangre venosa usando centrifugación diferencial y detectadas utilizando inmumocitoquímica estándar con un anticuerpo monoclonal contra el antígeno carcino-embrionico. Las CTCs primarias fueron definidas como aquellas detectadas antes de la cirugía, y las CTCs secundarias aquellas detectadas después de la cirugía. Las piezas quirúrgicas fueron analizadas con métodos histológicos estándares con hematoxilina y eosina. Las CTCs primarias y secundarias se mantengan las mismas características cito-morfológicas que el tumor primario, con una grande variabilidad pleomorfica entre los diferentes pacientes. No hubo diferencias entre CTCs primarias y secundarias en términos de su morfología. Las CTCs detectadas en pacientes con tumores tipo anillo en sello tuvieron la presencia de inclusiones de mucina. CTCs agrupadas en 3 o más células solamente fueron detectadas en pacientes con metástasis, mientras la detección de CTCS en grupos de 2 células fueron detectadas en pacientes con o sin metástasis. Este estudio demuestra un análisis inicial de los hallazgos citomorfológicos de las CTCs en pacientes Chilenos con cáncer colo-rectal, y la base para investigaciones futuras acerca la significancia y potencial metastasica de las CTCs...


Subject(s)
Humans , Neoplastic Cells, Circulating/pathology , Colorectal Neoplasms/pathology , Centrifugation , Chile , Immunohistochemistry
14.
Rev. méd. Chile ; 140(6): 767-770, jun. 2012. ilus
Article in Spanish | LILACS | ID: lil-649848

ABSTRACT

Background: Retroperitoneal schwannoma is an uncommon and usually benign condition. We report a 51-year-old woman presenting with a palpable pelvic tumor. The patient was operated on and during the intervention, two retroperitoneal tumors were found and resected. The postoperative course was favorable. Pathology confirmed the diagnosis of retroperitoneal benign shwannomas. After eight years of follow up, there is no evidence of malignant transformation.


Subject(s)
Female , Humans , Middle Aged , Neurilemmoma , Retroperitoneal Neoplasms , Diagnosis, Differential , Neurilemmoma/diagnosis , Neurilemmoma/surgery , Retroperitoneal Neoplasms/diagnosis , Retroperitoneal Neoplasms/surgery , Tomography, X-Ray Computed
15.
Rev. ANACEM (Impresa) ; 6(1): 9-13, abr. 2012. ilus, tab, graf
Article in Spanish | LILACS | ID: lil-640034

ABSTRACT

INTRODUCCIÓN: El Síndrome de Burnout corresponde a la intensificación de la sintomatología del estrés, debido a una relación constante con personas que sufren. OBJETIVO: Establecer la prevalencia del Síndrome de Burnout entre profesionales de salud del Hospital El Pino y su asociación con variables sociodemográficas y laborales. MATERIAL Y MÉTODO: Estudio descriptivo transversal. Muestra de 99 profesionales de salud del Hospital El Pino, se les aplicó el cuestionario Maslach Burnout Inventory y una encuesta de datos elaborada por los autores, durante Septiembre 2009. Se utilizó estadística descriptiva con comparación de porcentajes por prueba Chi Cuadrado. RESULTADOS: Tasa de respuesta del 70,7 por ciento. La presencia del Síndrome de Burnout en profesionales de salud del Hospital El Pino fue del 51,5 por ciento. No hubo asociación estadística entre Síndrome de Burnout y las variables: sexo, edad, áreas de servicios, horas de trabajo, número de turnos noche y estado civil (p<0,05); sí hubo asociación con las variables número de hijos y profesión (p<0,05). DISCUSIÓN: El Síndrome de Burnout tiene una alta y significativa presencia en los profesionales de salud del Hospital El Pino. Es importante aplicar medidas de cuidado y preventivas para proteger al personal de salud frente al Síndrome de Burnout.


INTRODUCTION: Burnout's Syndrome corresponds to the intensification of the own stress’s symptomatology, due to a constant relation with people that suffers. OBJETIVE: To establish the Burnout's Syndrome’s prevalence in the "Health’s Care Professionals of El Pino Hospital" and his association with sociolabor and demographic variables. MATERIAL AND METHOD: Sample of 99 “Health’s Care Professionals of El Pino Hospital”,there was applied the Maslach Burnout Inventory and information survey, during September 2009. Was did descriptive statistics with comparison of percentages by Chi-square test. RESULTS: Rate of response 70.7 percent. Presence of the Burnout's Syndrome 51.5 percent. There was no statistical association between Burnout's Syndrome and the variables: sex, age, areas of services, working hours, number of shifts in the night and marital status (p<0.05). There was a strong association between "number of children" and "profession" with the Burnout's Syndrome (p<0.05). DISCUSSION: Burnout's Syndrome has a high and significant presence in the “Health’s Care Professionals of El Pino Hospital”. It is important to apply care and preventive measures to protect the Health personnel.


Subject(s)
Humans , Male , Adult , Female , Middle Aged , Burnout, Professional/epidemiology , Health Personnel , Burnout, Professional/psychology , Chi-Square Distribution , Chile , Cross-Sectional Studies , Hospitals , Prevalence , Sex Distribution , Socioeconomic Factors , Surveys and Questionnaires
16.
Rev. chil. cir ; 63(4): 394-398, ago. 2011. tab
Article in Spanish | LILACS | ID: lil-597538

ABSTRACT

Background: Hemorrhagic radiation rectitis occurs in 15 percent of patients subjected to pelvic irradiation. One of the treatment alternatives is the topical application of 4 percent formaldehyde. Aim: To report the results of the use of topical formaldehyde in radiation rectitis. Material and Methods: Twenty patients aged 36 to 80 years (13 women) with hemorrhagic radiation rectitis were prospectively recruited. Fistula or stenosis was discarded endoscopically. Formaldehyde was applied in the operating room or at the outpatient clinic. Results: Fifteen patients required repeated transfusions. The application was performed in the operating room in five patients. Bleeding stopped in three patients with one application, in 12 patients with two applications and in four, with three applications. In one patient, bleeding did not stop after the first application and had a sigmoid perforation; therefore no further application was attempted. One patient had a severe proctitis after the procedure, which subsided with symptomatic treatment after 15 days. Conclusions: Topical formaldehyde application for hemorrhagic rectitis is effective to stop bleeding but has complications in 10 percent of patients.


Introducción: La rectitis actínica hemorrágica es una complicación que se presenta en el 15 por ciento de los pacientes sometidos a radioterapia por una neoplasia pélvica. Existen distintas alternativas para su tratamiento, entre las que se cuenta la aplicación de formalina al 4 por ciento. Presentamos los resultados del tratamiento de esta complicación en una serie prospectiva no aleatoria. Material y Método: Desde marzo de 2004 a mayo de 2007 se reclutaron en forma prospectiva todos los pacientes tratados por una rectitis actínica hemorrágica en nuestro servicio. En todos los pacientes se descartó una estenosis o fístula por endoscopia flexible. Los pacientes fueron sometidos a aplicación de formalina en pabellón o ambulatoria según la evaluación del tratante. Resultados: La serie corresponde a 20 pacientes, 13 mujeres, con un promedio de edad de 61 años (36-80), 15 requerían transfusiones a repetición. La indicación de radioterapia fue por un cáncer cérvico uterino en 9 casos, de próstata en 7 casos y endometrio en 4. El promedio de sesiones necesarias para controlar el sangrado fue de 2 (1-3); en 5 pacientes la aplicación se realizó en pabellón. Tres pacientes mejoraron con una aplicación, 12 pacientes con 2 aplicaciones y 4 con 3 procedimientos. Un paciente continúa sangrado después de un procedimiento, pero presenta una perforación de sigmoides en terreno neoplásico y no se intentó una segunda sesión, por lo que se considera un fracaso del procedimiento. Además un paciente presentó una proctitis intensa que cedió con tratamiento sintomático en 15 días, con lo que la morbilidad del procedimiento alcanza a un 10 por ciento. El éxito acumulado es de un 95 por ciento de los casos, con detención del sangrado, sin necesidad de transfusiones. Conclusión: Estimamos que el tratamiento con formalina al 4 por ciento es un procedimiento seguro para el tratamiento de la rectitis actínica hemorrágica, con buenos resultados en la gran mayoría de los pacientes ...


Subject(s)
Humans , Male , Adult , Female , Middle Aged , Aged, 80 and over , Formaldehyde/therapeutic use , Gastrointestinal Hemorrhage/drug therapy , Proctitis/drug therapy , Radiation Injuries/drug therapy , Administration, Topical , Formaldehyde/administration & dosage , Gastrointestinal Hemorrhage/etiology , Hemostatics/administration & dosage , Prospective Studies , Proctitis/etiology , Radiotherapy/adverse effects , Treatment Outcome , Radiation Injuries/complications
17.
Rev. chil. reumatol ; 27(1): 25-28, 2011. ilus
Article in Spanish | LILACS | ID: lil-609901

ABSTRACT

Introducción: El concepto de Osteopetrosis agrupa un conjunto de enfermedades óseas caracterizadas por aumento de la densidad ósea, debido a una disfunción osteoclástica. Esto determina una insuficiente resorción ósea, provocando un aumento en la densidad ósea, osteoesclerosis generalizada, disminución de la resistencia ósea e incluso supresión de la médula ósea. Presentación del caso: Paciente de sexo masculino, de 20 años de edad, antecedentes de consanguinidad, con diagnóstico de osteopetrosis. Se destacan hidrocefalia, retraso del desarrollo psicomotor, anopsia bilateral, fracturas reiteradas, osteomielitis maxilar bilateral crónica e hipoplasia medular. Consulta frecuentemente por episodios reiterados de diátesis hemorrágica (epistaxis y gingivorragia). Radiografías revelan aumento de la densidad ósea, deformidades y esclerosis ósea difusa. Discusión: Llama la atención la prolongada sobrevivencia de este paciente, mantenido con transfusiones de eritrocitos y plaquetas frente a cada episodio hemorragíparo. Conclusiones: El diagnóstico precoz y tratamiento oportuno evitarán alteraciones irreversibles, optimizando la calidad de vida de los pacientes y sus familias.


Introduction: Osteopetrosis refers to a group of bone diseases characterized by increased bone density due to osteoclast dysfunction. This leads to insufficient bone resorption, leading to increased bone density, generalized osteosclerosis, decreased bone strength and even bone marrow suppression. Case report: Man 20 years old, history of consanguinity, diagnosticated with osteopetrosis. Stands out hydrocephalus, psychomotor developmental delay, bilateral anopsia, repeated fractures, chronic bilateral maxillary osteomyelitis, and bone marrow hypoplasia. Frequently consult by repeated episodes of hemorrhagic diathesis (epistaxis and gingivorrhagia). X-rays revealed increased bone density, bone deformities and diffuse osteosclerosis. Discussion: Calls the attention the prolonged survival of this patient, maintained with red cell and platelets transfusions after each bleeding episode. Conclusions: Early diagnosis and prompt treatment prevent irreversible damage, optimizing quality of life of patients and their families.


Subject(s)
Humans , Male , Adult , Bone Diseases, Developmental/etiology , Osteopetrosis/complications , Osteopetrosis , Osteosclerosis/etiology
18.
Rev. otorrinolaringol. cir. cabeza cuello ; 70(3): 231-236, dic. 2010. ilus
Article in Spanish | LILACS | ID: lil-577248

ABSTRACT

El adenoma pleomorfo es la neoplasia más frecuente de glándulas salivales mayores, pero es poco común en la cavidad nasal. Se presenta el caso clínico de una mujer de 41 años, quien consulta por una masa septal izquierda que determina obstrucción nasal ipsilateral cuyo aspecto clínico e imagenológico sugiere una lesión benigna. Se extirpa la lesión por abordaje transnasal directo, con diagnóstico histopatológico compatible con adenoma pleomorfo del tabique nasal (tumor mixto benigno de tipo salival). Se analiza el caso de adenoma pleomorfo de cavidad nasal y se efectúa una revisión bibliográfica del tema. Su importancia radica en su consideración en el diagnóstico diferencial de neoplasias que se desarrollan en la nariz o cavidades perinasales.


Pleomorphic adenoma is the most frequent major salivary glands neoplasm but it is rare in the nasal cavity. We reporta case of a 41 years old woman who complains of a left septal mass and unilateral nasal obstruction. Her clinical and CT-scan aspects suggest a benign lesion. The lesion is removed by direct transnasal approach. The histopathological diagnosis informed pleomorphic adenoma of the nasal septum (benign mixed tumor of salivary-type). We review the literature of nasal pleomorphic adenoma. This diagnosis should be considered in the differential diagnosis of tumors that develop in the nose or perinasal cavities.


Subject(s)
Humans , Female , Adult , Adenoma, Pleomorphic/surgery , Adenoma, Pleomorphic , Nose Neoplasms/surgery , Nose Neoplasms , Adenoma, Pleomorphic/pathology , Diagnosis, Differential , Nasal Septum , Nose Neoplasms/pathology , Tomography, X-Ray Computed , Treatment Outcome
19.
Rev. méd. Chile ; 138(5): 595-604, mayo 2010. ilus, tab
Article in Spanish | LILACS | ID: lil-553260

ABSTRACT

This article aims to review the most relevant morphological and molecular aspects involved in gallbladder (GB) cancer. In Chile, gallbladder cancer is the main cause of death due to cancer, among women older than 40 years. However, there is almost none information about the morphological changes and the genetic alterations in-volved in the beginning and development of this neoplasia. Two carcinogenic ways have been described. The sequence adenoma-carcinoma is accepted to be less frequent and important. The most important is the sequence where a metaplasia evolves to displasia that progresses to carcinoma in situ and fnally it becomes invasive. This progress requires 10 to 15 years approximately. During this time, a continue progression of injuries have been described. Molecular research studies show genetic anomalies in some genes which are temporary events in preneoplastic injuries of the gallbladder. Some of them even exist before the frst morphological changes, while the expression of tumor suppressor genes like p53, adhesion molecules and oncogenes, among others, can be related to late GB carcinogenesis. The K-ras gene seems to play a role in this neoplasia, mainly in those that present an abnormal biliopancreatic union. The microsatelital instability has been found in a small subset of preneoplastic and neoplastic lesions. The existence of methylation in the promotor gene areas has been related to the cellular proliferation, invasion and metastasis and also in cases of chronic cholecystitis, suggesting that this epigenetic phenomenon represents a crucial early event in GB carcinogenesis.


Subject(s)
Humans , Epigenomics , Gallbladder Neoplasms/genetics , Precancerous Conditions/genetics , Genes, Tumor Suppressor , Gallbladder Neoplasms/pathology , Gallbladder/pathology , Metaplasia , Mutation , Oncogenes/genetics , Precancerous Conditions/pathology
20.
Prensa méd. argent ; 97(2): 111-115, abr. 2010.
Article in Spanish | LILACS | ID: lil-601739

ABSTRACT

The aim of this report was to determine retrospectively the prevalence of hepatitis viruses infection by both HBV and HDV, and to identify the genotype in a population of blood donors. From 42,055 sample of donors, the authors study the hepatitis B virus and hepatitis D virus prevalence and molecular analysis in an Argentinean population. The results obtained are detailed in the article.


Subject(s)
Humans , Blood Chemical Analysis , Blood Donors , Genotype , Hepatitis B virus , Hepatitis Delta Virus , Seroepidemiologic Studies , Serologic Tests , Virology
SELECTION OF CITATIONS
SEARCH DETAIL