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1.
Indian J Pathol Microbiol ; 2007 Jan; 50(1): 6-10
Article in English | IMSEAR | ID: sea-75109

ABSTRACT

Renal dysplasia is one of the major renal developmental anomaly characterized by abnormal structural organization and development of metanephric elements. It is usually detected antenatally or in early childhood. The kidney may be multicystic, aplastic, hypoplastic or duplex. We studied 22 cases of cystic renal dysplasia diagnosed over a period often years to identify the spectrum of morphological changes in dysplastic kidney, with special emphasis on mesenchymal changes. Clinical, radiological and gross morphologicalfeatures were noted. Microscopic features were studied in detail, including the epithelial and mesenchymal changes. Twenty-one of the 22 cases studied were children. One case was a 21-year-old adult, which is a rare age at presentation. Male to female ratio was 1.1:1. One of our patients had contra-lateral ureteric stenosis, a rare anomaly reported with renal dysplasia. Ten patients, all autopsy cases, had multi-system congenital anomalies. As cystic renal dysplasia is not a hereditary disease, it must be differentiated from polycystic kidney disease. Other differential diagnoses are cystic nephroma and cystic partially differentiated nephroblastoma. Histopathological examination is the final diagnostic tool since radiological features alone may not be sufficient to exclude other cystic renal lesions. Cartilage may not be seen in all cases of renal dysplasia. Once diagnosed, other associated anomalies should also be looked for.


Subject(s)
Adolescent , Adult , Child , Child, Preschool , Diagnosis, Differential , Epithelium/pathology , Female , Histocytochemistry , Humans , Infant , Infant, Newborn , Kidney/pathology , Male , Mesoderm/pathology , Multicystic Dysplastic Kidney/complications , Polycystic Kidney Diseases/diagnosis
2.
Braz. dent. j ; Braz. dent. j;16(3): 251-253, set. -dez. 2005. ilus
Article in English | LILACS | ID: lil-419852

ABSTRACT

O tumor odontogênico adenomatóide (TOA) é um tumor incomum de origem odontogênica, caracterizado histologicamente pela formação de estruturas tubulares com depósitos do tipo amilóide. A histogênese do TOA ainda é indeterminada e este tumor é frequentemente considerado mais como uma lesão hamartomatosa do que propriamente um neoplasma. O TOA tem comportamento benigno, sendo suficiente a enucleação cirúrgica conservadora ou curetagem. Neste artigo, é descrito um caso de TOA em paciente de 15 anos do sexo feminino, que exibia um edema no lado esquerdo da mandíbula com reabsorção dental. A histopatologia revelou uma variante folicular intra-óssea do tumor odontogênico adenomatóide. Uma breve revisão da literatura é também apresentada.


Subject(s)
Humans , Female , Adolescent , Tooth Resorption/complications , Adenomatoid Tumor/diagnosis , Adenomatoid Tumor/surgery
3.
Indian J Pathol Microbiol ; 2004 Jul; 47(3): 420-2
Article in English | IMSEAR | ID: sea-75328

ABSTRACT

Insular carcinoma of thyroid (ICT) is a rare tumor, which accounts for 4-6% of thyroid malignancies. ICT arising from follicular cells of thyroid shows a characteristic insular growth pattern characterized by solid nests of tumor cells separated by vessels. A 52-year-old female presented with a huge swelling in midline of the neck with retrosternal extension. The patient was euthyroid. Near total thyroidectomy was done. Grossly, the tumour was involving both the lobes and isthmus of thyroid. Microscopic examination revealed features of insular carcinoma. On immunohistochemistry, tumour cells were positive for thyroglobulin and negative for calcitonin.


Subject(s)
Carcinoma/pathology , Female , Humans , Middle Aged , Thyroid Neoplasms/pathology , Thyroidectomy
4.
Indian J Pathol Microbiol ; 2004 Apr; 47(2): 229-30
Article in English | IMSEAR | ID: sea-74508

ABSTRACT

Leiomyomas are rare tumors of the palate amongst which angiomyomas are the commonest sub-type. Recurrence is rare and prognosis is excellent. Only a few case reports are available in literature. We report a case of angiomyoma of the palate presenting as an encapsulated swelling in the roof of the mouth.


Subject(s)
Adult , Angiomyoma/diagnosis , Humans , Male , Palatal Neoplasms/diagnosis
5.
Indian J Pathol Microbiol ; 2004 Apr; 47(2): 225-6
Article in English | IMSEAR | ID: sea-73877

ABSTRACT

Lymphangioma of the fallopian tube is very rare. Only one such case has been reported. A 30-years-old female with lymphangioma of the left fallopian tube is described here. She presented with fever, vaginal bleeding and foul smelling discharge. A mass was felt in left fornix. On exploratory laparotomy, a left tubo-ovarian mass adherent to the surrounding structures was seen. Clinical diagnosis was septic abortion with adhesions. Left-sided partial tubectomy was performed. Histology of the left tube revealed large dilated channels containing lymph in the submucosa. Lymphocytes were also seen in some channels. Histogenesis of lymphangioma remains uncertain. Presence of adhesions in this case suggests a reactive origin. Histopathology is confirmatory for diagnosis.


Subject(s)
Abortion, Septic/diagnosis , Abscess/diagnosis , Adult , Diagnosis, Differential , Fallopian Tube Neoplasms/diagnosis , Female , Humans , Lymphangioma/diagnosis , Pregnancy , Tissue Adhesions
6.
Indian J Pathol Microbiol ; 2003 Oct; 46(4): 660-1
Article in English | IMSEAR | ID: sea-73697

ABSTRACT

We report a 55-year old female who presented with thyroid swelling for six months. She was clinically asymptomatic with normal thyroid functions. Thyroidectomy revealed the left lobe totally replaced by a well-circumscribed grey white homogenous tumor. Microscopically, the tumor comprised of cells arranged in adenoid pattern along with nests of cohesive intermediate cells, some also forming keratin pearls in a sclerotic and inflammatory background. The thin rim of thyroid at the periphery showed features of lymphocytic thyroiditis. No other associated malignancy was seen on thorough screening. The tumor cells were negative for thyroglobulin and calcitonin. The patient was thus diagnosed with Sclerosing mucoepidermoid carcinoma with eosinophilia, thyroid.


Subject(s)
Carcinoma, Mucoepidermoid/complications , Eosinophilia/complications , Female , Humans , Middle Aged , Thyroid Neoplasms/complications
7.
Indian J Pathol Microbiol ; 2003 Jul; 46(3): 473-4
Article in English | IMSEAR | ID: sea-74381

ABSTRACT

We report a case of congenital benign cervical teratoma in a female child. The unusual asymptomatic nature of the tumour and its relationship with the thyroid is highlighted.


Subject(s)
Branchioma/diagnosis , Child , Diagnosis, Differential , Female , Head and Neck Neoplasms/congenital , Humans , Teratoma/congenital
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