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J Indian Med Assoc ; 2004 Mar; 102(3): 138-9, 142, 150
Article in English | IMSEAR | ID: sea-98578


The present study was undertaken in 50 patients of acute stroke to assess the role of glycaemic status on clinical profile and outcome of stroke. Subjects were divided into two groups: Group 1--Comprising of 25 patients of acute ischaemic stroke; Group 2--Comprising of 25 patients of acute haemorrhagic stroke. Each group was subdivided into euglycaemics, stress hyperglycaemics, newly diagnosed diabetics and known diabetics subgroups (stress hyperglycaemics, newly diagnosed diabetics and known diabetics together were called hyperglycaemics). Hyperglycaemics of both the groups had larger sized stroke. Neurological assessment done at day 1 and day 10 by Gillory's scoring system showed statistically significant improvement (P < 0.01) in all neurological functions in the euglycaemic subgroup in both the groups while in the hyperglycaemic subgroup improvement in higher mental function and motor function was insignificant (P > 0.05). There was statistically significant mortality (P < 0.05) (up to 10th day) with the hyperglycaemic subgroup in both the groups as compared to the euglycaemic subgroup.

Acute Disease , Blood Glucose/analysis , Diabetes Complications , Diabetes Mellitus/blood , Glycated Hemoglobin A/analysis , Humans , Prognosis , Prospective Studies , Risk Factors , Stress, Physiological/blood , Stroke/blood , Tomography, X-Ray Computed
Article in English | IMSEAR | ID: sea-91178


Intestinal transit time (ITT) was measured in 10 normal healthy individuals (Group-I) and 15 cases each of predominant anxiety (Group-IIA) and depression (Group IIB). Dietary habits were similar in all subjects. The ITT was significantly faster in group IIA (24.4 +/- 4.2 hrs. P less than 0.001) and significantly slower in Group IIB (47.5 +/- 3.9 hrs. P less than 0.001) as compared to that of Group I (36.5 +/- 0.97 hrs); but there was no correlation between the ITT and the levels of anxiety and depression. Also, physical complaints related to various systems, in the test group, could not be substantiated on physical examination and investigations. Psychological factors play an important role in GIT motility disorders and therapeutic interventions directed at psychological problem appear to be an important part of management.

Adult , Anxiety/physiopathology , Depression/physiopathology , Female , Gastric Emptying , Humans , Male , Middle Aged