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Autops. Case Rep ; 11: e2020227, 2021. tab, graf
Article in English | LILACS | ID: biblio-1142414


Secretory carcinoma of the breast (SBC) is a rare breast neoplasm. Most of the patients present at an early stage with a relatively indolent clinical course. Lymph node and distant metastasis are also very infrequent. The histomorphological features of the secretory breast carcinoma are quite characteristic. Predominantly three histological patterns, solid, microcystic, and tubular, have been noted with copious amounts of intra and extracellular secretory material. Most commonly, no positivity for estrogen receptor (ER), progesterone receptor (PR) and ERBB2(HER2/neu) is observed in SBCs. As SBC can occasionally be hormone receptor-positive, they should not be categorized in the triple-negative breast carcinoma (TNBC) group in general. A very characteristic genetic translocation t (12;15) has been noted in this rare tumor, resulting in a fusion between ETV6 and NTRK3 proteins. We present a case of a 60-year-old lady who presented with right breast lump of 1-month duration and was managed by lumpectomy and sentinel lymph node dissection. Axillary dissection was not performed because the sentinel lymph node biopsy was negative. Postoperative radiotherapy was given to the right breast with a boost to the tumor bed. No adjuvant chemotherapy was given No recurrence has been noted even after a year of the completion of treatment

Humans , Female , Middle Aged , Breast Neoplasms/pathology , Carcinoma/pathology , Translocation, Genetic , Secretory Component , Sentinel Lymph Node Biopsy
Article | IMSEAR | ID: sea-202001


Background: Family planning services like use of modern contraceptives help the couples to delay pregnancy and avoid the unwanted pregnancies. So, understanding the choice of contraceptives for the underserved couples is a key for provision of family planning services. Objective was to assess the contraceptive use among married women of urban slums using semi-structured questionnaire.Methods: The present observational cross-sectional study was conducted over a period of one month i.e. November 2019 in urban slums of Trikuta Nagar, which is a field practice area of Department of Community Medicine, GMC Jammu. Information was gathered from married females of reproductive age group. 50% of the population was selected randomly by lottery method i.e. 90 females. But at the time of study, only 85 married females could be interviewed.Results: The results show that the maximum females belonged to the 15-25 years age group followed by 26-30 years age group. More than 50% were literate, 42.35% had education upto primary level. More than 50% females were self-employed as they were labourers and rests were home-makers. The duration of marriage of most of the respondent women was 0-5 years and 44.70% of women had three living children. 65.88% women had one year gap between the first two pregnancies.Conclusions: The information, education and communication activities about the advantages of using contraceptives and its side-effects while using these contraceptives need to be increased so as to promote the awareness among females of the urban slums.

Article | IMSEAR | ID: sea-202051


Background: Measles is a highly contagious virus, spread by contact with an infected person through coughing and sneezing. Like measles, rubella can be prevented with a safe, effective and inexpensive vaccine. This can be delivered as a rubella vaccine alone, or combined with measles vaccine (MR) or with measles and mumps vaccines (MMR). The objectives of the study were to analyze the barriers for acceptance of MR vaccination in the field area of New Type Primary Health Centre (NTPHC) Miran Sahib, one of the NTPHC of CHC R. S. Pura, field practice area of Department of Community Medicine, GMC Jammu.Methods: A qualitative study which consisting of interviews of parents of children both vaccinated as well as unvaccinated as well as teachers and principals of children of various government and private schools, Female Multipurpose Health Worker (FMPHW)s, accredited social health activist (ASHA) workers and Anganwadi workers where the campaign was conducted was also interviewed.Results: The major barrier to acceptance of MR vaccination was wrong message conducted through some social media that it results in deaths of some children in various places, and also the messages spread in some religions like in Muslim community that the Vaccine leads to infertility. But the sensitization meetings with the parents, school staff by the health team prior to vaccination played a major role and results in the vaccine coverage of 95%.Conclusions: Before eliminating MR, there are many barriers which are needed to be addressed

Article | IMSEAR | ID: sea-201785


Background: Good hygiene practices are very much needed during menstrual period. Adolescent girls especially in rural areas often lack information about good menstrual hygienic practices. Cultural beliefs about menstruation like food taboos, not going to the religious places also have a negative impact on the adolescent girls in the rural areas. This study was undertaken with an aim to evaluate the knowledge, attitude and practices of adolescent girls regarding menstruation and menstrual hygiene.Methods: This cross- sectional study was conducted among adolescent girls from 8th to 12th class, from 5 schools of zone Budhi; which is a field practice area of department of community medicine, GMC Kathua; by simple random sampling technique. Out of total 323 girls, 300 girls willing to participate in the study (convenience sampling) were included. A semi- structured self- administered questionnaire was used.Results: A total of 300 adolescent girls were enrolled in the study. Majority of adolescent girls had fair to good knowledge and practice scores regarding menstruation, menstrual hygiene and its management but poor attitude scores due to some cultural taboos like restrictions in kitchen, religious places etc.Conclusions: Proper IEC activities need to be performed at school level and Anganwadi level to create awareness among adolescent girls regarding menstrual hygiene management so that they are able to make appropriate choices so that it enable them to lead a healthy life and prevent the girls from reproductive tract infections.