ABSTRACT
Based on Chaihu Biejia Decoction (柴胡鳖甲汤, CBD) created by Professor LIU Duzhou, a newly modified CBD has been formulated. The differentiation and treatment of liver cirrhosis can be divided into three stages, that is, the early stage when liver cirrhosis is about to be, the middle stage when liver cirrhosis is formulated after long accumulations, and the late stage when liver cirrhosis has been transformed. Following the pathogenesis, it is recommended to differentiate the abnormal exuberance of zang-fu (脏腑) organs, qi or blood, deficiency or excess, cold or heat in three stages, and newly modified CBD is taken as the basic formula for further modifications. In early stage of liver cirrhosis, the treatment is mainly to invigorate blood and dissolve stasis, clear dampness and heat, and modifications should be made in accordance with the different causes flexibly. The treatment for the middle stage is to soften hardness and dissipate masses, dissolve stasis and clear heat, while fortifying the spleen and supplementing kidneys is accompanied. In the later stage when the healthy qi declines, and the disease is severe and evil prevails, the treatment is to reinforce healthy qi and supplement deficiency, take mild purgation and dispersion, and medicinals to promote urination, stanch bleeding, direct the turbid downward, or open the orifices can be added in accordance with the syndromes so as to treat the branch.
ABSTRACT
Hepatic osteodystrophy (HO) should be treated by stages based on the differentiation of root deficiency and branch excess. The root cause of HO is the insufficiency of the liver, spleen, and kidney, and the branch onset should be differentiated by stages that in the incubation, the pathogenesis is shaoyang (少阳) constraint and block and cardinal disturbance, while in the attack period, it is turbid toxin, static heat, scorching marrow and withering bones. In treatment, attention should be paid to regulating and tonifying the depletion of the liver, spleen, and kidney to cultivate the foundation. In the incubation period, it is suggested to put focus on unblocking cardinal disturbance of shaoyang liver and gallbladder so as to regulate and harmonize qi and blood. In the attack period, the focus should be on dissolving stasis, removing turbidity, and clearing the source to promote gallbladder function and bone strength. In clinical practice, medication should be modified according to individual symptoms, and the root and the branch, the primary and the secondary should be differentiated to closely follow the pathogenesis and be tailored according to the symptoms. At the same time, reasonable and safe medication should be emphasized to protect liver function.
ABSTRACT
Objective@#To analyze myopia related factors among students in Shanghai, to explore associated risky behaviors associated with mild, moderate, high myopia,so as to provide the evidence for the implementation of home and school combination intervention measures.@*Methods@#Six primary and secondary schools (2 primary schools, 2 middle schools and 2 high schools) were selected from each district of Shanghai. The primary schools began to investigate from the fourth grade. All the students in the selected classes participated in the vision test and questionnaire survey. Chi square test was used for categorical data analysis. The relationship between myopia and related behaviors was analyzed by multivariate Logistic analysis.@*Results@#The prevalence of visual-related risky behaviors such as short outdoor time during the day, lack of sleep, long after-school reading and writing time, poor reading and writing posture, and longtime-using mobile electronic screen was higher in girls than in boys (P<0.05), boys were more likely than girls to use computer for long time and read books/electronic screen in sunlight (P<0.05). The group with 3 hours or more than of reading and writing compared with the less than 2 hours, the OR value of mild myopia model was 1.31(1.20-1.44), moderate myopia model was 1.78(1.62-1.96), severe myopia model was 2.37(2.07-2.71). In the model of moderate and high myopia, reading and writing posture, frequency of eye relax, outdoor activity time and watching TV time were also included.@*Conclusion@#The prevalence of myopia related behaviors among primary and secondary school students is high, and there are significant gender differences among different behaviors. Students reading and writing time should be strictly controlled after school. Intervention strategies and measures should be carried out according to the characteristics of different ages and genders.
ABSTRACT
The present study was designed to confirm the use of GM-CSF, made by the Beijing United Biological Engineering Company, in leucocytopenia after chemotherapy in 12 patients with malignant tumor. In patients with malignant tumor the interval leucocytopenia needed shortened 5 days compared with that in control subjects. At the same time GM-CSF could be resistant to infection significantly, especially in patients with complicated infection, and the antibiotic applying time decreased. In addition, clinical experence had shown that there was no obvious side-effects in general dosage. Thus, these findings indicate that GM-CSF is a kind of essential drug in radical chemotherapy in patients with tumor.
ABSTRACT
After the bilateral phrenic nerves of the dogs were stimulated,the effect of amino-phylline on the function of normal and fatigued diaphragm was observed with the determination of transdiaphragmatic pressure-stmulation frequency curve (Pdi-F).and the analysis of the power spectrum of diaphragmatic electromyogram (DMGdi) at spontaneous breathing.After the administration of 10 and 20 mg/kg of aminophylline ,the PDi pf the normal diaphragm was increased and that of the fatigued diaphragm recovered.The Pdi-F curve of the fatigued diaphragm was shifted to the left,and the central frequency,the medium frequency,and the high/low frequency ratio were markedly increased.It is concluded that aminophylline at the therapeutic dosage can imporve the generation of the strength and enhance the recovery of the fatigued diaphragm.