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1.
Korean Journal of Medicine ; : 379-382, 2019.
Article in English | WPRIM | ID: wpr-759943

ABSTRACT

Birt-Hogg-Dubé syndrome (BHD) is a rare autosomal dominant disorder characterized by the formation of hair follicle tumors, kidney tumors, and pulmonary cysts with recurrent spontaneous pneumothorax. A 44-year-old woman visited Wonkwang University Hospital with mild dyspnea. A chest X-ray on admission revealed pneumothorax in both lung fields. Chest computed tomography (CT) revealed both pneumothorax and multiple, irregularly shaped, variable-sized cysts in both lung fields. Upon physical examination, white dome-shaped papules were observed on the face. Histological examination of the skin lesion confirmed fibrofolliculoma, and genetic studies revealed a folliculin gene mutation. Abdominal CT revealed a 1-cm small solid renal mass at the lower pole of the right kidney. We surgically removed the renal tumor, and a histological diagnosis of oncocytoma was made. Here, we report a case of BHD that demonstrated all three clinical manifestations; this is the first case report of its kind in Korea.


Subject(s)
Adult , Female , Humans , Adenoma, Oxyphilic , Birt-Hogg-Dube Syndrome , Diagnosis , Dyspnea , Estrone , Hair Follicle , Kidney , Kidney Neoplasms , Korea , Lung , Physical Examination , Pneumothorax , Skin , Thorax , Tomography, X-Ray Computed
2.
Korean Journal of Medicine ; : 379-382, 2019.
Article in English | WPRIM | ID: wpr-938581

ABSTRACT

Birt-Hogg-Dubé syndrome (BHD) is a rare autosomal dominant disorder characterized by the formation of hair follicle tumors, kidney tumors, and pulmonary cysts with recurrent spontaneous pneumothorax. A 44-year-old woman visited Wonkwang University Hospital with mild dyspnea. A chest X-ray on admission revealed pneumothorax in both lung fields. Chest computed tomography (CT) revealed both pneumothorax and multiple, irregularly shaped, variable-sized cysts in both lung fields. Upon physical examination, white dome-shaped papules were observed on the face. Histological examination of the skin lesion confirmed fibrofolliculoma, and genetic studies revealed a folliculin gene mutation. Abdominal CT revealed a 1-cm small solid renal mass at the lower pole of the right kidney. We surgically removed the renal tumor, and a histological diagnosis of oncocytoma was made. Here, we report a case of BHD that demonstrated all three clinical manifestations; this is the first case report of its kind in Korea.

3.
The Korean Journal of Internal Medicine ; : 340-346, 2018.
Article in English | WPRIM | ID: wpr-713538

ABSTRACT

BACKGROUND/AIMS: Brain and bone metastases are common in patients with lung cancer. The development of metastasis is associated with poor survival in lung cancer patients. Although tumor morphologic features on radiographs are routinely assessed for differentiation between benign and malignant lung nodules, they are not used to predict metastasis. We assessed morphologic features of pulmonary adenocarcinomas with brain/bone metastasis on computed tomography (CT) to identify related factors for metastasis. METHODS: We performed a retrospective analysis of initial chest CT findings (size, type of contour, percentage of necrosis, enhancement, presence or absence of calcification, and air cavity) from 2009 to 2010 of patients with brain or bone metastasis and compared the findings with those of patients without metastases. RESULTS: In total, 128 patients were included (78 men, 52 women; mean age 69 years; range, 36 to 87). Nineteen patients had brain metastases and 32 had bone metastases. Morphologic features associated with brain metastasis included size ≥ 50 mm (odds ratio [OR], 3.37; 95% confidence interval [CI], 1.24 to 9.17; p = 0.013), necrosis ≥ 30% (OR, 4.51; 95% CI, 1.62 to 12.55; p =0.002), and presence of calcification (OR, 3.97; 95% CI, 1.16 to 13.55; p = 0.035). Morphologic features associated with bone metastasis included necrosis ≥ 30% (OR, 4.639; 95% CI, 1.98 to 10.82; p < 0.001) and T 3 to 4 stage (OR, 2.53; 95% CI, 1.07 to 6.00; p = 0.031). CONCLUSIONS: We found that necrosis ≥ 30% was associated with pulmonary adenocarcinoma with brain and bone metastasis at initial chest CT morphologic feature. To validate these results, further research should be conducted.


Subject(s)
Female , Humans , Male , Adenocarcinoma , Brain , Lung , Lung Neoplasms , Necrosis , Neoplasm Metastasis , Retrospective Studies , Tomography, X-Ray Computed
4.
The Korean Journal of Internal Medicine ; : 805-806, 2016.
Article in English | WPRIM | ID: wpr-76283

ABSTRACT

No abstract available.


Subject(s)
Cryotherapy , Hamartoma
5.
Tuberculosis and Respiratory Diseases ; : 272-275, 2015.
Article in English | WPRIM | ID: wpr-114237

ABSTRACT

Malignant melanoma occurs most frequently on the skin. However, it can also arise in other organs and tissues of the body. Primary pulmonary malignant melanoma is a very rare non-epithelial neoplasm accounting for 0.01% of all primary pulmonary tumors. The treatment of choice is surgical resection of the tumor with an oncologically adequate margin as in lobectomy or pneumonectomy. The prognosis of this condition is rather poor. Based on previous data, its 5-year survival is at least 10%. Here, we report a case of an 82-year-old woman whose primary pulmonary melanoma was detected incidentally.


Subject(s)
Aged, 80 and over , Female , Humans , Lung , Melanoma , Pneumonectomy , Prognosis , Skin
6.
The Korean Journal of Internal Medicine ; : 56-61, 2015.
Article in English | WPRIM | ID: wpr-106134

ABSTRACT

BACKGROUND/AIMS: Pleuropulmonary paragonimiasis produces no specific symptoms or radiologic findings, allowing for the possibility of misdiagnosis. We evaluated the specific clinical and pleural fluid features of pleuropulmonary paragonimiasis masquerading as pleural tuberculosis. METHODS: We retrospectively analyzed the clinical and radiologic characteristics of 20 patients diagnosed with pleuropulmonary paragonimiasis between 2001 and 2011. RESULTS: In total, 17 patients presented with respiratory symptoms, including dyspnea (30%), hemoptysis (20%), cough (20%), and pleuritic chest pain (15%). Chest radiographs revealed intrapulmonary parenchymal lesions, including air-space consolidation (30%), nodular opacities (20%), cystic lesions (15%), ground-glass opacities (10%), and pneumothorax (5%). A pleural f luid examination revealed eosinophilia, low glucose levels, and high lactate dehydrogenase (LDH) levels in 87%, 76%, and 88% of the patients, respectively. These traits helped to distinguish pleuropulmonary paragonimiasis from other pleural diseases such as parapneumonic effusion, malignancy, and pleural tuberculosis. CONCLUSIONS: Pleuropulmonary paragonimiasis is often initially misdiagnosed as other pleural diseases. Therefore, it is important to establish the correct diagnosis. In patients with unexplained pleural effusion living in paragonimiasis-endemic areas, pleural fluid obtained by thoracentesis should be examined to distinguish pleuropulmonary paragonimiasis. When marked eosinophilia, high LDH levels, and low glucose levels are identified in pleural fluid, physicians could consider a diagnosis of pleuropulmonary paragonimiasis.


Subject(s)
Adolescent , Adult , Aged , Animals , Child , Child, Preschool , Female , Humans , Male , Middle Aged , Young Adult , Biomarkers/analysis , Diagnosis, Differential , Enzyme-Linked Immunosorbent Assay , Eosinophilia/diagnosis , Glucose/analysis , L-Lactate Dehydrogenase/analysis , Lung Diseases, Parasitic/diagnosis , Paracentesis , Paragonimiasis/diagnosis , Paragonimus westermani/isolation & purification , Pleural Effusion/diagnosis , Predictive Value of Tests , Retrospective Studies , Tomography, X-Ray Computed , Tuberculosis, Pleural/diagnosis
7.
Cancer Research and Treatment ; : 90-100, 2015.
Article in English | WPRIM | ID: wpr-20372

ABSTRACT

PURPOSE: Non-steroidal anti-inflammatory drugs (NSAIDs) and statins are potential chemopreventive or chemotherapeutic agents. The mechanism underlying the deregulation of survivin by NSAIDs and statins in human non-small cell lung cancer cells has not been elucidated. In this study, we investigated the synergistic interaction of sulindac and simvastatin in lung cancer A549 cells. MATERIALS AND METHODS: Cell viability was measured by an MTT assay, while the expression of apoptotic markers, AKT, and survivin in response to sulindac and simvastatin was examined by Western blotting. DNA fragmentation by apoptosis was analyzed by flow cytometry in A549 cells. Reactive oxygen species (ROS) generation was measured by flow cytometry using H2DCFDA and MitoSOX Red, and the effects of pretreatment with N-acetylcysteine were tested. The effects of AKT on survivin expression in sulindac- and simvastatin-treated cells were assessed. Survivin was knocked down or overexpressed to determine its role in apoptosis induced by sulindac and simvastatin. RESULTS: Sulindac and simvastatin synergistically augmented apoptotic activity and intracellular ROS production in A549 cells. Inhibition of AKT by siRNA or LY294002 inhibited survivin, while AKT overexpression markedly increased survivin expression, even in the presence of sulindac and simvastatin. Moreover, survivin siRNA enhanced sulindac- and simvastatininduced apoptosis. In contrast, survivin upregulation protected against sulindac- and simvastatin-induced apoptosis. CONCLUSION: Combined treatment with sulindac and simvastatin augmented their apoptotic potential in lung cancer cells through AKT signaling-dependent downregulation of survivin. These results indicate that sulindac and simvastatin may be clinically promising therapies for the prevention of lung cancer.


Subject(s)
Humans , Acetylcysteine , Anti-Inflammatory Agents, Non-Steroidal , Apoptosis , Blotting, Western , Carcinoma, Non-Small-Cell Lung , Cell Survival , DNA Fragmentation , Down-Regulation , Flow Cytometry , Hydroxymethylglutaryl-CoA Reductase Inhibitors , Lung Neoplasms , Oncogene Protein v-akt , Reactive Oxygen Species , RNA, Small Interfering , Simvastatin , Sulindac , Up-Regulation
8.
Korean Journal of Medicine ; : 699-703, 2015.
Article in English | WPRIM | ID: wpr-177420

ABSTRACT

We report an unusual case of obstructive pneumonia due to an unknown eosinophilic mucoid impaction of the bronchi (MIB). A 54-year-old woman visited our hospital for investigation of abnormal shadows visible on a chest radiograph. Chest computed tomography and bronchoscopic examination revealed pneumonia due to MIB. Histopathological examination of biopsied mucosal tissue revealed extensive eosinophilic infiltration. With the exclusion of medical diseases that can cause eosinophilia, pneumonia due to eosinophilic mucoid impaction of the bronchi was diagnosed. The cause of the eosinophilia remained unknown. The pneumonia and mucoid impaction resolved after oral steroid therapy.


Subject(s)
Female , Humans , Middle Aged , Bronchi , Eosinophilia , Eosinophils , Mucous Membrane , Pneumonia , Radiography, Thoracic , Thorax
9.
Tuberculosis and Respiratory Diseases ; : 289-291, 2014.
Article in English | WPRIM | ID: wpr-107318

ABSTRACT

Malignant fibrous histiocytoma (MFH), a type of sarcoma, is a malignant neoplasm with uncertain origins that arise from both the soft tissues and the bone. The occurrence of MFH on the chest wall is extremely rare. We hereby report a case of a 72-year-old woman who was incidentally detected with MFH after a traffic accident.


Subject(s)
Aged , Female , Humans , Accidents, Traffic , Hemothorax , Histiocytoma, Malignant Fibrous , Sarcoma , Thoracic Wall
10.
Tuberculosis and Respiratory Diseases ; : 222-225, 2013.
Article in English | WPRIM | ID: wpr-78907

ABSTRACT

Malignant fibrous histiocytoma, a type of sarcoma, is a malignant neoplasm with uncertain origin that arises in both the soft tissues and the bone. The occurrence of primary malignant fibrous histiocytoma of the pleura is extremely rare. We report a case of a 65-year-old Korean man who is being diagnosed with primary malignant fibrous histiocytoma of the pleura.


Subject(s)
Histiocytoma, Malignant Fibrous , Pleura , Sarcoma
11.
Tuberculosis and Respiratory Diseases ; : 59-66, 2013.
Article in English | WPRIM | ID: wpr-77371

ABSTRACT

BACKGROUND: This study was conducted in order to elucidate the effects of docetaxel on the growth of peroxiredoxin 1 (Prx1) knockdown A549 xenograft tumors and further tested the role of Prx1 as a predictor for how a patient would respond to docetaxel treatment. METHODS: Effects of docetaxel on the growth of scrambled- and shPrx1-infected A549 xenograft tumors in nude mice were measured. Moreover, immunohistochemical expression of Prx1 was evaluated in paraffin-embedded tissues from 24 non-small cell lung cancer patients who had received docetaxel-cisplatin regimens as a first-line treatment. RESULTS: Docetaxel treatment in Prx1 knockdown xenograft tumor resulted in reduced tumors growth compared with other groups. Prx1 knockdown increased the production of cleaved caspases-8 and -9 in the control itself compared to scramble tumors. Moreover, docetaxel treatment in Prx1 knockdown tissue led to an increased protein band. Phosphorylated Akt was found in Prx1 scramble tissues. Phosphorylated FOXO1 was detected in the docetaxel treatment group. On the other hand, Prx1 knockdown completely suppressed the Akt-FOXO1 axis. The median progression-free survival (PFS) of patients with low Prx1 expression was 7 months (95% confidence interval [CI], 6.0-7.7), whereas the median progression-free survival of patients with high Prx1 expression was 4 months (95% CI, 4.0-5.0). However, high Prx1 expression was not associated with decreased PFS (p=0.114). CONCLUSION: Our findings suggest that elevated Prx1 provides resistance to docetaxel treatment through suppression of FOXO1-induced apoptosis in A549 xenograft tumors, but may not be related with the predictive significance for response to docetaxel treatment.


Subject(s)
Animals , Humans , Mice , Apoptosis , Axis, Cervical Vertebra , Carcinoma, Non-Small-Cell Lung , Disease-Free Survival , Hand , Lung , Lung Neoplasms , Mice, Nude , Peroxiredoxins , Taxoids , Transplantation, Heterologous
12.
Yonsei Medical Journal ; : 396-402, 2013.
Article in English | WPRIM | ID: wpr-89570

ABSTRACT

PURPOSE: C-reactive protein (CRP) has been implicated in various inflammatory and advanced malignant states. Increased serum CRP (s-CRP) levels have been shown to be associated with independent prognostic factors for survival in patients with advanced lung cancer. However, only few studies have focused on the role of CRP in pleural effusions. This study aimed to evaluate the diagnostic and prognostic value of pleural CRP (p-CRP) in lung cancer patients with malignant pleural effusion (MPE). MATERIALS AND METHODS: Pleural effusion (PE) samples were collected from patients with MPE (68 lung cancers; 12 extrathoracic tumors), and from 68 patients with various benign conditions (31 with pneumonia; 37 with tuberculosis). Concentrations of p- and s-CRP were measured by enzyme-linked immunosorbent assay. CRP level in pleural fluid and its association with survival were examined. RESULTS: p-CRP levels correlated with s-CRP levels (r=0.82, p<0.0001). For the differential diagnosis of MPE and benign PE, the area under the receiver operating characteristic curve was greater for p-CRP (0.86) than for s-CRP (0.77). High p-CRP expression significantly correlated with shorter overall survival (p=0.006). P-CRP was independent prognostic factor significantly associated with overall survival on multivariated analysis (p=0.0001). The relative risk of death for lung cancer patients with high p-CRP levels was 3.909 (95% confidence interval, 2.000-7.639). CONCLUSION: P-CRP is superior to s-CRP in determining pleural fluid etiology. Quantitative measurement of p-CRP might be a useful complementary diagnostic and prognostic test for lung cancer patients with MPE.


Subject(s)
Humans , C-Reactive Protein/metabolism , Enzyme-Linked Immunosorbent Assay , Lung Neoplasms/diagnosis , Multivariate Analysis , Pleural Effusion, Malignant/diagnosis , Predictive Value of Tests , Prognosis , Survival Analysis
13.
Korean Journal of Medicine ; : 97-101, 2011.
Article in Korean | WPRIM | ID: wpr-30876

ABSTRACT

Symptomatic renal metastasis from a primary lung malignancy elsewhere in the body is an uncommon feature in disseminated cancer. We report a case of a 1-cm primary squamous cell carcinoma (SCC) of the lung with renal metastasis initially misdiagnosed as primary renal cell carcinoma in a 65-year-old man who presented with left lower quadrant pain.


Subject(s)
Aged , Humans , Carcinoma, Renal Cell , Carcinoma, Squamous Cell , Lung , Neoplasm Metastasis
14.
The Korean Journal of Critical Care Medicine ; : 241-244, 2010.
Article in Korean | WPRIM | ID: wpr-656640

ABSTRACT

Pseudoaneurysm formation in the pulmonary vasculature is a rare but fatal condition. Several etiologies have been described including trauma, complication after cardiac or other surgeries, tuberculosis, necrotizing pneumonia, congestive heart disease, atherosclerosis, cancer and vasculitis. We report a case of pseudoaneurysm found in a patient being treated with status asthmaticus, who developed complications of pneumonia and brain abscess secondary to sepsis.


Subject(s)
Humans , Aneurysm, False , Atherosclerosis , Brain Abscess , Estrogens, Conjugated (USP) , Heart Diseases , Pneumonia , Sepsis , Status Asthmaticus , Tuberculosis , Vasculitis
15.
Tuberculosis and Respiratory Diseases ; : 298-300, 2010.
Article in Korean | WPRIM | ID: wpr-114967

ABSTRACT

Diaphragmatic paralysis can be demonstrated through diaphragmatic elevation on chest X-ray after thoracic lung surgery or the placement of chest tubing. Additional causes of diaphragmatic paralysis are iatrogenic, mass, atelectasis, etc. For the diagnosis of diaphragmatic paralysis, it required some studies (fluoroscopy, computed tomography [CT], magnetic resonance imaging). Diaphragmatic hernia of the liver is a rare clinical entity, usually found after trauma in adults. Congenital diaphragmatic hernia in neonates requires surgery. Non-traumatic diaphragmatic hernia of the liver in an adult is a rare right-sided diaphragmatic hernia. On developing any symptoms, surgery must be performed. When diaphragmatic hernia is incidentally found in adults without trauma, it is placed under observation for a time period. We diagnosed the diaphragmatic herniation of a right hepatic lobe by 16-slice CT scan without surgery.


Subject(s)
Adult , Humans , Infant, Newborn , Diaphragm , Hernia , Hernia, Diaphragmatic , Liver , Lung , Magnetic Resonance Spectroscopy , Pulmonary Atelectasis , Respiratory Paralysis , Thorax
16.
Journal of Lung Cancer ; : 57-63, 2010.
Article in Korean | WPRIM | ID: wpr-22086

ABSTRACT

PURPOSE: Female lung cancers have different clinical features and therapeutic results as compared to those of male lung cancers. The aim of this study was to analyze the differences of Korean men and women with lung cancer. MATERIALS AND METHODS: We re-analyzed the results of a national survey of lung cancer conducted by the Korean Association for the Study of Lung Cancer in 2005. RESULTS: Of the 8,788 patients, 2,124 (24.2%) were female. The mean age at the diagnosis was 62.5 years for the females and 64.8 years for the males and the difference was significant (p<0.001). An age <50 years was more frequent for the women than for the men (16.2% vs. 7.9%, respectively; p=0.001). The stages between genders were different for the patients with non-small cell carcinoma (NSCLC) (p<0.001), but not for the patients with small cell carcinoma. The overall survival time was longer for woman than that for the man (p<0.001). However, the male patients had longer survival for the smokers with adenocarcinoma and the smokers with squamous cell carcinoma. The never smoker female patients had a better survival time than did the smoking female patients, but the male patient' survival was not influenced by the smoking status. The stage-specific survival rates were better for the women at all stages of NSCLC (p<0.001). The women who received chemotherapy had a longer survival time did the men who received chemotherapy (p<0.001). CONCLUSION: Women with lung cancer were relatively overrepresented among the younger patients and they smoked less intensively, raising the question of gender- specific differences in the carcinogenesis of lung cancer. Over-representation of adenocarcinoma was observed in the women regardless of their smoking status. Women with lung cancer had a better prognosis than men; however, the smoking females showed the worst prognosis. Gender and the smoking status are clearly important factors in the therapeutic approach to lung cancer.


Subject(s)
Female , Humans , Male , Adenocarcinoma , Carcinoma, Small Cell , Carcinoma, Squamous Cell , Korea , Lung , Lung Neoplasms , Prognosis , Republic of Korea , Smoke , Smoking , Survival Rate
17.
Journal of Lung Cancer ; : 106-109, 2010.
Article in English | WPRIM | ID: wpr-22078

ABSTRACT

Tumor lysis syndrome (TLS) is an oncologic emergency that is characterized by numerous metabolic abnormalities, including hyperuricemic nephropathy, hyperphosphatemia, hypocalcemia, hyperkalemia and increased serum creatinine. This syndrome is common for tumors with rapid cell turnover and growth rates, and for bulky tumors with high sensitivity to anti-neoplastic treatments. Hence, TLS is a well-recognized clinical problem in hematologic malignancies. TLS is rarely observed to be induced in solid tumors by chemotherapy. Herein we present the second case of TLS that developed during radiotherapy in a patient with non-small cell lung cancer.


Subject(s)
Humans , Carcinoma, Non-Small-Cell Lung , Creatinine , Emergencies , Hematologic Neoplasms , Hyperkalemia , Hyperphosphatemia , Hypocalcemia , Tumor Lysis Syndrome
18.
Tuberculosis and Respiratory Diseases ; : 148-153, 2009.
Article in Korean | WPRIM | ID: wpr-187538

ABSTRACT

Chemical pneumonitis induced by hydrocarbon aspiration is rare in Korea. Kerosene is a petroleum distillate with low viscosity and high volatility. We report two adult cases of chemical pneumonitis caused by the accidental aspiration of kerosene. They were treated successfully with antibiotics and systemic corticosteroids, and recovered without complications.


Subject(s)
Adult , Humans , Adrenal Cortex Hormones , Anti-Bacterial Agents , Kerosene , Korea , Petroleum , Pneumonia , Viscosity , Volatilization
19.
Tuberculosis and Respiratory Diseases ; : 444-450, 2009.
Article in Korean | WPRIM | ID: wpr-73517

ABSTRACT

BACKGROUND: Biomarkers for cancer have several potential clinical uses, including the following: early cancer detection, monitoring for recurrence prognostication, and risk stratification. However, no biomarker has been shown to have adequate sensitivity and specificity. Many investigators have tried to validate biomarkers for the early detection and recurrence of lung cancer. To evaluate plasma G-CSF as such a biomarker, protein levels were measured and were found to correlate with the clinicopathological features of primary lung tumors. METHODS: Between December 2006 and May 2008, 100 patients with histologically-validated primary lung cancer were enrolled into this study. To serve as controls, 127 healthy volunteers were enrolled into this study. Plasma G-CSF levels were measured in lung cancer patients using the sandwich ELISA system (R & D inc.) prior to treatment. RESULTS: The mean plasma G-CSF levels were 12.2+/-0.3 pg/mL and 46.0+/-3.8 pg/mL (mean+/-SE) in the normal and in the cancer groups, respectively. In addition, plasma G-CSF levels were higher in patients with early lung cancer than in healthy volunteers (p<.001). Plasma G-CSF levels were higher in patients who were under 65 years old or smokers. Within the cancer group, plasma G-CSF levels were higher in patients with non small cell lung cancer than in patients with small cell lung cancer (p<.05). Overall, plasma G-CSF levels were shown to increase dependent upon the type of lung cancer diagnsosed. In the order from highest to lowest, the levels of plasma G-CSF tended to decrease in the following order: large cell carcinoma, squamous cell carcinoma, adenocarcinoma, and bronchioloalveolar carcinoma. Plasma G-CSF levels tended to be higher in patients with advanced TNM stage than in localized TNM stage (I, II

Subject(s)
Humans , Adenocarcinoma , Adenocarcinoma, Bronchiolo-Alveolar , Adrenal Glands , Biomarkers , Carcinoma, Large Cell , Carcinoma, Squamous Cell , Enzyme-Linked Immunosorbent Assay , Granulocyte Colony-Stimulating Factor , Lung , Lung Neoplasms , Neoplasm Metastasis , Plasma , Recurrence , Research Personnel , Small Cell Lung Carcinoma
20.
Cancer Research and Treatment ; : 237-240, 2009.
Article in English | WPRIM | ID: wpr-10552

ABSTRACT

Pseudoaneurysm due to cancer is uncommon generally and is extremely rare in lung cancer. We report two cases of false aneurysms due to lung cancer that spontaneously regressed upon chemotherapy without intervention. Both patients had squamous cell carcinoma of the lung and the diagnosis of a pseudoaneurysm was made using computed tomography. There was no evidence of severe bronchial hemorrhage and the psuedoaneurysms were small and well-encased. Chemotherapy was performed and the pseudoaneurysms resolved.


Subject(s)
Humans , Aneurysm , Aneurysm, False , Carcinoma, Squamous Cell , Hemorrhage , Lung , Lung Neoplasms
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