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Article in Chinese | WPRIM | ID: wpr-470433


Objective To study the laparoscopic uterine artery occlusion effect of assisted myomectomy for ovarian function.Methods 90 cases of existing operation indications ofuterine leiomyoma patients were selected as the research objects and divided into 45 cases of the control group and 45 cases of the study group.The control group received laparoscopic uterine myomectomy,the study group received laparoscopic uterine artery occlusion assisted laparoscopic myomectomy comparison between the two groups,the curative effects of the patients with operation and influence on ovarian function and sexual function.Results In the control group,the operation time (72.03 ± 13.53) min was longer than that of the study group(60.05 ± 10.32) min(t =4.722,P <0.05);control group,amount of bleeding during the operation was (125.43 ± 17.69) mL,more than that of the study group (82.46 ± 13.89) mL (t =12.816,P < 0.05);the two group of exhaust time after operation (t =0.711,P > 0.05) the time of hospitalization and postoperative (t =0.466,P > 0.05) showed no significant differences.The control group after 3 months of follicle stimulating hormone (FSH),estradiol (E2) were (6.08 ± 1.35) U/L,(80.31 ± 5.36) pmol/L,the study group after 3 months of FSH,E2 were (6.85 ± 1.42) U/L,(72.39 ± 5.35) pmol/L,the difference between the two groups was statistically significant(t =2.636,t =7.015,P <0.05);sexual function in patients of the two groups after scores were significantly higher than those before operation,there were no statistically significant differences between the two groups (P > 0.05).Conclusion Laparoscopic uterine artery blocking effects of laparoscopic assisted myomectomy in patients with ovarian function can recover quickly,safely and reliably.

Article in Chinese | WPRIM | ID: wpr-439932


Objective:Primary gastric choriocarcinoma (PGC) is a rare tumor. This study aimed to analyze cases reported in Chi-nese and two cases in our hospital. This study was also conducted to investigate the clinical characteristics and treatment of PGC. Meth-ods:The Chinese Medical Current Contents and China Biology Medicine database was retrieved with the following terms:primary gas-tric choriocarcinoma, stomach choriocarcinoma, and ectopic choriocarcinoma. The clinical data in published literature were retrospec-tively analyzed. Two cases from our hospital were also retrospectively analyzed. Results:A total of 16 patients with PGC (14 case stud-ies and 2 cases from our hospital) were included in this study. The average age of the patients was 57.69 years (ranging from 42 years to 79 years). Among the 16 patients, 4 were females and 12 were males. The main clinical manifestation was abdominal discomfort (12/16). Laboratory and imaging tests were non-specific, but HCG-βin all of the patients increased (11/11). Organ or lymph node metasta-sis was found in 13 patients, including 6 cases in which two or more organs showed metastasis. These organs were primarily the liver, the stomach lymph nodes, the lungs, the brain, and the abdominal cavity. Pathological examination results showed that 12 of the 16 cas-es displayed ulcers with necrosis and hemorrhage. The four remaining cases manifested lesions. Lesions may occur in the stomach less-er curvature (5 cases), stomach sinus (6 cases), cardiac (2 cases), and gastric body (3 cases). The histological components of PGC co-ex-isted with other factors, such as adenocarcinoma (7 cases), adenocarcinoma and squamous (2 cases), adenocarcinoma and a signet ring cell (1 case), or pure choriocarcinoma (6 cases). Surgery combined with chemotherapy was the main treatment. A total of 14 patients un-derwent surgical operations. Among these patients seven underwent chemotherapy after surgery and one underwent chemotherapy. Among the 10 patients who were followed up, 8 died within six months after diagnosis. Conclusion:PGC is a rare stomach cancer with poor prognosis and primarily affects older men. No characteristic clinical manifestations were observed, but HCG-βas a specific serum tumor biomarker increased in all of the affected patients. Histological components co-existed with other stomach cancers. Surgical exci-sion combined with chemotherapy was the preferred treatment in early stages, and systemic chemotherapy was the recommended treat-ment in advanced stages.

Article in Chinese | WPRIM | ID: wpr-434484


Objective To summarize and analyze data of solid pseudopapillary tumor of pancreas (SPTP) in China,and investigate its epidemiology,clinical features,diagnosis and treatment.Methods Retrieval of Chinese Medical Current Contents and China Biology Medicine disc by the key words of solid pseudopapillary tumor of the pancreas,papillary cystic tumor of the pancreas,pancreatic papillary epithelial tumor,cystic solid tumor of pancreas and Frantz tumor were performed,and relevant literatures were included.Results A total of 1180 SPTP patients from 117 articles were involved.There were 1054 women and 126 men and the ratio of male to female was 1:8.37.The average age was 29 years old (range 9 ~83 years).Detailed clinical information was available for 1172 cases,and the main clinical manifestations included abdominal discomfort (n=526,44.88%),medical check-up (n=464,39.59%),abdominal mass (n=131,11.18%).Laboratory and imaging tests were non-specific.The tumors size was 1.3~ 30 cm with a mean value of 7.84 cm.Four handreds and seven (36.8%) cases were located in pancreatic head,96 (8.7%)were in pancreas neck and 587 (53.1%) were in the body and tail of pancreas.Eleven handreds and sixteen patients received treatment,and the resection rate was 99.2% (n =1107).Pathological examination showed that 628(57.0%) cases were benign and 306 (27.8%) were presented as malignant behavior,mainly as infiltrative growth and invasion of the surrounding organs,vessels.Nine handreds and seventy-seven cases were followed up (ranging from 1 month to 13 years),and re-occurrence or metastasis were detected in 42 cases (4.3%) and 24 patients died.Conclusions Solid pseudopapillary tumor of pancreas is a rare pancreatic tumor with low-grade malignant potential,and part of this tumor may present as malignant behavior and it primarily affects young females.No characteristics in clinical manifestations,laboratory and imaging tests are found.Pathological examination can confirm the diagnosis.Surgical resection is the therapy of choice and the prognosis is good.