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Objective@#To evaluate the therapeutic effect of mouse nerve growth factor (mNGF) combined with conventional rehabilitation training on children with cerebral palsy (CP).@*Methods@#According to the inclusion criteria, 60 children with CP(spastic diplegia) who were treated at the Third Affiliated Hospital of Jiamusi University were selected by double-blind method from June to December in 2016.Sixty children with CP were stratified according to age, gender and Gross Motor Function Classification System (GMFCS) (the subjects were classified into 2 age groups: 0-2 years old and 2-4 years old), and then they were randomly divided by draw method: the control group received routine rehabilitation; the experimental group received mNGF additionally.The children with CP in the experimental group were treated with 18 μg mNGF every day for 10 days and then discontinued for 5 days, with 20 injections per month for 1 course, a total of 3 courses.After 3 courses of treatment, the changes in Gesell Development Diagnosis Schedules (GDDS), Peabody Developmental Motor Scales-Gross Motor (PDMS-GM), Peabody Developmental Motor Scales-Fine Motor (PDMS-FM) and Range of Motion (ROM) of the lower extremity were compared between the 2 groups.@*Results@#After 3 months of treatment, the changes of Gesell(gross motor: 57.40±18.13, 44.87±10.95; fine motor: 64.83±18.04, 62.60±17.34; adaptability: 76.07±14.99, 70.57±11.19; language: 74.20±15.07, 71.23±13.38, personal-social interaction: 67.40±14.10, 61.40±12.96), PDMS-GM(94.33±16.03, 81.13±20.15), PDMS-FM scores(91.53±19.73, 91.10±15.84) and ROM[adductors angle: left (69.67±22.2)°, (49.17±21.82)°; right (69.83±21.63)°, (49.67±21.61)°; popliteal angle: left (160.08±30.02)°, (125.50±25.78)°; right (160.17±22.46)°, (126.00±25.31)°; dorsal flexion angle of foot: left (10.17±6.09)°, (4.33±7.28)°; right (9.83±6.23)°, (4.83±7.48)°] in the experimental group and the control group were all significantly higher than those before treatment, and the differences were statistically significant (all P<0.05). After 3 months of treatment, the Gesell gross motor(57.40±18.13) and PDSM-GM scores(94.33±16.03) in the experimental group were significantly higher than those (44.87±10.95, 81.13±20.15, respectively) in the control group, and the differences were statistically significant (all P<0.05).@*Conclusions@#Conventional rehabilitation therapy combined with mNGF has more significant effect on the development and motor function of children with CP than routine rehabilitation training.
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Objective@#To explore the prediction of weight loss to the function 1 month after surgery in head and neck cancer (HNC) patients with surgical treatment.@*Methods@#During August to November 2017, 122 HNC patients from a tertiary hospital in Chengdu were included and investigated by the General Information Questionnaire and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30.@*Results@#1 month after surgery, the function scores of HNC patients ranged from 86.67(73.33, 93.33) to 100.00(100.00, 100.00), and the physical function score was the lowest. Patients with weight loss during hospitalization had lower score in physical, role and social function (P<0.05). According to the results of Logistic regression analysis, age (OR=6.262, P<0.05) and Weight loss during hospitalization (OR=4.363, P<0.05) were risk factors for the physical function of HNC patients 1 month after surgery. For social function 1 month after surgery, weight loss during hospitalization (OR=3.306, P<0.05) was the risk factor.@*Conclusions@#Weight loss during hospitalization in HNC patients with surgical treatment can predict the impairment of function 1 month after surgery. Healthcare providers should pay more attention to perioperative nutritional problems of HNC patients, especially the elder patients, and take effective interventions to control the weight during hospitalization to improve patients′ function and quality of life.
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Objective To explore the prediction of weight loss to the function 1 month after surgery in head and neck cancer (HNC) patients with surgical treatment. Methods During August to November 2017, 122 HNC patients from a tertiary hospital in Chengdu were included and investigated by the General Information Questionnaire and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30. Results 1 month after surgery, the function scores of HNC patients ranged from 86.67(73.33, 93.33) to 100.00(100.00, 100.00), and the physical function score was the lowest. Patients with weight loss during hospitalization had lower score in physical, role and social function ( P<0.05). According to the results of Logistic regression analysis, age ( OR=6.262, P<0.05) and Weight loss during hospitalization ( OR=4.363, P<0.05) were risk factors for the physical function of HNC patients 1 month after surgery. For social function 1 month after surgery, weight loss during hospitalization ( OR=3.306, P<0.05) was the risk factor. Conclusions Weight loss during hospitalization in HNC patients with surgical treatment can predict the impairment of function 1 month after surgery. Healthcare providers should pay more attention to perioperative nutritional problems of HNC patients, especially the elder patients, and take effective interventions to control the weight during hospitalization to improve patients′function and quality of life.
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OBJECTIVE To investigate the correlative between anxiety and coping mode of parents of children with air way foreign bodies. METHODS Self-rating anxiety scale (SAS) and simplified coping style questionnaire (SCSQ) were used to investigate the anxiety level and coping mode among 212 parents of children with airway foreign bodies. RESULTS The SAS scores of parents of children with airway foreign bodies was considerably higher than China normal, there was significant difference between the two (P 0.05). CONCLUSION The parents of children with airway foreign bodies have higher anxiety level than the norm, they often take an positive coping style.
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Objective To observe the effect of treating Diabetic Peripheral Neuropathy with Acupoint Injection. Methods 65 patient with DPN were randomly recruited into a control group and a treatment group after adjusting stage. The control group was treated with acupuncture, while the treatment group was treated with the Safflower inoculation fluid acupuncture point injects. Nerve function parameter (MDNS、 NCV) and clinical symptoms were observed after 3 therapeutic courses. Results Nerve function parameter (MDNS、 NCV) and clinical symptoms in the treatment group were apparently improved after treatment (P<0.05) . Conclusion Acupuncture point injected with Safflower inoculation fluid may improve clinical symptoms and nerve functions of DPN patients.
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This article summarized literatures in the recent ten years on the mechanisms of Ci-xue therapy from such aspects as hemorheology, vascular biology, blood constituents and blood coagulating system.
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Objective: To observe the clinical therapeutic effect of Tang Shen Ning(TSN,a prescription of traditional Chinese medicine)for curing the early stage of diabetic nephropathy(DN).Methods: Adopting random and double-blind controlled trial methods,several indexes were observed in terms of uric micro-amount albumin excretion rate,creatinine clearance,hemorheology and platelet function et al.Results: TSN could significantly reduce urinary albumin,glomerulus's hyper-filtration,improve blood stream transform and inhibit platelet aggregation.Conclusion: TSN could protect renal functions during the early stage of DN.