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1.
Article in Chinese | WPRIM | ID: wpr-802113

ABSTRACT

Infertility with diminished ovarian reserve(DOR) is a major problem in the field of reproductive health and it has attracted great attention worldwidely.Function deficiency of the kidney is one of the fundamental pathogenesis for DOR.Traditional Chinese medicines(TCMs) have a long history with rich experience for the treatment of infertility.Some TCMs are very effective in the treatment of kidney deficiency for infertility with DOR.The integrated TCMs and western medicine,and combination of disease differentiation and syndrome differentiation may help for diagnosis and treatment of infertility with DOR.We adopt the concept of unified treatment for special disease,and the methods and principle of treatment can be used.Therefore,we adopt the TCM concept of kidney-tonifying,blood-nourishing,liver-dispersing and spleen-invigorating.The TCMs kidney-tonifying formulae are added and subtracted.TCMs can regulate the reproductive function via multiple systems for simultaneous conditioning of follicular development and ovulation.At the same time,a hypothesis of " simultaneous conditioning of follicular development and ovulation" was proposed.Two-stage therapy with integrated TCMs and western medicine has been used,mainly for increasing the number of eggs,and improving follicle quality.The goal is to achieve simultaneous conditioning of follicular development and ovulation and ultimately for effective treatment of infertility with DOR.

2.
Article in Chinese | WPRIM | ID: wpr-357151

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the effects of intermittent pneumatic compression (IPC) on coagulation function, deep venous hemodynamics and prevention of deep venous thrombosis (DVT) of lower limbs in patients after rectal cancer resection.</p><p><b>METHODS</b>A total of 120 patients undergoing rectal cancer resection were randomly divided into non-IPC group (control group, n=60) and IPC group (n=60). The control group received routine treatment after resection and the IPC group received IPC based on the routine treatments. Prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB), international normalized ratio (INR) and volume of D-dimer (D-D) were detected before operation and 1-, 3-, 5- and 7-day after operation. Meanwhile, blood flow velocity and caliber of external iliac vein, femoral vein and popliteal vein were examined by color Doppler ultrasound, then the average blood flow velocity and blood flow volume were calculated.</p><p><b>RESULTS</b>Incidence of lower limb DVT was 13.3% (8/60) and 1.7% (1/60) in control group and IPC group respectively with significant difference (P<0.05). The differences in PT, APTT and INR were not significant (P>0.05) at 1-day after operation as compared to the preoperative level, while FIB and D-D both increased (P<0.05), all presented no significant difference among the two groups (P>0.05). PT shortened gradually (P<0.05), APTT and INR did not change significantly (P>0.05), FIB and D-D increased gradually (P<0.05), and no significant differences were found between the two groups at the same time point (all P>0.05). All the above parameters in the control group were significantly lower than those in IPC group (all P<0.05).</p><p><b>CONCLUSIONS</b>IPC can improve hemodynamics indexes of deep veins of lower limb in patients after rectal cancer operation, and prevent the lower limb DVT. IPC is a safe, simple and convenient physical therapy.</p>


Subject(s)
Aged , Female , Femoral Vein , Physiology , Hemodynamics , Physiology , Humans , Intermittent Pneumatic Compression Devices , Lower Extremity , Male , Middle Aged , Postoperative Care , Postoperative Complications , Rectal Neoplasms , General Surgery , Venous Thrombosis
3.
Article in Chinese | WPRIM | ID: wpr-246340

ABSTRACT

A brief history and new developments of acupuncture moxibustion in the former Soviet Union is provided in this paper, as well as in Russia. Science of acupuncture-moxibustion was introduced into Russia after the 10th Century. After the foundation of People's Republic of China, acupuncture-moxibustion therapy has drawn widespread attention in the former Soviet Union and Russia since the 1950s. Notably, acupuncture moxibustion therapy was legalized and popularized in mid 1950s in the Soviet Union, which was gradually accepted as a part of the country's medical system. In the latest 20 years, Federal health departments have paid attention to acupuncture-moxibustion therapy and issued laws and regulations on acupuncture reflexotherapy. The number of books and journals about acupuncture-moxibustion has been increasing; clinical application of acupuncture-moxibustion has been spreading and is welcomed by people. Academic exchanges between China and Russia are more frequent, which promoted the development of science of acupuncture-moxibustion in Russia.


Subject(s)
Acupuncture Therapy , History , History, 20th Century , History, 21st Century , Humans , Moxibustion , History , Russia , USSR
4.
Article in Chinese | WPRIM | ID: wpr-330964

ABSTRACT

This study was designed to investigate the biological and immunological characteristics of a human diffuse large B-cell lymphoma (DLBCL) cell line SUDHL-4, and to establish a mouse model for human DLBCL. SUDHL-4 cells were cultured under different conditions. The morphology and in vitro expression of B-cell and tumor-related markers were detected by microscopy and flow cytometry respectively. To establish the transplanted tumor, the cells were injected subcutaneously into SCID mice. Tumor formation and its histomorphology were analyzed. The results showed that the expression of B cell/tumor-related markers was found on cultured SUDHL-4 cells. A stable mouse model of human DLBCL was successfully established in SCID mice by subcutaneous injection of 10(7) SUDHL-4 cells. Tumor tissue from mice exhibited similar histologic manifestation to those of human DLBCL. It is concluded that the SUDHL-4 cells represent a high consistency in immunological characteristics with human DLBCL. Transplantation of SUDHL-4 cells provides a syngeneic mouse model for the study of human DLBCL.


Subject(s)
Animals , Cell Line, Tumor , Disease Models, Animal , Female , Flow Cytometry , Humans , Lymphoma, Large B-Cell, Diffuse , Pathology , Mice , Mice, SCID , Neoplasms, Experimental
5.
Article in Chinese | WPRIM | ID: wpr-344809

ABSTRACT

<p><b>OBJECTIVE</b>To investigate clinical effects and advantages of Wiltse paraspinal approach to thoracolumbar burst fractures.</p><p><b>METHODS</b>From June 2008 to June 2010, the data of 53 patients with thoracolumbar burst fractures with no obviously nerve injury were retrospectively analyzed, including 43 males and 10 females with an average age of 41 years ( ranged, 19 to 62 years). For segmental distribution, 6 cases were T11, 11 cases were T12, 22 cases were L1 and 14 cases were L2. Among them, 28 cases were treated with Wiltse paraspinal approach, and 25 cases with postmiddle approach. The operation time, blood loss, postoperative drainage,VAS score of back, Cobb angle of injured cord, changes of collapse of vertebral and median sagittal diameter of injured vertebral were observed.</p><p><b>RESULTS</b>Compared with two methods, there were advantages in improving operation time, blood loss, postoperative drainage and VAS score of back, but there were no significant differences in improving Cobb angle of injuried cord, changes of collapse of vertebral and median sagittal diameter of injuried vertebral.</p><p><b>CONCLUSION</b>Wiltse paraspinal approach to thoracolumbar burst fractures can achieve the same reduction with postmiddle approach,and has advantages of minimally invasive, less blood, simple operation and rapid recovery, and worth popularizing.</p>


Subject(s)
Adult , Female , Follow-Up Studies , Humans , Lumbar Vertebrae , Diagnostic Imaging , Wounds and Injuries , General Surgery , Male , Middle Aged , Spinal Fractures , Diagnostic Imaging , General Surgery , Thoracic Vertebrae , Diagnostic Imaging , Wounds and Injuries , General Surgery , Tomography, X-Ray Computed , Treatment Outcome , Young Adult
6.
Article in Chinese | WPRIM | ID: wpr-635053

ABSTRACT

Objective To observe the position and mobility of the tape after tension-free vaginal tape-obturator(TVT-O) surgery using transperineal two and three dimensional ultrasonography in patients with stress urinary incontinence.Methods A total of 32 patients with stress urinary incontinence who had TVT-O surgery and cured were enrolled.Transperineal two and three dimensional ultrasonography were performed after operation 3 months later.Both the position,morphology and mobility of the tape at rest and during Valsalva menuaver were observed.Results The tapes were mainly located in the 1/3 connection of the middle and distal urethra.The length of the urethra and the length of the urethra between the bladder neck and the proximal tape at valsalva menuaver were longer than those at rest.The tapes moved front-down at valsalva manuaver according to the mean distance between the tape and the symphysis pubis.The angles of the tapes were smaller at valsalva manuaver without significant difference.Conclusion It is useful to observe the position,morphology and mobility of the tape using transperineal two and three dimensional ultrasonography.The changes of the position and morphology of the tapes at valsalva menuaver were not significant.But the tapes can strengthen the urine control in the middle of urethra.

7.
National Journal of Andrology ; (12): 900-902, 2008.
Article in Chinese | WPRIM | ID: wpr-309752

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the recovery of sexual function of surgically treated male patients with cervical spondylotic myelopathy.</p><p><b>METHODS</b>A prospective and a mean 16-month postoperative follow-up were conducted for 22 male patients surgically treated for cervical spondylotic myelopathy complicated by sexual dysfunction. Their neurologic scores were obtained by the Japanese Orthopedic Association (JOA) Scoring System, their sexual function assessed by the International Index of Erectile Function (IIEF), and their pre- and post-operative reflexogenic and psychogenic erection analyzed by comparison.</p><p><b>RESULTS</b>Most of the patients experienced an obvious improvement in neurological function after the surgery, with a significantly higher JOA score than pre-operation ( P < 0.01). Compared with the preoperative rates of abnormal reflexogenic and psychogenic erection, 82% (18/22) and 18% (4/22) , the average IIEF score was elevated from preoperatively (9.90 +/- 2. 22) to postoperatively (20.89 +/- 3.89), with a statistically significant difference (P < 0.01).</p><p><b>CONCLUSION</b>Cervical spondylotic myelopathy induces sexual as well as neurological dysfunction, mostly with abnormal psychogenic but normal reflexogenic erection. With neurological recovery, most of the patients may experience an improvement in their sexual function after surgery.</p>


Subject(s)
Adult , Aged , Cervical Vertebrae , Erectile Dysfunction , Follow-Up Studies , Humans , Male , Middle Aged , Recovery of Function , Spinal Cord Diseases , General Surgery
8.
Article in Chinese | WPRIM | ID: wpr-247333

ABSTRACT

<p><b>OBJECTIVE</b>To find out association mapping of loci related to schizophrenia on chromosome 1 with microsatellite markers in DNA pooling samples from schizophrenic cases and normal controls in Shandong peninsula.</p><p><b>METHODS</b>A total of 31 microsatellite markers on chromosome 1 spaced at approximately 10 cM were scanned to two separated DNA pooling samples consisting of 119 schizophrenic cases and 119 normal controls respectively. Statistic analysis was performed by Chi-square test method to compare the difference between the ratio of each allele between the two pooling samples.</p><p><b>RESULTS</b>Significant statistic difference was found at D1S2878 between cases and controls, and P< 0.01 at this loci.</p><p><b>CONCLUSION</b>D1S2878 locus on chromosome 1 associates with schizophrenia in Shandong peninsula. Fine mapping and searching for candidate genes are warranted in this region.</p>


Subject(s)
Adult , Case-Control Studies , China , Chromosome Mapping , Chromosomes, Human, Pair 1 , Genetics , DNA , Genetics , Female , Genomics , Humans , Male , Microsatellite Repeats , Genetics , Schizophrenia , Genetics , Pathology
9.
Acta Physiologica Sinica ; (6): 607-611, 2003.
Article in Chinese | WPRIM | ID: wpr-290919

ABSTRACT

The wide frequency band ECG (WFB-ECG) was recorded in 33 (anesthetized) normal pigeons by the microprocessor ECG system (made in Nanjing University) with a wide-frequency response (0-1000 Hz), a high-speed sweep (up to 1401 mm/s) and a high sensitivity (up to 28 mm/mV). The recording methods for limb leads in the pigeon were the same as those in man, except that the needle electrodes (made by No.5 needles) were subcutaneously inserted in the bases of the wings and in the legs. We studied the features of time domain and power spectrum of pigeons WFB-ECG. It presents P, R, S and T waves, but no Q wave, basically similar to the results from Aves described by Sturkie. But there are still many characters that were not be recorded on the conventional ECG: (1) the main QRS complex is inverted and forms the type of rS or rSr , no Q wave in leads II, III, aVF, and the S-T segment is absent, which is different from that of humans. The T wave is upright in leads II, III, and aVF (except one), in agreement with that of man. But in lead aVR, the main QRS complex is upright and forms the type of Rs, and the T wave is inverted without any exception. There is a large notch on the upstroke of S wave without any exception. The amplitude of the notch is 0.413+/-0.133 mV and the duration is 9.733+/-1.291 ms in lead II. (2) The ratio of duration of P wave to P-R segment is about 0.8, lower than that of humans (1.0-1.6), but higher than that of mice (0.4). (3) The low frequency signals (0-80 Hz) are prominent. The relative power content of high frequency range of QRS in lead II is: 100-1000 Hz: (10.181+/-7.443)%; 80-300 Hz: (15.418+/-10.579)%. (4)The QRS vector loop in the frontal plane lies between -90 degrees and -180 degrees. The electrical axis of QRS complex averages -118 +/-10 (ranges from -96 degrees to -136 degrees). The reason that position of vector loop and the direction of main wave of QRS in the pigeon are different from human s and rodent s is probably that the Purkinje fibers cross the whole ventricular wall and terminate in the subepicardium in Aves including pigeons . After the impulses coming from the sinoatrial node reach the ventricular muscles, the subepicardium is depolarized before the endocardium. However in human s and rodent s, the Purkinje fibres only reach one-forth to one-second of the whole thickness from the endocardium to the epicardium, the subendocardium is depolarized before the subepicardium.


Subject(s)
Animals , Columbidae , Physiology , Electrocardiography , Female , Heart , Physiology , Male
10.
Chinese Journal of Pediatrics ; (12): 180-183, 2003.
Article in Chinese | WPRIM | ID: wpr-280544

ABSTRACT

<p><b>OBJECTIVE</b>To study changes of plasma motilin concentration and it's effect on enteral nutrition in premature infants.</p><p><b>METHODS</b>The plasma motilin concentration of 72 premature infants was measured within 12 hours after birth before enteral feeding and on day 3 and 7 of life by using radioimmunoassay. Sixteen full-term neonates were enrolled as controls.</p><p><b>RESULTS</b>(1) The plasma concentrations of motilin in premature infants before enteral feeding after birth and on day 3 and 7 were 198.65 +/- 58.42 ng/L, 248.83 +/- 56.00 ng/L, and 376.77 +/- 139.46 ng/L, respectively, which were significantly lower than those in the control group (300.33 +/- 67.15 ng/L, 334.26 +/- 83.81 ng/L, 510.64 +/- 179.85 ng/L) (P < 0.001 or < 0.01). There was positive correlation between the concentration and gestational age, age in day and the volume of milk. On day 7 the level of motilin was higher than the pre-enteral feeding level of the full term control group. (2) The plasma motilin concentration in feeding un-tolerated premature infants group was lower than that in the normal group, especially on day 3 of life (P < 0.05). (3) Early enteral feeding could improve the plasma motilin levels, gastrointestinal motility and nutrition tolerance in premature infants.</p><p><b>CONCLUSIONS</b>The gastrointestinal functions of premature infants are adaptable to enteral nutrition. Early enteral feeding (including minimal enteral nutrition and non-nutritive sucking) can promote adaptive rapid growth and development of intestine.</p>


Subject(s)
Enteral Nutrition , Female , Humans , Infant, Low Birth Weight , Blood , Infant, Newborn , Infant, Premature , Blood , Infant, Very Low Birth Weight , Blood , Male , Motilin , Blood , Time Factors
11.
Chinese Journal of Oncology ; (12): 295-297, 2003.
Article in Chinese | WPRIM | ID: wpr-347437

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the value of liver transplantation for late hepatocellular carcinoma.</p><p><b>METHODS</b>Thirty-six patients were treated by liver transplantation from August 2000 to February 2002, of which 15 patients had had advanced hepatocellular carcinoma and thirteen of these 15 patients were evaluated for results.</p><p><b>RESULTS</b>The 1-year survival rate was 86% (6/7). Only one patient died of recurrence within 6 months. The tumor-free survival was 5 to 19 months. Till February 2002, two patients have survived for 10 months and 19 months with recurrence.</p><p><b>CONCLUSION</b>In our country, if the patients can afford liver transplantation, advanced hepatocellular carcinoma without extrahepatic metastasis is still indicated for liver transplantation, since some patients may survive relatively long.</p>


Subject(s)
Adult , Carcinoma, Hepatocellular , Mortality , General Surgery , Female , Humans , Liver Neoplasms , Mortality , General Surgery , Liver Transplantation , Male , Middle Aged , Neoplasm Recurrence, Local
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