ABSTRACT
Objective To study insulin resistance and colorectal cancer (CRC) clinical features, pathological characteristics and hazards. Methods A total of 322 cases of CRC patients and 200 healthy subjects divided into CRC group and control group, BMI, WHR, SBP, DBP, FPG, FINS, HOMA-IR, TC, TG, HDL-C, LDL-C, adiponectin of two groups were compared, and to analyze the risk factors of CRC and insulin resistance and pathological features of CRC. Results CRC group, WHR, SBP, FPG, FINS, HOMA-IR, TG values were significantly higher (P<0.05), HDL-C, adiponectin were significantly lower than the control group (P<0.05). Two BMI, DBP, TC, LDL-C values, the difference were not statistically significant (P> 0.05). Family history, metabolic syndrome, FINS, HOMA-IR were risk factors for CRC(P<0.05). Insulin resistance and TNM stage(P<0.05), and not related to tumor location, differentiation, lymph node metastasis, distant metastasis (P>0.05). Conclusion Insulin resistance, family history, prevalence of metabolic syndrome and colorectal cancer is closely related to the degree of insulin resistance may be associated with the progression of colorectal cancer.
ABSTRACT
Objective: To observe the therapeutic action of earth enteral nutrition after jejunum interposition in patients with carcinoma of gastric cardia.Methods: Sixty-two patients after jejunum interposition were divided into early enteral nutrition group(n=33) and parenteral alimentation group(n=29).The clinical observation index and nutrition index were compared between the two groups.Results: The enteral nutrition group had more advantages than the parenteral alimentation group in the aspects of clinical observation index postoperative complication and nutrition index.Conclusion: Early enteral nutrition could improve gastrointestinal function and nutritional state and decrease the incidence rate of postoperative complication.