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Chinese Journal of Hepatology ; (12): 881-883, 2011.
Article in Chinese | WPRIM | ID: wpr-239264


<p><b>OBJECTIVE</b>To study the best time of taking liver biopsy for chronic HBV carriers of age ranges and then guiding antiretroviral treatment.</p><p><b>METHOD</b>The liver biopsy pathologic results of 292 cases of chronic HBV carriers were collected from the First Affiliated Hospital of Kunming Medical College. The patients were divided into three groups according to ages. The differences between groups were compared by calculating the ratio of inflammation above G2 or fibrosis staging above S2.</p><p><b>RESULT</b>The percentages of the chronic HBV carriers with liver histopathology inflammation graded above G2 or fibrosis staging above S2 were 26.5% (36/136) in 11 to 29 year-old group, 39.4% (37/94) in 30-39 year-old group and 58.1% (36/62) in 40-60 year-old group. Significant difference existed among groups in general (P less than 0.01). 39.4% (37/94) of chronic HBV carriers were found with inflammation graded above G2 or fibrosis staging above S2 in 30-39 year-old group, no statistically significant difference found between group 30-39 years old and group and 40-60 years old 58.1% (36/62) (P less than 0.01). 26.5% (36/136) of chronic HBV carriers under 30 years old were with inflammation graded above G2 or fibrosis staging above S2 as compared with the percentage of 46.8% (73/156) in the chronic HBV carriers over 30 years old group, and significant difference existed between the two groups (P less than 0.01).</p><p><b>CONCLUSION</b>The best time choice of taking liver biopsy should be at the ages elder than or equal to 30.</p>

Adolescent , Adult , Age Distribution , Biopsy , Child , Female , Hepatitis B, Chronic , Pathology , Humans , Liver , Pathology , Male , Middle Aged , Young Adult
Microbiology ; (12)1992.
Article in Chinese | WPRIM | ID: wpr-684988


The spores suspension of Streptomyces roseosporus D-38 irritated with 20mW He-Ne laser for 20 min were incubated on G1 medium plates containing 1. 9?g/mL of streptomycin. Ten percent of mutants increased the potency of daptomycin by streptomycin-resistance method, including the mutant LC-54, which could produce daptomycin 81. 2 mg/L, which was 39% higher than that of the beginning strain by flask fermentation.