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1.
Journal of Veterinary Science ; : e60-2023.
Article in English | WPRIM | ID: wpr-1001919

ABSTRACT

Background@#Accurate diagnosis of diseases in animals is crucial for their treatment, and imaging evaluations such as radiographs, computed tomography (CT), and magnetic resonance imaging (MRI) are important tools for this purpose. However, a cross-sectional anatomical atlas of normal skeletal and internal organs of long-tailed gorals (Naemorhedus caudatus) has not yet been prepared for diagnosing their diseases. @*Objectives@#The objective of this study was to create an anatomical atlas of gorals using CT and MRI, which are imaging techniques that have not been extensively studied in this type of wild animal in Korea. @*Methods@#The researchers used CT and MRI to create an anatomical atlas of gorals, and selected 37 cross-sections from the head, thoracic, lumbar, and sacrum parts of gorals to produce an average cross-sectional anatomy atlas. @*Results@#This study successfully created an anatomical atlas of gorals using CT and MRI. @*Conclusions@#The atlas provides valuable information for the diagnosis of diseases in gorals, which can improve their treatment and welfare. The study highlights the importance of developing cross-sectional anatomical atlases of gorals to diagnose and treat their diseases effectively.

2.
Journal of Veterinary Science ; : e45-2022.
Article in English | WPRIM | ID: wpr-926482

ABSTRACT

We describe a case of gastrocnemius muscle rupture in a goral that got caught in a live trap set up to capture wild boars. We established a diagnostic method based on clinical signs and imaging examination findings, including magnetic resonance imaging for gastrocnemius muscle rupture with symptoms such as hindlimb lameness and plantigrade posture of unknown cause in wild animals. Although this condition is rare, this report will help veterinarians diagnose several diseases of the musculoskeletal and nervous systems in wild animals. This is the first report of successful diagnosis and treatment of gastrocnemius muscle rupture in gorals in Korea.

3.
Korean Journal of Veterinary Research ; : e13-2021.
Article in English | WPRIM | ID: wpr-902556

ABSTRACT

Mammalian reovirus (MRV) causes respiratory and intestinal disease in mammals. Although MRV isolates have been reported to circulate in several animals, there are no reports on Korean MRV isolates from wildlife. We investigated the biological and molecular characteristics of Korean MRV isolates based on the nucleotide sequence of the segment 1 gene. In total, 144 swabs from wild animals were prepared for virus isolation. Based on virus isolation with specific cytopathic effects, indirect fluorescence assays, electron microscopy, and reverse transcription-polymerase chain reaction, one isolate was confirmed to be MRV. The isolate exhibited a hemagglutination activity level of 16 units with pig erythrocytes and had a maximum viral titer of 105.7 50% tissue culture infectious dose (TCID50)/mL in Vero cells at 5 days after inoculation. The nucleotide and amino-acid sequences of the partial segment S1 of the MReo2045 isolate were determined and compared with those of other MRV strains. The MReo2045 isolate had nucleotide sequences similar to MRV-3 and was most similar (96.1%) to the T3/Bat/Germany/342/08 strain, which was isolated in Germany in 2008. The MReo2045 isolate will be useful as an antigen for sero-epidemiological studies and developing diagnostic tools.

4.
Journal of Veterinary Science ; : e52-2021.
Article in English | WPRIM | ID: wpr-901430

ABSTRACT

Background@#The normal vertebral anatomy of Korean raccoon dogs and their variants require research attention as a prerequisite for identifying pathologies and anomalies. @*Objectives@#This retrospective study aimed at describing the vertebral formula and congenital vertebral anomalies in Korean raccoon dogs (Nyctereutes procyonoides koreensis). @*Methods@#Radiographs of 82 raccoon dogs (42 males, 40 females) acquired from May 2013 to June 2020 in the Gangwon Wildlife Medical Rescue Center were reviewed to evaluate the cervical, thoracic, and lumbar vertebrae of the spine. @*Results@#Normal morphology of all vertebrae was observed in 50 of the 82 raccoon dogs, and the vertebral formula was cervical 7, thoracic 13, and lumbar 7. Congenital vertebral anomalies were found in 32 raccoon dogs: transitional vertebrae (TV) in 31 and block vertebrae in 2. Two raccoon dogs had 2 types of vertebral anomalies: one had TV and block vertebra, and the other had 2 types of TV. Twenty-nine raccoon dogs had thoracolumbar TV (TTV) and 3 had lumbosacral TV. TTV was morphologically classified into 4 different types:unilateral extra-rib in 5 raccoon dogs, bilateral extra-ribs in 14, bilateral elongated transverse processes in 4, and an asymmetric mixed formation of extra-rib with elongated transverse process in 6. @*Conclusions@#This study showed that TTV is common in Korean raccoon dogs, and that the vertebral formula is relatively diverse. The bilateral extra-ribs type TTV is the most common variant, which is almost similar to normal rib to be confused the radiographic evaluation.

5.
Korean Journal of Veterinary Research ; : e13-2021.
Article in English | WPRIM | ID: wpr-894852

ABSTRACT

Mammalian reovirus (MRV) causes respiratory and intestinal disease in mammals. Although MRV isolates have been reported to circulate in several animals, there are no reports on Korean MRV isolates from wildlife. We investigated the biological and molecular characteristics of Korean MRV isolates based on the nucleotide sequence of the segment 1 gene. In total, 144 swabs from wild animals were prepared for virus isolation. Based on virus isolation with specific cytopathic effects, indirect fluorescence assays, electron microscopy, and reverse transcription-polymerase chain reaction, one isolate was confirmed to be MRV. The isolate exhibited a hemagglutination activity level of 16 units with pig erythrocytes and had a maximum viral titer of 105.7 50% tissue culture infectious dose (TCID50)/mL in Vero cells at 5 days after inoculation. The nucleotide and amino-acid sequences of the partial segment S1 of the MReo2045 isolate were determined and compared with those of other MRV strains. The MReo2045 isolate had nucleotide sequences similar to MRV-3 and was most similar (96.1%) to the T3/Bat/Germany/342/08 strain, which was isolated in Germany in 2008. The MReo2045 isolate will be useful as an antigen for sero-epidemiological studies and developing diagnostic tools.

6.
Journal of Veterinary Science ; : e52-2021.
Article in English | WPRIM | ID: wpr-893726

ABSTRACT

Background@#The normal vertebral anatomy of Korean raccoon dogs and their variants require research attention as a prerequisite for identifying pathologies and anomalies. @*Objectives@#This retrospective study aimed at describing the vertebral formula and congenital vertebral anomalies in Korean raccoon dogs (Nyctereutes procyonoides koreensis). @*Methods@#Radiographs of 82 raccoon dogs (42 males, 40 females) acquired from May 2013 to June 2020 in the Gangwon Wildlife Medical Rescue Center were reviewed to evaluate the cervical, thoracic, and lumbar vertebrae of the spine. @*Results@#Normal morphology of all vertebrae was observed in 50 of the 82 raccoon dogs, and the vertebral formula was cervical 7, thoracic 13, and lumbar 7. Congenital vertebral anomalies were found in 32 raccoon dogs: transitional vertebrae (TV) in 31 and block vertebrae in 2. Two raccoon dogs had 2 types of vertebral anomalies: one had TV and block vertebra, and the other had 2 types of TV. Twenty-nine raccoon dogs had thoracolumbar TV (TTV) and 3 had lumbosacral TV. TTV was morphologically classified into 4 different types:unilateral extra-rib in 5 raccoon dogs, bilateral extra-ribs in 14, bilateral elongated transverse processes in 4, and an asymmetric mixed formation of extra-rib with elongated transverse process in 6. @*Conclusions@#This study showed that TTV is common in Korean raccoon dogs, and that the vertebral formula is relatively diverse. The bilateral extra-ribs type TTV is the most common variant, which is almost similar to normal rib to be confused the radiographic evaluation.

7.
The Korean Journal of Parasitology ; : 55-59, 2021.
Article in English | WPRIM | ID: wpr-875527

ABSTRACT

We intended to describe a case of cerebral coenurosis in a long-tailed goral, Naemorhedus caudatus, from Hwacheon-gun, Gangwon-do (Province), in the Korea. The goral, a 10-year-old male, was suffering from neurological symptoms, such as turning the circle to one side without lifting the head straight, and died at 30 days after admission to the wildlife medical rescue center in Chuncheon-si, Gangwon-do. A fluid-filled cyst was detected in the left cerebral hemisphere by computed tomography and magnetic resonance imaging. The cyst removed from the deceased goral was transparent, about 3×3 cm in size, contained a clear fluid and approximately 320 protoscolices invaginating from the internal germinal layer. The protoscolex had 4 suckers and a rostellum with 28 hooklets arranged in 2 rows. By the present study, a case of cerebral coenurosis was first confirmed in a long-tailed goral, N. caudatus, from Gangwon-do, in Korea. The residents frequently exposed in the sylvatic environment should be careful the accidental infections of zoonotic metacestode of Taenia multiceps, Coenurus cerebralis, in Korea.

8.
Clinical and Experimental Vaccine Research ; : 132-135, 2019.
Article in English | WPRIM | ID: wpr-763367

ABSTRACT

Since 2000, large amounts of rabies bait vaccine have been distributed in two provinces where raccoon dog-mediated rabies has occurred. A total of 146 raccoon dogs were caught in Gangwon and Gyeonggi Provinces from January 2017 to June 2018, and raccoon dog blood samples were collected. Of the 146 raccoon dogs, 13.7% (20/146) had rabies antibodies. In Gyeonggi and Gangwon provinces, the rate of rabies antibody was 8.5% (5/59) and 17.2% (15/87), respectively. Considering these results, it would be desirable to improve the distribution method or use a new bait vaccine to prevent animal rabies in South Korea.


Subject(s)
Animals , Antibodies , Korea , Methods , Rabies , Raccoon Dogs , Raccoons
9.
Korean Journal of Veterinary Research ; : 209-214, 2017.
Article in English | WPRIM | ID: wpr-60683

ABSTRACT

Wild raccoon dogs (Nyctereutes procyonoides koreensis) may play a role transmitting several pathogens to humans and pet animals. Information concerning the incidence of rabies, canine distemper virus (CDV), canine parvovirus (CPV), canine adenovirus type 2 (CAdV-2), canine parainfluenza virus type 5 (CPIV-5), and canine herpesvirus (CHV) is needed in wild raccoon dogs. In total, 62 brain samples of raccoon dogs were examined for rabies virus (RABV) and CDV, and 49 lung samples were screened for CDV, CAdV-2, CPIV-5, and CHV. No RABV, CAdV-2, CPIV-5, or CHV was identified, but nine CDV antigens (8.1%, 9/111) were detected. Moreover, 174 serum samples from wild raccoon dogs were screened for antibodies against the five major viral pathogens. The overall serosurveillance against CDV, CPV, CAdV-2, CPIV-5, and CHV in wild raccoon dogs was 60.3%, 52.9%, 59.8%, 23.6%, and 10.3%, respectively. Comparisons of the sero-surveillance of the five pathogens showed that raccoon dogs of Gyeonggi province have slightly higher sero-positive rates against CDV, CPV, and CHV than those of Gangwon province. These results indicate high incidences of CDV, CPV, and CAdV-2 in wild raccoon dogs of two Korean provinces and a latent risk of pathogen transmission to companion and domestic animals.


Subject(s)
Animals , Humans , Adenoviruses, Canine , Animals, Domestic , Antibodies , Brain , Disease Transmission, Infectious , Distemper , Distemper Virus, Canine , Friends , Incidence , Lung , Paramyxoviridae Infections , Parvovirus, Canine , Rabies , Rabies virus , Raccoon Dogs , Raccoons
10.
Journal of Veterinary Science ; : 587-589, 2016.
Article in English | WPRIM | ID: wpr-167757

ABSTRACT

West Nile virus (WNV) is a mosquito-borne zoonotic pathogen that has spread throughout Europe and the United States. Recently, WNV spread to East and Southeast Asia, and great efforts have been made in South Korea to prevent the spread of WNV from neighboring countries. In this study, we diagnosed the first case of WNV in pigeons (Columba livia domestica) residing in cities using a competitive enzyme-linked immunosorbent assay and confirmed it with nested reverse transcription polymerase chain reaction analysis and sequencing. This is the first report to provide convincing evidence that WNV is present within South Korea.


Subject(s)
Asia, Southeastern , Columbidae , Enzyme-Linked Immunosorbent Assay , Europe , Korea , Polymerase Chain Reaction , Reverse Transcription , United States , West Nile virus
11.
Korean Journal of Veterinary Research ; : 147-153, 2016.
Article in English | WPRIM | ID: wpr-94485

ABSTRACT

A total of 782 blood and 465 tissue samples from 1,039 wild animals and 127 dairy goats were collected from January 2011 to December 2013 in 10 provinces of South Korea and tested for the presence of brucellosis. The Rose Bengal test revealed that 8.0% (52/650) of the serum samples were seropositive, while 4.2% (33/782) of the serum samples were positive for Brucella antibodies by competitive enzyme-linked immunosorbent assay. Of the 650 sera examined, only 16 (2.5%) were positive by both serological tests. Direct polymerase chain reaction (PCR) assay using B4/B5 primers for Brucella abortus (BCSP31) revealed the prevalence of Brucella to be 26.5% (129/487) in blood samples and 21% (98/465) in tissue samples while, 16S rRNA PCR detected Brucella DNA in 6.8% (33/487) and 2.6% (12/465) in blood and tissue samples, respectively. Of PCR-positive samples, only 6.2% (30/487) of blood samples and 2.4% (11/465) of tissue samples were found to be positive by both BCSP31 and 16S rRNA PCRs. However, Brucella strains were isolated by blood culture from only two out of 487 blood samples (0.4%). This characterization and identification of pathogenic Brucella isolates is the first to clearly indicate that the organisms were Brucella abortus biovar 1.


Subject(s)
Animals , Animals, Wild , Antibodies , Brucella abortus , Brucella , Brucellosis , DNA , Enzyme-Linked Immunosorbent Assay , Goats , Korea , Polymerase Chain Reaction , Prevalence , Rose Bengal , Serologic Tests
12.
The Ewha Medical Journal ; : 90-93, 2015.
Article in English | WPRIM | ID: wpr-37516

ABSTRACT

Stress-induced cardiomyopathy, so-called Takotsubo cardiomyopathy, has recently been reported in Japan. Stress-induced cardiomyopathy is characterized by transient left ventricular apical dysfunction and ballooning, with normal coronary angiographic findings. We describe a rare case of stress-induced cardiomyopathy associated with lung adenocarcinoma presenting as hyponatremia.


Subject(s)
Acute Coronary Syndrome , Adenocarcinoma , Carcinoma, Non-Small-Cell Lung , Cardiomyopathies , Hyponatremia , Inappropriate ADH Syndrome , Japan , Lung , Lung Neoplasms , Takotsubo Cardiomyopathy
13.
Clinical and Experimental Vaccine Research ; : 189-194, 2015.
Article in English | WPRIM | ID: wpr-22780

ABSTRACT

PURPOSE: A new rabies vaccine for animals, including raccoon dogs, in Korea is needed to eradicate rabies infection. In this study, we constructed two recombinant adenoviruses expressing the glycoprotein or nucleoprotein of the rabies virus (RABV). We then investigated the safety and immunogenicity of these strains in raccoon dogs, depending on inoculation route. MATERIALS AND METHODS: Recombinant adenoviruses expressing the glycoprotein (Ad-0910G) or nucleoprotein (Ad-0910N) of rabies were constructed in 293A cells using an adenoviral system. One-year-old raccoon dogs underwent intramuscular (IM) inoculation or oral administration of the recombinant Ad-0910G and Ad-0910N. Clinical symptoms were observed and virus-neutralizing antibodies (VNA) against RABV were measured at 0, 2, 4, and 6 weeks after the immunization. Raccoons were considered positive if VNA titers were > or = 0.1 IU/mL. RESULTS: Raccoon dogs inoculated with the combined Ad-0910G and Ad-0910N virus via the IM route did not exhibit any clinical sign of rabies during the observation period. All raccoon dogs (n = 7) immunized IM had high VNA titers, ranging from 0.17 to 41.6 IU/mL at 2 weeks after inoculation, but 70% (7/10) of raccoon dogs administered viruses via the oral route responded by 6 weeks after administration against RABV. CONCLUSION: Raccoon dogs inoculated with Ad-0910G and Ad-0910N viruses showed no adverse effects. Immunization with the combined Ad-0910G and Ad-0910N strains may play an important role in inducing VNA against RABV in raccoon dogs.


Subject(s)
Animals , Adenoviridae , Administration, Oral , Antibodies , Glycoproteins , Immunization , Korea , Nucleoproteins , Rabies Vaccines , Rabies virus , Rabies , Raccoon Dogs , Raccoons
14.
Tuberculosis and Respiratory Diseases ; : 385-389, 2015.
Article in English | WPRIM | ID: wpr-20102

ABSTRACT

Amyloidosis is defined as the presence of extra-cellular deposits of an insoluble fibrillar protein, amyloid. The pulmonary involvement of amyloidosis is usually classified as tracheobronchial, parenchymal nodular, or diffuse alveolar septal. A single nodular lesion can mimic various conditions, including malignancy, pulmonary tuberculosis, and fungal infection. To date, only one case of nodular pulmonary amyloidosis has been reported in Korea, a case involving multiple nodular lesions. Here, we report and discuss the case of a patient having single nodular amyloidosis.


Subject(s)
Humans , Amyloid , Amyloidosis , Korea , Tuberculosis, Pulmonary
15.
Chonnam Medical Journal ; : 97-101, 2015.
Article in English | WPRIM | ID: wpr-121243

ABSTRACT

This study aimed to identify factors that affect the size of benign thyroid nodules and to predict nodule size by using a newly developed model. Because most thyroid nodules are benign, they are commonly only monitored. Only a few studies have evaluated the natural progression or regression of benign thyroid nodules. Large-scale studies on the subject are nonexistent. Between January 2001 and December 2011, our study subjects were selected from among 1,564 patients with benign thyroid nodules (2,469 nodules) in a retrospective analysis. We measured nodule size and volume and attempted to predict nodule size by using a newly developed model. Nodules were considered to have increased in size if the total volume increased by >15%. Nodules that increased in size over time required a longer follow-up period than nodules that decreased in size. The proportion of females and the cystic proportion of the nodules were relatively high in our study sample. For thyroid nodules that increased in size, we analyzed potential predictive factors. Larger nodule volume, extended follow-up period, and high cystic proportion were positively associated with increased nodule size. According to the model we developed in our study, the nodules in the group with an increase in size grew at an approximate rate of 0.034 cm3 per year when controlled for other factors. Percutaneous ethanol injection or radiofrequency ablation is performed for cosmetic purposes and proper functioning if or when nodules reach a certain size. The model used in our study may offer helpful insight in determining an optimal treatment schedule for benign thyroid nodules.


Subject(s)
Female , Humans , Ablation Techniques , Appointments and Schedules , Catheter Ablation , Ethanol , Follow-Up Studies , Retrospective Studies , Thyroid Gland , Thyroid Nodule
16.
Korean Journal of Pancreas and Biliary Tract ; : 146-150, 2015.
Article in Korean | WPRIM | ID: wpr-28886

ABSTRACT

Direct peroral cholangioscopy (POC) which permits direct visualization of the biliary tree has recently gained widespread clinical use for diagnosis and treatment of various pancreatobiliary diseases. But, there is currently little reliable data on evaluating the complications of POC. POC is associated with complications such as pancreatitis, cholangitis, hemorrhage, rarely air embolism, and ductal perforation. The incidence of complication during POC is 2.9-12%. However, pneumoperitoneum due to intrahepatic bile duct perforation after POC has not yet been reported in Korea. We report a case of pneumoperitoneum after POC which has been successfully managed with endoscopic nasobiliary drainage and antibiotics.


Subject(s)
Anti-Bacterial Agents , Bile Ducts, Intrahepatic , Biliary Tract , Cholangitis , Diagnosis , Drainage , Embolism, Air , Hemorrhage , Incidence , Korea , Pancreatitis , Pneumoperitoneum
17.
The Korean Journal of Parasitology ; : 737-743, 2015.
Article in English | WPRIM | ID: wpr-91229

ABSTRACT

In order to examine the prevalence of Cryptosporidium infection in wild rodents and insectivores of South Korea and to assess their potential role as a source of human cryptosporidiosis, a total of 199 wild rodents and insectivore specimens were collected from 10 regions of South Korea and screened for Cryptosporidium infection over a period of 2 years (2012-2013). A nested-PCR amplification of Cryptosporidium oocyst wall protein (COWP) gene fragment revealed an overall prevalence of 34.2% (68/199). The sequence analysis of 18S rRNA gene locus of Cryptosporidium was performed from the fecal and cecum samples that tested positive by COWP amplification PCR. As a result, we identified 4 species/genotypes; chipmunk genotype I, cervine genotype I, C. muris, and a new genotype which is closely related to the bear genotype. The new genotype isolated from 12 Apodemus agrarius and 2 Apodemus chejuensis was not previously identified as known species or genotype, and therefore, it is supposed to be a novel genotype. In addition, the host spectrum of Cryptosporidium was extended to A. agrarius and Crosidura lasiura, which had not been reported before. In this study, we found that the Korean wild rodents and insectivores were infected with various Cryptosporidium spp. with large intra-genotypic variationa, indicating that they may function as potential reservoirs transmitting zoonotic Cryptosporidium to livestock and humans.


Subject(s)
Animals , Animals, Wild/parasitology , Cryptosporidiosis/parasitology , Cryptosporidium/classification , Feces/parasitology , Genotype , Eulipotyphla/parasitology , Molecular Sequence Data , Murinae , Phylogeny , Republic of Korea , Rodent Diseases/parasitology
18.
Clinical and Experimental Vaccine Research ; : 107-113, 2015.
Article in English | WPRIM | ID: wpr-203144

ABSTRACT

PURPOSE: New rabies vaccine bait for both pets and raccoon dogs residing in Korea is needed to eradicate rabies infection among animals. In this study, we constructed a recombinant rabies virus (RABV), the ERAG3G strain, using a reverse genetics system. Then we investigated the efficacy of this strain in mice after oral administration and the safety of this strain in cats after intramuscular administration. MATERIALS AND METHODS: The ERAG3G strain was rescued in BHK/T7-9 cells using the full-length genome mutated at the amino acid position 333 of the glycoprotein gene of RABV and helper plasmids. Four-week-old mice underwent one or two oral administrations of the ERAG3G strain and were challenged with the highly virulent RABV strain CVSN2c 14 days after the second administration. Clinical symptoms were observed and body weights were measured every day after the challenge. RESULTS: All mice showed complete protection against virulent RABV. In addition, cats intramuscularly inoculated with the ERAG3G strain showed high antibody titers ranging from 2.62 to 23.9 IU/mL at 28-day postinoculation. CONCLUSION: The oral immunization of the ERAG3G strain plays an important role in conferring complete protection in mice, and intramuscular inoculation of the ERAG3G strain induces the formation of anti-rabies neutralizing antibody in cats.


Subject(s)
Animals , Cats , Mice , Administration, Oral , Antibodies, Neutralizing , Body Weight , Genome , Glycoproteins , Immunization , Korea , Plasmids , Rabies , Rabies Vaccines , Rabies virus , Raccoon Dogs , Reverse Genetics
19.
Chonnam Medical Journal ; : 97-101, 2015.
Article in English | WPRIM | ID: wpr-788310

ABSTRACT

This study aimed to identify factors that affect the size of benign thyroid nodules and to predict nodule size by using a newly developed model. Because most thyroid nodules are benign, they are commonly only monitored. Only a few studies have evaluated the natural progression or regression of benign thyroid nodules. Large-scale studies on the subject are nonexistent. Between January 2001 and December 2011, our study subjects were selected from among 1,564 patients with benign thyroid nodules (2,469 nodules) in a retrospective analysis. We measured nodule size and volume and attempted to predict nodule size by using a newly developed model. Nodules were considered to have increased in size if the total volume increased by >15%. Nodules that increased in size over time required a longer follow-up period than nodules that decreased in size. The proportion of females and the cystic proportion of the nodules were relatively high in our study sample. For thyroid nodules that increased in size, we analyzed potential predictive factors. Larger nodule volume, extended follow-up period, and high cystic proportion were positively associated with increased nodule size. According to the model we developed in our study, the nodules in the group with an increase in size grew at an approximate rate of 0.034 cm3 per year when controlled for other factors. Percutaneous ethanol injection or radiofrequency ablation is performed for cosmetic purposes and proper functioning if or when nodules reach a certain size. The model used in our study may offer helpful insight in determining an optimal treatment schedule for benign thyroid nodules.


Subject(s)
Female , Humans , Ablation Techniques , Appointments and Schedules , Catheter Ablation , Ethanol , Follow-Up Studies , Retrospective Studies , Thyroid Gland , Thyroid Nodule
20.
International Journal of Thyroidology ; : 183-186, 2015.
Article in English | WPRIM | ID: wpr-103839

ABSTRACT

BACKGROUND AND OBJECTIVES: Radiofrequency ablation has recently been used for the treatment of benign thyroid nodules, with outstanding results. However, in most studies, the procedure was usually performed by a radiologist or surgeon. This study aimed to evaluate the efficacy and safety of radiofrequency ablation for nodules >2 cm performed by an endocrinologist with several years of experience performing fine-needle aspiration cytology. MATERIALS AND METHODS: This study was a cross-sectional analysis of 111 patients who received radiofrequency ablation between April 2010 and July 2013. A total of 73 patients with 75 nodules >2 cm in diameter with at least 6 months of follow-up examinations were included. RESULTS: The mean follow-up period was 11.5 months. The mean nodule volume decreased from 17.0+/-15.3 mL preoperatively to 6.0+/-8.5 mL postoperatively, with a mean volume reduction of 69.7%. There were no major complications, and only 1 patient (1.3%) presented with a minor complication (hemorrhaging of the thyroid parenchyma). CONCLUSION: Radiofrequency ablation is a safe method for reducing benign thyroid nodules, and is not associated with any major complications.


Subject(s)
Humans , Biopsy, Fine-Needle , Catheter Ablation , Cross-Sectional Studies , Follow-Up Studies , Thyroid Gland , Thyroid Nodule
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