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1.
Article in English | WPRIM | ID: wpr-49968

ABSTRACT

It was found to be the same case with the published article.

3.
Article in Korean | WPRIM | ID: wpr-114744

ABSTRACT

PURPOSE: To evaluate and compare the accuracy of magnetic resonance imaging (MRI) and ultrasound (US) for detection and estimation of invasion depth of colorectal carcinoma (CRC) by correlation with histopathologic findings in vitro, and to find out the best MR pulse sequence for accurate delineation of tumor from surrounding normal tissue. MATERIALS AND METHODS: Resected specimens of CRC from 45 patients were examined about tumor detectability and invasion depth of US using high frequency (5-17 MHz) linear transducer in a tube filled with normal saline and MRI in a 8-channel quadrate head coil. The institutional review board approved this study and informed consent was waived. MRI with seven pulse sequences of in- and out-of-phases gradient echo T1 weighted images, fast spin echo T2 weighted image and its fat suppression image, fast imaging employing steady-state acquisition (FIESTA) and its fat suppression image, and diffusion weighted image (DWI) were performed. In each case, both imaging findings of MRI and US were evaluated independently for detection and estimation of invasion depth of tumor by consensus of two radiologists and were compared about diagnostic accuracy according to the histopathologic findings as reference standard. Seven MR pulse sequences were evaluated on the point of accurate delineation of tumor from surrounding normal tissue in each specimen. RESULTS: In specimens of CRC, both imaging modalities of MRI (91.1%) and US (86.7%) showed relatively high diagnostic accuracy to detect tumor and evaluate invasion depth of tumor. In early CRC, diagnostic accuracy of US was 87.5% and that of MRI was 75.0%. There was no statistically significant difference between two imaging modalities (p > 0.05). The best pulse sequence among seven MR sequences for accurate delineation of tumor from surrounding normal tissue in each specimen of CRC was fast spin echo T2 weighted image. CONCLUSION: MRI and US show relatively high diagnostic accuracy to detect tumor and evaluate invasion depth of resected specimen of CRC. The most excellent pulse sequence of MRI for accurate delineation of tumor from surrounding normal tissue in CRC is fast spin echo T2 weighted image.


Subject(s)
Colorectal Neoplasms , Consensus , Diffusion , Ethics Committees, Research , Head , Humans , Informed Consent , Magnetic Resonance Imaging , Transducers
4.
Annals of Dermatology ; : 22-25, 2012.
Article in English | WPRIM | ID: wpr-122682

ABSTRACT

BACKGROUND: The use of intravenous contrast media (CM) has increased for the diagnosis of several diseases. The newly developed low osmolar nonionic contrast agents cause significantly decreased adverse reactions than the higher osmolar ones. However, adverse reactions may still occur, ranging in severity from minor side effects to severe complications. However, there have been few reports about cutaneous adverse reactions (CARs) to nonionic monomer CM. OBJECTIVE: The purpose of this study was to evaluate clinical features of CAR to intravenous nonionic monomer CM. METHODS: A total 47,338 examinees underwent intravenous iodinated contrast-enhanced computed tomography scan using nonionic monomer CM. Among the adverse reactions to the CM, we divided them into cutaneous or noncutaneous and immediate ( or =1 hr) adverse reactions. RESULTS: Adverse reactions were noted in 62 cases out of the total 47,338 cases; 50 cases (80.7%) were categorized CARs. Among them, there were 24 male and 26 female patients. There was no significant difference between the sexes, and CARs occurred in all age groups. The highest occurrence was in the age range of 50~59 years. CARs included urticaria (78%), angioedema (10%), maculopapular rash (8%), erythema (2%), and pruritus without rash (2%). Immediate reactions were 92% (46 cases), while late reactions were 8% (4 cases). CONCLUSION: CARs to nonionic monomer CM accounted for most of the adverse reactions (80.7%) and urticaria was the most common.


Subject(s)
Angioedema , Contrast Media , Erythema , Exanthema , Female , Humans , Korea , Male , Pruritus , Urticaria
5.
Article in English | WPRIM | ID: wpr-178527

ABSTRACT

Acalculous hemorrhagic cholecystitis is a rare complication of acute cholecystitis and is associated with a high mortality rate. We present a case of acalculous hemorrhagic cholecystitis with hematoma in the gallbladder lumen, which was diagnosed using magnetic resonance imaging (MRI). The T1- & T2-weighted MRI revealed gallbladder distension with a hypointense intraluminal hematoma. The excellent tissue contrast provided by MRI is useful for detecting hematomas in the cases of hemorrhagic cholecystitis.


Subject(s)
Acalculous Cholecystitis , Cholecystitis , Cholecystitis, Acute , Gallbladder , Hematoma , Magnetic Resonance Imaging
6.
Article in Korean | WPRIM | ID: wpr-34138

ABSTRACT

PURPOSE: To evaluate and compare the diagnostic accuracy of MRI and ultrasound(US) for estimation of invasion depth of gastric carcinoma by correlation with histopathologic findings in vitro and to find out the best MR pulse sequence for detection and accurate delineation of tumor. MATERIALS AND METHODS: Resected specimen of total or subtotal gastrectomy from 53 patients with gastric carcinoma were done of imaging studies of MRI and US. And US was examined by using high frequency linear transducer for tumor invasion depth by a radiologist. In each case, both imaging findings of MRI and US were evaluated independently for tumor detection and invasion depth by consensus of two radiologists and were compared the diagnostic accuracy between two imaging modalities according to the histopathologic findings. MR imaging with five MR pulse sequences, spin echo T1 and in- and out-ofphase gradient echo T1 weighted images, FSE and SSFSE T2 weighted images, were performed. Five MR pulse sequences were evaluated and compared on the point of detection and accurate distinction of tumor from surrounding normal tissue. RESULTS: In EGC, diagnostic accuracy of US(77%) was superior than that of MRI(59%) but no statistically significant difference was noted between two imaging modalities(p=0.096). In AGC, both imaging modalities of MRIand US showed relatively high diagnostic accuracy as 97% and 84% respectively. Diagnostic accuracy of MRI was statistically better than that of US at the significant level(p<0.001). The best MR pulse sequence among five in each specimen was FSE T2WI(75.5%, 40/53) in both EGC and AGC. In AGC, FSE T2WI showed excellent imaging quality by showing very high ratio (93.5%, 29/31) of accurate delineation of tumor. CONCLUSION: MRI and US show relatively high diagnostic accuracy in the evaluation of tumor invasion depth of resected specimen in AGC. The most excellent pulse sequence of MRI for the evaluation of tumor invasion depth is FSE T2WI on the point of detection and accurate delineation of tumor in both EGC and AGC.


Subject(s)
Consensus , Gastrectomy , Humans , Transducers
7.
Article in Korean | WPRIM | ID: wpr-102530

ABSTRACT

Gastric schwannoma is a rare benign intramural tumor arising from the stomach, and it accounts for only 0.1% of all the different kinds of gastric neoplasms, and it's less than 4% of all the benign gastric tumors. This tumor is very difficult to differentiate from the other mesenchymal tumors by the clinical, endoscopic and radiologic findings. In this study, we demonstrate the appearance of this tumor on endoscopic ultrasound and contrast-enhanced abdomen CT. We also show the histopathologic findings of a surgically confirmed gastric schwannoma that was located in the proper muscle layer.


Subject(s)
Abdomen , Neurilemmoma , Stomach , Stomach Neoplasms , Ultrasonography
8.
Article in Korean | WPRIM | ID: wpr-102528

ABSTRACT

Gastrointestinal malignant fibrous histiocytomas (MFH) are very rare and only about 30 cases have been reported in the English literature, among which 20 cases were from colorectal MFHs. A small bowel MFH with intussusception has been the only reported case in the Korean medical literature. A 52-year-old male presented with complaints of recently developed and aggravated right upper abdominal pain. We present the CT appearance and the clinico-pathologic findings of his primary inflammatory malignant fibrous histiocytoma, which arose from the subserosal layer of the ascending colon with tumor infiltration in all the layers. The colon showed extensive hemorrhagic necrosis and repetitive multifocal microperforations with resultant panperitonitis.


Subject(s)
Abdominal Pain , Colon , Colon, Ascending , Histiocytoma , Histiocytoma, Malignant Fibrous , Humans , Intussusception , Male , Middle Aged , Necrosis
9.
Article in Korean | WPRIM | ID: wpr-110795

ABSTRACT

PURPOSE: One of the most serious complications of benign prostatic hyperplasia (BPH) is acute urinary retention (AUR). Up to now, many papers have evaluated the short term treatment of patients with AUR that is due to BPH. Therefore, we evaluated the long term follow-up of BPH patients with AUR. MATERIALS AND METHODS: 154 BPH patients with AUR were divided into two groups. One group was considered to be the failure cases of urethral catheter removal, and this group (55 patients) had undergone immediately transurethral resection of prostate (TURP). The other group was considered to be the successful cases of urethral catheter removal. The latter group was divided into 3 groups: the alpha-blocker group, the alpha-blocker with 5alpha- reductase inhibitor group and the suprapubic cystostomy with medical treatment group. We evaluated the long term follow-up of these groups and the changes of treatment for 1 month, 3 months, 6 months and 12 months. RESULTS: The mean volume of the prostate was 54.2ml. When the patients were admitted to the hospital due to AUR, 53% of the patients had previously experienced AUR, and the mean number of previous AUR episodes were 1.4 times. The initial management of AUR due to BPH was urethral catheter indwelling with medical treatment. If the catheter removal failed, TURP was perfomed (35%) and when successful, medical treatment was then done. CONCLUSIONS: The primary management of AUR due to BPH is urethral catheter indwelling with medical treatment (alpha-blocker). However, if the patients have a large size prostate, we should first consider hormone treatment (5alpha-reductase inhibitor) rather than surgical treatment. The management methods of some patients were changed during the follow-up. Therefore, when following up these cases, we should be careful to prevent the recurrence of AUR and to allow self-voiding.


Subject(s)
Acute Disease , Catheters , Cystostomy , Follow-Up Studies , Humans , Oxidoreductases , Prostate , Prostatic Hyperplasia , Recurrence , Transurethral Resection of Prostate , Urinary Catheters , Urinary Retention
10.
Article in Korean | WPRIM | ID: wpr-182334

ABSTRACT

OBJECTIVE: To evaluate the changes in mammographic density by different types of hormone replace therapy (HRT) in postmenopausal women. METHODS: A total of 150 postmenopausal women who received same HRT regimen for 1 year were classified as the four groups according to the regimen of HRT; 1) daily conjugated equine estrogen (CEE) 0.625 mg+medroxiprogesterone acetate (MPA) 2.5 mg (CEE/MPA-continuous, n=42), 2) daily CEE 0.625 mg+MPA 10 mg on days 1-12 (CEE/MPA-cyclic, n=28), 3) daily CEE 0.625 mg (CEE only, n=40), 4) daily tibolone 2.5 mg (Tibolone, n=40). And 40 women were allocated as control group. The changes in mammographic density in each group were compared with before and after HRT for 1 year. RESULTS: The increase in mammographic density after 1 year of HRT was significantly higher in CEE/MPA-continuous group and CEE/MPA-cyclic group compaired with control group (p<0.05), and was not observed in CEE only group and tibolone group. CONCLUSION: Our results suggest that greater increase of mammographic density in postmenopausal women was significantly associated with estrogen/progestin combination therapy.


Subject(s)
Estrogens , Female , Humans , Mammography
11.
Korean Journal of Medicine ; : S937-S941, 2004.
Article in Korean | WPRIM | ID: wpr-8793

ABSTRACT

Granular cell tumor is a relatively uncommon and usually benign neoplasm of the soft tissue. Most cases are benign, and only over 40 cases of malignant granular cell tumors were reported by the presence of metastases in the world literature. A 54-year-old woman with cough, mild exertional dyspnea and abnormal chest radiography was admitted to our hospital. Four years ago, the patient underwent a surgical excision of the mass at the left thigh. The lesion was diagnosed as a granular cell tumor. Chest and abdominal CT scans showed multiple variable sized pulmonary and hepatic nodules. Multiple osteoblastic and osteolytic bone lesions were also noted on chest and abdominal CT scans. Ultrasonography-guided biopsy of the pulmonary and hepatic nodule were done. The histologic examination revealed a tumor growing in nests and sheets. Tumor cells contained abundant eosinophilic granular cytoplasm which was PAS-positive and resistant to diastase digestion. After histologic examination, we diagnosed as a malignant granular cell tumor. We report a case of malignant granular cell tumor with multiple pulmonary, bone and hepatic metastases.


Subject(s)
Amylases , Biopsy , Cough , Cytoplasm , Digestion , Dyspnea , Eosinophils , Female , Granular Cell Tumor , Humans , Middle Aged , Neoplasm Metastasis , Osteoblasts , Radiography , Soft Tissue Neoplasms , Thigh , Thorax , Tomography, X-Ray Computed
12.
Article in Korean | WPRIM | ID: wpr-196384

ABSTRACT

A pancreatic pseudocyst with a mediastinal extension is a rare clinical entity. Intrathoracic symptoms such as dysphagia or dyspnea due to compression or associated pleural effusions are quite common. The pseudocysts transverse the diaphragm via the esophageal hiatus or aortic hiatus or by eroding directly through the diaphragm. Here, we report a case of a pancreatic pseudocyst with a mediastinal extension presenting as dysphagia and dyspnea. The diagnosis was confirmed by computerized axial tomography of the chest and abdomen. Usually, the proper management of a larger pseducocyst includes percutaneous or surgical internal drainage, but in this case the mediastinal components disappeared with conservative medical treatment.


Subject(s)
Abdomen , Cytochrome P-450 CYP1A1 , Deglutition Disorders , Diagnosis , Diaphragm , Drainage , Dyspnea , Mediastinum , Pancreatic Pseudocyst , Pleural Effusion , Thorax
13.
Article in Korean | WPRIM | ID: wpr-216090

ABSTRACT

PURPOSE: The purpose of this study was to determine the proton MR spectroscopic features of liver cirrhosis and the different proton MR spectroscopic features between liver cirrhosis and the normal human liver by comparing the two different conditions. MATERIALS AND METHODS: The investigation involved 30 cases of in-vivo proton MR spectra obtained from 15 patients with liver cirrhosis demonstrated on the basis of radiologic and clinical findings, and from 15 normal volunteers without a past or current history of liver disease. MR spectroscopy involved the use of a 1.5T GE Signa Horizon system (GE Medical Systems, Milwaukee, U.S.A.) with body coil. STEAM (STimulated Echo-Aquisition Mode) with 3000/30 msec of TR/TE was used for signal acquisition; patients were in the prone position and respiration was not interrupted. Cases were assigned to either the cirrhosis or normal group, and using the proton MR spectra of cases of in each group, peak changes occurring in lipids (at 1.3ppm), glutamate and glutamine (at 2.4 -2 .5ppm), phosphomonoesters (at 3.0 -3 .1ppm), and glycogen and glucose (at 3.4 -3 .9ppm) were evaluated. Mean and standard deviation of the ratio of glutamate + glutamine/lipids, phospho-monoesters/lipids, glycogen + glucose/lipids were calculated from the area of their peaks. The ratio of various metabolites to lipid content was compared between the normal and cirrhosis group. RESULTS: The main characteristic change in proton MR spectra in cases of liver cirrhosis compared with normal liver was decreased relative intensity of lipid peak. Mean and standard deviation of ratio of glutamate + g-lutamine/ lipids, phosphomonoesters/lipids, glycogen + glucose/lipids calculated from the area of their peaks of normal and cirrhotic liver were 0.0204 +/-0.0067 and 0.0693 +/-0.0371 (p<0.05), 0.0146 +/-0.0090 and 0.0881 +/-0.0276 (p<0.05), 0.0403 +/-0.0267 and 0.2325 +/-0.1071 (p<0.05), respectively. The other character-istic feature of proton MR spectra of liver cirrhosis was the peak detected at 3.9 - 4.1 ppm with unknown nature. Mean and standard deviation of area ratio of the unknown peak to lipid peak in proton MR spectra of liver cirrhosis was 0.1504 +/-0 . 0 3 5 5 . CONCLUSION: Proton MR spectra of liver cirrhosis revealed decreased intensity of lipid with statistical signifi-cance compared with that of normal liver, and peak at 3.9 -4.1 ppm with unknown nature. In conclusion, liver cirrhosis can be diagnosed non-invasively by the analysis of observed proton MR spectroscopic features.


Subject(s)
Fibrosis , Glucose , Glutamic Acid , Glutamine , Glycogen , Healthy Volunteers , Humans , Liver Cirrhosis , Liver Diseases , Liver , Magnetic Resonance Spectroscopy , Prone Position , Protons , Respiration , Steam
14.
Article in Korean | WPRIM | ID: wpr-28591

ABSTRACT

PURPOSE: To evaluate the patterns of hemodynamic changes caused by various pathologic liver conditions. MATERIALS & METHODS: Combined CT hepatic arteriography(CTHA) and CT arterial portography(CTAP), performed in 185 consecutive patients, including 150 with hepatocellular carcinoma, were retrospectively analysed. Of these patients, 48 showed various patterns of hemodynamic change. such change caused by occlusion, stenosis and/or cavernous transformation of the portal vein, by occlusion or stenosis of the hepatic artery, or by the presence of arterioportal(AP) shunt could be classified as follows : type 1, decreased or absent portal flow ; type 2,decreased or absent hepatic arterial flow ; type 3, AP shunt without portal tumor thrombus(PTT) ; and type 4, PTT with transvasal AP shunt, including the presence of cavernous transformation of the portal vein. RESULTS: Type I (n=20) showed hyperattenuation of both PTT and absent portal flow area on CTHA, and reciprocally consistent hypoattenuation on CTAP. Type II (n=6) showed a hypoattenuating area on CTHA, and isoattenuation or slightly hyperattenuation on CTAP. Type III (n=9) showed an oval or wedge-shaped hyperattenuating area on CTHA, anddefective perfusion at the same area on CTAP. In Type IV (n=13), both CTHA and CTAP showed variable findings, according to the amount of transvasal AP shunt, the location and extent of PTT, and/or cavernous transformation ofthe portal vein. CONCLUSION: Pattern analyses of hemodynamic changes on both CTHA and CTAP are helpful inclarifying the primary causes of hemodynamic changes in the liver.


Subject(s)
Angiography , Carcinoma, Hepatocellular , Constriction, Pathologic , Hemodynamics , Hepatic Artery , Humans , Liver , Perfusion , Portal Vein , Retrospective Studies
15.
Article in Korean | WPRIM | ID: wpr-92039

ABSTRACT

PURPOSE: To evaluate the role of CT in early detection, location, and extent of osteochondritis dissecans (OCD) of the elbow joint. MATERIALS AND METHODS: We reviewed surgically proved 27 cases of 22 patients with osteochondritis dissecans in elbow joint retrospectively. We compared simple x-ray(elbow AP & lateral) with CT on the basis of staging of OCD of talus by simple x-ray. RESULTS: The frequency of location was as follows:fourteen cases of capitellum, 5 cases of olecranon tip, 5 cases of medial epicondyle, 2 cases of trochlea, and 1 case of olecranon base. Among the 4 cases of normal finding on simple x-ray, CT showed 1 case each of stage I, II, III, and IV OCD and among the 8 cases of stage I on simple x-ray, CT showed 2 cases of stage I, 1 case of stage II, and 5 cases of stage III. Among the 3 cases of stage II on simple x-ray, CT showed 1 case of stage II and 2 cases of stage III. Among the 5 cases of stage III on simple x-ray, CT showed 1 case of stage II, 2 cases of stage III, and 2 cases of stage IV, but it was difficult to detect the presence or absence of attachment between the articular cartilage of mother bone and osteochondral fragment. CT was more accurate than simple x-ray in detection of loose body. CONCLUSION: CT might be an useful imaging modality in early diagnosis of OCD and evaluation of its anatomic location and extent in elbow joint.


Subject(s)
Cartilage, Articular , Early Diagnosis , Elbow Joint , Elbow , Humans , Mothers , Olecranon Process , Osteochondritis Dissecans , Osteochondritis , Retrospective Studies , Talus
16.
Article in Korean | WPRIM | ID: wpr-73879

ABSTRACT

PURPOSE: There is increasing awareness of the clinical importance of early detection and treatment of posterior cruciate ligament(PCL) injury. We evaluate the usefulness of Magnetic resonance(MR) imaging in the diagnosis of PCL injury. MATERIALS AND METHODS: We retrospectively analysed the MR images of 140 cases with clinically suspected knee injury. Arthroscopic or surgical correlation was available in 63 cases. We observed the finding and extent of PCL injury and other associated abnormalities. The frequency of anterior and posterior meniscofemoral ligament was evaluated. RESULTS: Eleven PCL injuries were observed, six midsubstance tears, two tibial attachment tears, two fernoral attachment tear, one laxity. The sensitivity, specificity and accuracy of MR imaging diagnosis are 100%, 98.1%, 98.4%. MR findings of PCL injury are discontinuity and focal mass formation, irregular increased signal intensity, detachment or redundancy of the ligament with avulsed bony fragment. In all cases of injured PCL, other associated abnormalities of adjacent structures were observed. Accessory anterior and posterior meniscofemoral ligaments were observed in 67.4%(87/129). CONCLUSION: MR imaging is useful in evaluation of presence or absence of PCL injury, accurate extent of PCL injury and other important associated abnormalities of adjacent structures.


Subject(s)
Diagnosis , Knee Injuries , Ligaments , Magnetic Resonance Imaging , Posterior Cruciate Ligament , Retrospective Studies , Sensitivity and Specificity
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