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Indian J Pathol Microbiol ; 2007 Oct; 50(4): 875-7
Article in English | IMSEAR | ID: sea-75426


Inflammatory myofibroblastic tumour formerly also known as inflammatory pseudotumour, was recognized initially in the lung and has been described in other visceral organs. It's occurrence in the subcutis is not well documented and its cytological appearance may be misinterpreted as malignant. This is the first case report of inflammatory myofibroblastic tumour of the subcutis in pediatric age group. A 12 year old female child presented with a subcutaneous swelling in the left anterior chest wall. FNA was performed and the cytological appearances were interpreted as malignant. Histopathology and immunohistochemistry revealed an inflammatory myofibroblastic tumour of the subcutis. FNA cytology is not very helpful in distinguishing inflammatory myofibroblastic tumour from malignant lesions especially soft tissue sarcomas. Awareness of it's occurrence in the subcutis is of importance for it's proper identification and treatment.

Biopsy, Fine-Needle , Child , Diagnosis, Differential , Female , Granuloma, Plasma Cell/diagnosis , Humans , Immunohistochemistry , Skin Neoplasms/diagnosis , Subcutaneous Tissue/pathology , Thoracic Wall/pathology
Indian J Pathol Microbiol ; 2007 Oct; 50(4): 877-80
Article in English | IMSEAR | ID: sea-75114


Primary cutaneous lymphoma designates a heterogenous group of disorders arising from skin T and B cells with no evidence of extra cutaneous disease at the time of diagnosis and six months thereafter. We report the cytomorphological features of a case of primary cutaneous lymphoma, B cell type in a 60 year old female presenting with multiple large bosselated red coloured swellings all over the scalp. Clinical examination revealed no other swelling or lymphadenopathy. On cytology a diagnosis of B-cell cutaneous lymphoid hyperplasia (B-CLH) was given, however cutaneous lymphoma could not be ruled out. On biopsy and immuno-histochemistry a diagnosis of primary cutaneous lymphoma B cell type was made. Patient was started on specific chemotherapy of lymphoma to which she responded completely. Here we highlight the cytomorphologic, histopathological and immunohistochemical features of this rare lesion with a particular emphasis on the diagnostic dilemma encountered on cytology.

Antineoplastic Agents/therapeutic use , Biopsy , Female , Humans , Immunohistochemistry , Lymphoma, B-Cell/drug therapy , Middle Aged , Scalp/pathology , Skin Neoplasms/drug therapy