Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add filters








Language
Year range
1.
Journal of Medical Postgraduates ; (12): 963-967, 2017.
Article in Chinese | WPRIM | ID: wpr-613038

ABSTRACT

Objective Different types of colon cancer have a big difference in their clinical features and prognosis.The article aimed to provide theoretical basis for the diagnosis and treatment of colon cancer patients by analyzing the differences of clinical features and survival rates between hereditary non-polyposis colorectal cancer (HNPCC) and sporadic colon cancer.Methods Retrospective analysis was made on 22 HNPCC cases and 105 cases of sporadic colon cancer in our hospital from January 2007 to January 2012 to get the clinical features and prognosis by comparative analysis.Results Compared with sporadic group, the early onset(under 40 years) (36.37% vs 9.52%), mucinous adenocarcinoma (59.09% vs 17.14%), low differentiation (45.45% vs 16.19%), TNM stage (III+IV) (54.55% vs 26.66%), lymph node metastasis (81.82% vs 57.14%), multiple primary carcinoma (36.36% vs 7.62%) and parenteral tumor (22.73% vs 5.71%) were higher in HNPCC group, but the 5 year survival rate was lower in HNPCC group, and there were significant differences between two groups(P0.05) between two groups.Multiple primary tumors were independent risk factors for survival in HNPCC group (P<0.05), lymph node metastasis and TNM stage were independent risk factors for survival sporadic group (P<0.05).Conclusion Compared with sporadic colon cancer, HNPCC is characterized by early onset, low differentiation, high incidence of multiple primary tumors and poor prognosis, which is of great importance to find HNPCC patients or suspicious HNPCC patients.

SELECTION OF CITATIONS
SEARCH DETAIL