Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 2 de 2
Filter
Add filters








Language
Year range
1.
Article in Chinese | WPRIM | ID: wpr-906536

ABSTRACT

Citri Reticulatae Semen is a traditional Chinese medicine in our country. By referring to the relevant literature and materials such as the works of ancient and modern materia medica, this paper summarizes the historical evolution of processing, quality analysis, pharmacological effects and other aspects of Citri Reticulatae Semen. The results showed that the processing methods of Citri Reticulatae Semen in the past dynasties mainly included stir-frying, processing with wine, baking with wine, etc. The modern stir-baking with salt solution was developed on the basis of the ancient stir-frying with green salt, most of the national and provincial processing standards contained crude and salt-processed products of Citri Reticulatae Semen. The properties and flavors of Citri Reticulatae Semen in the past dynasties were basically consistent with those in modern times. It is bitter in taste and neutral in nature. It belongs to the liver and kidney meridians and has the effects of regulating Qi, dispersing knots and relieving pain. Citri Reticulatae Semen contains limonins, fatty acids, proteins and mineral elements, etc. High performance liquid chromatography (HPLC), gas chromatography-mass spectrometry (GC-MS) and thin layer chromatography (TLC) were commonly used to detect and analyze Citri Reticulatae Semen. Citri Reticulatae Semen has anti-tumor, anti-inflammatory, analgesic and antibacterial activities, and processing can change the content of its chemical components to a certain extent. In a word, the current research about Citri Reticulatae Semen is not enough in-depth, it is necessary to further analyze the material basis of efficacy of Citri Reticulatae Semen and its processed products, explore the change law of chemical components before and after processing and the relationship between chemical composition and activity, and clarify the processing mechanism for providing scientific basis for its standardized processing, quality control and clinical rational use.

2.
Article in Chinese | WPRIM | ID: wpr-888014

ABSTRACT

The volatile oil of Curcumae Rhizoma has many active components,which are the key to the quality of Curcumae Rhizoma. Exploring the difference between volatile oil of different kinds of Curcumae Rhizoma facilitates the quality control and rational application of resources. In this study,GC-MS was applied to realize online qualitative and semi-quantitative analysis of the chemical composition spectrum of volatile oil from Curcuma wenyujin( CW),C. phaeocaulis( CP),and C. kwangsiensis( CK). Forty components were identified and their fingerprints were compared and evaluated. Hierarchical cluster analysis( HCA),principal component analysis( PCA),and orthogonal partial least squares discrimination analysis( OPLS-DA) were adopted to analyze the overall and outlier data. The results showed that the whole data could be divided into three kinds according to each analysis mode,and the volatile components of Curcumae Rhizoma vary greatly among species. PCA explored the difference between outliers and the mean value of the group and found that some volatile oils from CW may be greatly affected by the origin. By OPLS-DA,the samples from Zhejiang were able to gather,but those from Guizhou remained isolated,indicating the influence of growing environment on Curcumae Rhizoma metabolites. Based on VIP results combined with the heat map,characteristic volatile oil components of Curcumae Rhizoma from different varieties were screened out: curdione and linalool for CW; 2-undecanone for CP; humulene,γ-selinene,and zederone for CK. The GCMS method established in this study describes Curcumae Rhizoma samples comprehensively and accurately,and the characteristic components screened based on chemometrics can be used to distinguish Curcumae Rhizoma from different varieties and give them unique pharmacodynamic significance,which is fast,convenient,stable,and reliable and supports the rational application of Curcu-mae Rhizoma resources. It is found that the region of origin has great influence on CW,which is worthy of further study.


Subject(s)
Curcuma , Gas Chromatography-Mass Spectrometry , Oils, Volatile , Principal Component Analysis , Rhizome
SELECTION OF CITATIONS
SEARCH DETAIL