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Article in Chinese | WPRIM | ID: wpr-666866


Objective To investigate the therapeutic effect of Shugan Jieyu Capsules for the treatment of maintenance hemodialysis patients with insomnia. Methods Forty maintenance hemodialysis patients with insomnia were randomized into observation group and control group by random number table method,20 cases in each group. Patients of the two groups were given conventional maintenance hemodialysis and fundamental treatment for controlling blood pressure and glucose,regulating calcium-phosphorus metabolism,and relieving anemia. And additionally,the control group was treated with Estazolam Tablets orally,and the observation group was treated with Shugan Jieyu Capsules orally. By using Pittsburgh Sleep Quality Index(PSQI)scale,we investigated the changes of the quality of sleep in two groups before and after treatment,and evaluated the therapeutic effect. Results (1)After treatment,PSQI scores of the two groups were obviously decreased,and the difference was significant (P < 0.05 compared with those before treatment). The observation group had stronger effect on decreasing PSQI scores than the control group,the difference being significant(P < 0.05).(2)The total effective rate of the observation group was 90.0% and that of the control group was 75.0%, the difference being significant (P<0.05). (3)During the treatment,adverse reaction of morning dizziness or drug dependence was not shown. Conclusion Shugan Jieyu Capsules exert certain therapeutic effect for the treatment of maintenance hemodialysis patients with insomnia by improving the quality of sleep.