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Indian J Ophthalmol ; 2016 June; 64(6): 446-447
Article in English | IMSEAR | ID: sea-179314


Aim: The study was to analyze mean serum sodium and potassium levels in cataract patients and agematched individuals without cataract. Methods and Materials: It was a prospective case-control study. Individuals more than 50 years of age who attended our ophthalmic center in the year 2007-2010 were grouped into those having cataract and those without cataract. Mean serum sodium and potassium levels in the cataract groups were calculated and compared with the control group. Statistical software SPSS14 was used for statistical analysis. Results: Mean serum sodium levels in cataract group was 135.1 meqv/l and 133 meqv/l in the control group. Mean potassium was 3.96 meqv/l in the case study group and 3.97 meqv/l in controls. Mean sodium levels among cases were significantly higher than control group. No difference was seen in the PSC group and control. The difference in mean potassium among the two groups was statistically insignificant. Conclusion: Diets with high sodium contents are a risk factor for senile cataract formation and dietary modifications can possibly reduce the rate of progression cataract.

Indian J Ophthalmol ; 2010 Sept; 58(5): 415-417
Article in English | IMSEAR | ID: sea-136098


Colletotrichum graminicola is a medically important fungus belonging to the order Melanconiales under the class Coelomycetes. The members of the genus Colletotrichum are primarily plant pathogens which cause anthracnoses (fungal infection in plants). In the past few decades, they are progressively being implicated as etiological agents of subcutaneous hyalohyphomycoses and keratomycoses. Of the five medically important members in the genus Colletotrichum, keratitis due to Colletotrichum graminicola is rare. We diagnosed Colletotrichum graminicola keratitis in a 44-year-old man who presented with a non-healing corneal ulcer since three weeks. Positive smears and cultures from the corneal scrapings established the causative organism as C. graminicola. The patient was treated with a combination of oral ketoconazole and topical fluconazole and natamycin. Infection resolved over 10 weeks and antimicrobials were stopped. We describe the clinical presentation and treatment outcome of Colletotrichum graminicola keratitis.

Administration, Oral , Adult , Antifungal Agents/administration & dosage , Colletotrichum , Corneal Ulcer/microbiology , Drug Therapy, Combination , Fluconazole/administration & dosage , Humans , Keratitis/diagnosis , Keratitis/microbiology , Ketoconazole/administration & dosage , Male , Mycoses/diagnosis , Mycoses/drug therapy , Natamycin/administration & dosage , Treatment Outcome