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Article in Chinese | WPRIM | ID: wpr-906444


The historical evolution, fermentation technology and key links of Sojae Semen Praeparatum (SSP) were sorted out by consulting ancient books and modern literature, and the influencing factors and control methods of quality were analyzed and summarized in order to provide reference for the quality control of SSP. After analysis, it was found that in the fermentation process of SSP, fermentation strains, miscellaneous bacteria, temperature and humidity were all important factors affecting the quality of SSP. The condition control of "post fermentation" process has been paid more attention to in the past dynasties. In addition, the delicious SSP recognized in ancient times should be made from mold fermentation, and the breeding and application of fermented mold may be the key point to solve the quality problem of SSP. Therefore, based on the evaluation indexes of SSP in the past dynasties, it is of great significance to study and optimize the technological conditions such as strain, temperature and humidity in depth to improve the quality of SSP.

Article in Chinese | WPRIM | ID: wpr-879169


Based on the systematic retrieval and the reported components of Sojae Semen Nigrum and Sojae Semen Praeparatum, this study conducted in-depth analysis of conversion of components in the fermentation process, and discussed types and possible mec-hanisms of conversion of chemical components, so as to provide the basis for studying technology, medicinal ingredients and quality standards. According to the analysis, there is a certain degree of conversion of nutrients(like protein, sugar, lipid), bioactive substances(like isoflavones, saponins, γ-aminobutyric acid) and other substances(like nucleosides, melanoids, biamines, etc) in the process of fermentation.

Chromatography, High Pressure Liquid , Fermentation , Isoflavones/analysis , Semen/chemistry , Soybeans
Article in Chinese | WPRIM | ID: wpr-298479


<p><b>OBJECTIVE</b>To research the origin of Zibei Xiqi which included in Volume 3 of < Bencao Gangmu Shiyi > (A supplement to the compendium of materia medica).</p><p><b>METHOD</b>The origin of Zibei Xiqi was confirmed with textural, botanical characteristics research and drug name, therapeutic effects and so on.</p><p><b>RESULT</b>The origin of Zibei Xiqi was confirmed.</p><p><b>CONCLUSION</b>The Zibei Xiqi which is recorded in < Bencao Gangmu Shiyi > should be the immature herbs of Shuang Hudie [Tripterospermum chinense, Gentianaceae], and suggest to correct the original records of the drug name.</p>

Drug Therapy , Drugs, Chinese Herbal , Chemistry , Therapeutic Uses , Humans , Magnoliopsida , Chemistry , Materia Medica , Chemistry , Therapeutic Uses , Terminology as Topic
Article in Chinese | WPRIM | ID: wpr-264880


To investigate the historical origins of folk herbal medicine 'Xuelihua', the origin of 'Xuelihua' was confirmed by textural, botanical characteristics research, investigation of therapeutic effects and field survey. The 'Xuelihua' which was originally recorded in 'Bencao Gangmu Shiyi' (A Supplement to the Compendium of Materia Medica) should be 'Riben Shegencao' (Ophirrhiza japonica) of Rubiaceae family.

China , Drugs, Chinese Herbal , Classification , Pharmacology , Therapeutic Uses , Materia Medica , Medicine, Chinese Traditional , Rubiaceae , Classification
Article in Chinese | WPRIM | ID: wpr-351823


<p><b>OBJECTIVE</b>To isolate and determine the chemical constituents from Ranunculus japonicus.</p><p><b>METHOD</b>Compounds were isolated by column chromatography, and identified by MS, NMR data.</p><p><b>RESULT</b>Nine compounds were obtained andelucidated as scoparone (1), tricin (2), protocatechuic acid (3), luteolin (4), anemonin (5), scopoletin (6), 5-hydroxy-6, 7-dimethoxyflavone (7), 5-hydroxy-7, 8-dimethoxyflavone (8), ternatolide (9), respectively.</p><p><b>CONCLUSION</b>Compounds 1-9 were isolated from R. japonicus for the first time while compounds 7, 8 were separated from Ranunculus genus first time.</p>

Coumarins , Chemistry , Flavonoids , Chemistry , Plants, Medicinal , Chemistry , Ranunculus , Chemistry
Article in Chinese | WPRIM | ID: wpr-276632


<p><b>OBJECTIVE</b>To isolate and determine the chemical constituents from Ranunculus sceleratus.</p><p><b>METHOD</b>Six compounds were isolated and purified by extraction and different kinds of column chromatography. The structures were determined on the basis of extensive spectral analysis such as EI-MS, 1H-NMR, 13C-NMR, DEPT and NOEDS.</p><p><b>RESULT</b>The structures were elucidated as stigmasta-4-ene-3,6-dione I, stigmasterol II, isoscopoletin III, scoparone IV, protocatechuic aldehyde V and protocatechuic acid VI, respectively.</p><p><b>CONCLUSION</b>Compound I, III, IV, V and VI were isolated from R. genus for the first time.</p>

Benzaldehydes , Chemistry , Catechols , Chemistry , Cholestenones , Chemistry , Coumarins , Chemistry , Hydroxybenzoates , Chemistry , Plants, Medicinal , Chemistry , Ranunculus , Chemistry