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3.
An. bras. dermatol ; 96(1): 103-105, Jan.-Feb. 2021. graf
Article in English | LILACS | ID: biblio-1152796

ABSTRACT

Abstract Muir-Torre syndrome is a rare, autosomal dominant genodermatosis, characterized by sebaceous neoplasms and visceral carcinomas. The authors describe the case of a patient who, 16 years after the diagnosis of colon carcinoma, presented a verrucous plaque on the pubic region, histopathologically compatible with sebaceous adenoma. The need to investigate this syndrome is emphasized, especially in cases of sebaceous neoplasms located outside the head, face, and neck. Screening for neoplasms in these patients and their families is mandatory.


Subject(s)
Humans , Sebaceous Gland Neoplasms , Carcinoma , Adenoma , Colonic Neoplasms , Muir-Torre Syndrome
4.
An. bras. dermatol ; 95(5): 649-651, Sept.-Oct. 2020. graf
Article in English | ColecionaSUS, LILACS, ColecionaSUS | ID: biblio-1130936

ABSTRACT

Abstract The authors report a case of mobile and painful nodules on the bilateral plantar surface of a female patient referred by the rheumatology service, where she was being followed-up for rheumatoid arthritis. A nodule excision was performed for differential diagnosis and symptom relief; the histopathological analysis was compatible with a rheumatoid nodule. Although rheumatoid nodules are a common manifestation of rheumatoid arthritis, exclusive plantar involvement is seldom described in the literature.


Subject(s)
Humans , Female , Arthritis, Rheumatoid/diagnosis , Rheumatoid Nodule/diagnosis , Pain , Diagnosis, Differential
5.
An. bras. dermatol ; 95(4): 524-526, July-Aug. 2020. graf
Article in English | ColecionaSUS, LILACS, ColecionaSUS | ID: biblio-1130909

ABSTRACT

Abstract A 58-year-old female patient presented with a single-digit clubbing on the second finger of her right hand two years previously. After investigation with imaging and incisional biopsy, superficial acral fibromyxoma was diagnosed. A brief review on single-digit clubbing and its causes is presented, focusing on superficial acral fibromyxoma.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Aged , Young Adult , Hair Color , Turkey/epidemiology , Cross-Sectional Studies , Risk Factors , Alopecia , Middle Aged
6.
An. bras. dermatol ; 95(3): 347-350, May-June 2020. graf
Article in English | ColecionaSUS, LILACS, ColecionaSUS | ID: biblio-1130893

ABSTRACT

Abstract Intravascular histiocytosis is a rare condition characterized by the aggregate of histiocytes within dilated dermal vessels. The diagnosis is mainly histophatological and immunohistochemical. We describe a case of a 55 year-old female patient presenting erythematous/purple patches on the breasts, back and limbs. She previously presented ductal carcinoma in the right breast in 2006 which was treated with mastectomy and proceeded to silicone breast implant in 2009. Clinical hypothesis was telangiectatic metastatic carcinoma. Histopathology showed vascular ectasia, thrombosis and recanalization of upper dermis small vessels. On immunohistochemistry, intravascular cells were CD 68+ and negative for estrogen and progesterone receptors, CK7, EMA and AE1/AE3 and endothelial cells were CD64+, leading to the diagnosis of intravascular histiocytosis.


Subject(s)
Humans , Female , Silicones/adverse effects , Histiocytosis/etiology , Histiocytosis/pathology , Skin Diseases, Vascular/etiology , Skin Diseases, Vascular/pathology , Breast Implantation/adverse effects , Immunohistochemistry , Venous Thrombosis/etiology , Venous Thrombosis/pathology , Dilatation, Pathologic , Middle Aged
7.
An. bras. dermatol ; 95(2): 241-243, Mar.-Apr. 2020. graf
Article in English | ColecionaSUS, LILACS, ColecionaSUS | ID: biblio-1130855

ABSTRACT

Abstract Sporotrichosis is a deep mycosis of subacute or chronic evolution, caused by the dimorphic fungus of the genus Sporothrix. The treatment is carried out with antifungal orally or intravenously. Therapeutic success can be affected by several factors, such as altered gastrointestinal physiology by surgery. More and more patients are submitted to bariatric surgeries and the literature for the alterations of the absorption of medications in this context is very scarce. We intend to contribute to a better understanding with this case report of cutaneous-lymphatic sporotrichosis in a patient after bariatric surgery without response to itraconazole treatment, even at high doses.


Subject(s)
Humans , Female , Adult , Sporotrichosis/drug therapy , Itraconazole/therapeutic use , Bariatric Surgery/adverse effects , Antifungal Agents/therapeutic use , Sporotrichosis/pathology , Treatment Failure , Gastrointestinal Absorption
9.
An. bras. dermatol ; 95(1): 95-97, Jan.-Feb. 2020. graf
Article in English | LILACS | ID: biblio-1088711

ABSTRACT

Abstract The Borst-Jadassohn phenomenon is a morphological finding that consists of the presence of well-defined nests of cells located in the spiny stratum of an acanthotic epidermis. One of the neoplasms where this phenomenon is found is hidroacanthoma simplex. This neoplasm is considered the intraepidermal form of the eccrine poroma. Despite its benign nature, malignant transformations are reported. The present article reports a case of hidroacanthoma simplex and discusses the dermoscopy of this phenomenon.


Subject(s)
Humans , Female , Aged, 80 and over , Skin Neoplasms/pathology , Skin Neoplasms/diagnostic imaging , Acanthoma/pathology , Acanthoma/diagnostic imaging , Biopsy , Dermoscopy/methods , Epidermis/pathology , Epidermis/diagnostic imaging
12.
An. bras. dermatol ; 94(2): 230-232, Mar.-Apr. 2019. graf
Article in English | LILACS | ID: biblio-1001135

ABSTRACT

Abstract Eccrine porocarcinoma (EPC) is a rare malignant skin tumor. The dermoscopy of invasive EPC reveals focal presence of whitish-pink, structureless areas surrounded by pinkish-white halos. In an eccrine poroma (EP), such areas present diffuse distribution in the "frog- eggs" pattern. We reported an EPC in situ that presents a transitional dermoscopy pattern between EP and invasive EPC. We found a diffuse distribution; whitish-pink, structureless areas surrounded by pinkish-white halos; a central exulceration and a polymorphic vascular pattern.


Subject(s)
Humans , Female , Aged , Sweat Gland Neoplasms/diagnostic imaging , Poroma/diagnostic imaging , Eccrine Porocarcinoma/diagnostic imaging , Sweat Gland Neoplasms/pathology , Biopsy , Dermoscopy/methods , Diagnosis, Differential , Poroma/pathology , Eccrine Porocarcinoma/pathology , Leg
14.
An. bras. dermatol ; 93(6): 896-898, Nov.-Dec. 2018. graf
Article in English | LILACS | ID: biblio-973616

ABSTRACT

Abstract: Poroid neoplasms are benign epithelial proliferations with eccrine sweat gland differentiation. They are a challenging diagnosis because of the clinical heterogeneity, being able to mimic several malignant neoplasms. They are classified into classic poroma, hidroacanthoma simplex, dermal duct tumor and poroid hidradenoma. Association of histological subtypes occurs in more than 25% of cases. We report a case of a combined poroid neoplasia of classical poroma and poroid hidradenoma, reviewing its dermatoscopic features.


Subject(s)
Humans , Female , Aged , Sweat Gland Neoplasms/pathology , Sweat Gland Neoplasms/diagnostic imaging , Poroma/pathology , Poroma/diagnostic imaging , Dermoscopy
15.
An. bras. dermatol ; 93(6): 905-906, Nov.-Dec. 2018. graf
Article in English | LILACS | ID: biblio-973625

ABSTRACT

Abstract: We report a case of a 76-year-old patient with a history of recent weight loss and ulcerated umbilical nodular lesion. Initially, we considered the diagnostic hypothesis of Sister Mary Joseph's nodule. However, histopathological evaluation revealed that it was an ulcerated intradermal nevus. We perform a brief review of umbilical nodules.


Subject(s)
Humans , Male , Aged , Skin Neoplasms/diagnosis , Nevus, Intradermal/diagnosis , Sister Mary Joseph's Nodule/diagnosis , Skin Neoplasms/pathology , Nevus, Intradermal/pathology , Diagnosis, Differential
16.
An. bras. dermatol ; 93(4): 587-589, July-Aug. 2018. graf
Article in English | LILACS | ID: biblio-949931

ABSTRACT

Abstract: Granuloma faciale is a rare, chronic dermatologic disorder, which mainly affects the face. Recently, dermoscopy has been demonstrated as an important ancillary tool on the clinical diagnosis of facial dermatoses. We report two cases of granuloma faciale with yellow areas on dermoscopy that was not yet described in the literature, corresponding to abundant hemosiderin on histopathological examination.


Subject(s)
Humans , Male , Female , Adult , Aged , Facial Dermatoses/diagnosis , Granuloma/diagnosis , Dermoscopy
17.
An. bras. dermatol ; 93(4): 559-561, July-Aug. 2018. graf
Article in English | LILACS | ID: biblio-949911

ABSTRACT

Abstract: Acquired elastotic hemangioma is a hemangioma variant first described in 2002. It is characterized by being a benign, solitary, slow-growing lesion, that appears in adulthood and is associated with solar exposure. It is a rare hemangioma variant with few cases reported in the literature. We present a case of acquired elastotic hemangioma on the back of the right hand and forearm in a male adult. Acquired elastotic hemangioma is a benign vascular proliferation associated with solar exposure, usually assymptomatic. It affects adults between 59 and 65 years of age. Histopatologically it is characterized by proliferation of small vessels in the upper dermis that are disposed parallel to the epidermis, and significant solar elastosis. The treatment is surgical, with no relapses reported.


Subject(s)
Humans , Male , Middle Aged , Aged , Skin Neoplasms/pathology , Elastic Tissue/pathology , Hemangioma/pathology , Time Factors , Biopsy , Dermoscopy , Forearm
19.
An. bras. dermatol ; 93(1): 135-137, Jan.-Feb. 2018. graf
Article in English | LILACS | ID: biblio-887143

ABSTRACT

Abstract: Trichothiodystrophy refers to a heterogeneous group of rare genetic diseases that affects neuroectodermal-derived tissues with multisystem involvement. The hallmark of these syndromes is the deficiency of sulfur in hair matrix proteins, leading to short and brittle hair. Few cases of this rare disorder have been published. The authors report a case of trichothiodystrophy in a male infant with ichthyosis, photosensitivity, spastic paraparesis, short stature, and neurologic and psychomotor retardation. Diagnosis was based on clinical and microscopic features of hair samples.


Subject(s)
Humans , Male , Child, Preschool , Abnormalities, Multiple/diagnosis , Trichothiodystrophy Syndromes/diagnosis , Ichthyosis/diagnosis , Intellectual Disability/diagnosis , Photosensitivity Disorders/complications , Trichothiodystrophy Syndromes/complications , Ichthyosis/complications , Intellectual Disability/complications
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