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1.
Article in Chinese | WPRIM | ID: wpr-594573

ABSTRACT

Objective To study the clinical and pathological features of myofibrillar myopathy.Methods Clinical and pathological data of a patient with myofibrillar myopathy were anlysised retrospectively.Results The patient showed middle-aged onset,progressively proximal muscle weakness,mildly general muscle atrophy.Neurogenic changers were found in lower extremities on EMG.On mucle biopsy,cytoplasmic bodies presented in many muscle fibers in which disorganized myofibrillar networks and abnormal desmin aggregates were found,and rimmed vacuoles appeared in muscle fibers.Conclusions There is no specificity of clinical manifestation in myofibrillar myopathy.Cytoplasmic bodies,disorganized myofibrillar networks and abnormal desmin aggregates are the distinctively pathological features in myofibrillar myopathy.

2.
Article in Chinese | WPRIM | ID: wpr-544328

ABSTRACT

Somatostatin-containing neurons and nerve fibers in the commissural subnucleus of the nucleus tractus solitarii(NTS) of the rat were studied by means of munoelectron microscopy. The results showed that somatostatin-like immunoreactive positive neurons are medium or small cells, fusiform or elliptical. Somatostatin- like immunoreactive positive axons are unmyelinated,and mainly form passage or terminal synapses. Somatostatin-positive cell bodies themselves have not been obser- ved to form synapses with somatostatin-positive fibers,but their dendrites may receive innervation from immunoreactive-negative fibers by axo-dendritic synapses.

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