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1.
Article in Chinese | WPRIM | ID: wpr-905105

ABSTRACT

Objective:To explore the effect of Taiji Quan on the sleep quality of patients with chronic insomnia disorder (CID) and its mechanism. Methods:From January, 2015 to December, 2017, 31 patients with CID were enrolled in the sleep disorder clinic. Before and 24 weeks after Taiji Quan exercise, the Pittsburgh Sleep Quality Index (PSQI) was used to assess their sleep quality, the serum levels of tumor necrosis factor (TNF)-α, TNF-β, soluble tumor necrosis factor receptor (sTNF-R)1 and sTNF-R2 were detected with protein chip, and the correlation between the total score of PSQI and the serum levels of TNF-α, TNF-β, sTNF-R1 and sTNF-R2 were analyzed after exercise. Results:After Taiji Quan exercise, the scores of PSQI factors (subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, daytime dysfunction) and the total score of PSQI decreased (t > 4.080, P < 0.05). The serum levels of TNF-α and TNF-β decreased (t > 13.580, P < 0.01), however, the serum levels of sTNF-R1 and sTNF-R2 significantly increased (t > 160.189, P < 0.001). The serum levels of TNF-α and TNF-β were positively correlated with the total score of PSQI (r > 0.638, P < 0.001), while the serum levels of sTNF-R1 and sTNF-R2 were negatively correlated with the total score of PSQI (r > 0.532, P<0.001). Conclusion:Taiji Quan exercise could help to improve the sleep quality of patients with CID. The mechanism may be related to the decrease of the serum levels of TNF-α and TNF-β, and the increase of the serum levels of sTNF-R1 and sTNF-R2.

2.
Article in Chinese | WPRIM | ID: wpr-662510

ABSTRACT

Objective To explore the standardized management of high-value medical consumables during medical insurance management.Methods The definition of high-value medical consumables was introduced,and the problems of high-value medical consumables were analyzed in medical insurance management.The standardized management of highvalue medical consumables was discussed from the aspects of admission and purchase management,approval of high-value medical consumables,training on medical insurance policies,construction of high-value medical consumables examination and evaluation.Results Standardized management of high-value medical consumables contributed to slowing down the increase of per capita medical consumables,controlling the amount of medical consumables during hospitalization and increasing the ratio of domestic consumables.Conclusion All the medical facilities have to avoid irrational increase of highvalue medical consumables to utilize medical insurance fund reasonably with involvement of information platform,management regulation,approval flow as well as examination and evaluation system.

3.
Article in Chinese | WPRIM | ID: wpr-660185

ABSTRACT

Objective To explore the standardized management of high-value medical consumables during medical insurance management.Methods The definition of high-value medical consumables was introduced,and the problems of high-value medical consumables were analyzed in medical insurance management.The standardized management of highvalue medical consumables was discussed from the aspects of admission and purchase management,approval of high-value medical consumables,training on medical insurance policies,construction of high-value medical consumables examination and evaluation.Results Standardized management of high-value medical consumables contributed to slowing down the increase of per capita medical consumables,controlling the amount of medical consumables during hospitalization and increasing the ratio of domestic consumables.Conclusion All the medical facilities have to avoid irrational increase of highvalue medical consumables to utilize medical insurance fund reasonably with involvement of information platform,management regulation,approval flow as well as examination and evaluation system.

4.
Article in Chinese | WPRIM | ID: wpr-318280

ABSTRACT

<p><b>OBJECTIVE</b>To study the expression of plasma membrane Ca(2+)-ATPase isoform 2 (PMCA2) in spiral ganglion cell (SGC) from inner ear of newborn rats and further check PMCA2 splice variants at site A and C.</p><p><b>METHODS</b>Spiral ganglion tissues isolated from cochlea of newborn rats (P3-P4) were cultured and identified in vitro. The cochlea of newborn rats (P3-P4) were isolated and cut into frozen sections. The expression of PMCA2 was detected by immunofluorescence analyses. The SGC cultured in 4 wells of the 6-well culture plate were collected and the total RNA was extracted by Trizol and reverse transcribed to cDNA. The site A and C splice variants of PMCA2 were respectively checked by nested PCR and common PCR.</p><p><b>RESULTS</b>The SGC grew well with good refraction and showed positive immunoreactivity for neuronal marker NF-200. Strong green fluorescence could be seen in cytomembrane, cytoplasm and neuritis, as well showing SGC immunoreactivity for PMCA2 antibody. In the cochlear sections, the spiral ganglion tissues were strongly stained by PMCA2. PMCA2z was present at splice site A, but PMCA2b and PMCA2c were present at splice site C.</p><p><b>CONCLUSION</b>SGC from newborn rats strongly expresses PMCA2 and different splice variants are present at PMCA2 splice site A and C.</p>


Subject(s)
Animals , Female , Male , Plasma Membrane Calcium-Transporting ATPases , Metabolism , Protein Isoforms , Metabolism , RNA Splice Sites , Rats , Rats, Sprague-Dawley , Spiral Ganglion , Cell Biology , Metabolism
5.
Chinese Medical Journal ; (24): 1009-1014, 2009.
Article in English | WPRIM | ID: wpr-279791

ABSTRACT

<p><b>BACKGROUND</b>Significant progress has taken place over the past 50 years in the control of schistosomiasis japonica in China. However, the available data suggested that schistosomiasis has re-emerged shortly after the World Bank Loan Project which was conducted from 1992 to 2001. The national control program with a revised strategy to control schistosomiasis by using integrated measures has been implemented since 2005. In this study, we aimed to evaluate the effect of the national program on schistosomiasis control from 2005 to 2008.</p><p><b>METHODS</b>A retrospective study was carried out to analyze the epidemic patterns of acute infections with Schistosoma japonicum (S. japonicum), based on the number of acute cases annually collected from the web-based national communicable diseases reporting system from 2005 to 2008.</p><p><b>RESULTS</b>A total of 564, 207, 83 and 57 acute cases infected with S. japonicum were reported nationwide in 2005, 2006, 2007 and 2008, respectively, with an average annual reduction rate of 46.35% during last four years. Six outbreaks of acute infection with S. japonicum were reported in 2005 but none in the period of 2006 to 2008. All acute cases that were reported mainly came from the lake regions and became infected during the higher risk periods from the 27th to 43rd weeks of the year. Most of these cases are students (44.87%), farmers (31.51%) and fishermen (7.79%) who got the infection by water contact mainly through swimming (41.49%) and production activities (40.25%). With time, the proportion of imported cases among all acute cases increased due to more frequent movement of people that has occurred with a more mobile population.</p><p><b>CONCLUSIONS</b>The national control program on schistosomiasis aliened with the revised control strategy has been effectively brought into effect. However, there is still a significant risk of infection among students, farmers and fishermen living in the lake regions. Therefore, it is important to strengthen control measures among risk populations in the high risk areas of transmission, or the lake regions.</p>


Subject(s)
Acute Disease , Epidemiology , Animals , China , Epidemiology , Humans , Retrospective Studies , Schistosoma japonicum , Virulence , Schistosomiasis , Epidemiology
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