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Millets are excellent source of protein, minerals and dietary fibers, and therefore they can be supplemented in bakery products and plays a therapeutic role in human health. The present study is aimed at optimizing the level of pearl millet, finger millet and little millet flours for preparation of muffins. In the present study, pearl millet, finger millet and little millet flour was used at the rate of 10%, 20% and 10% respectively for treatment S1and for treatment S2, pearl millet, finger millet and little millet flour % was 10%, 15% and 15% respectively. For treatment S3, pearl millet, finger millet and little millet flour content was 10%, 10% and 20% respectively. Control samples were prepared using wheat flour in treatment S0. And after, the formulation of the samples, all the muffins were undertaken for proximate composition. The standardization of samples were done based on sensory scores. The results showed that samples of S1 treatment scored highest in color, texture and overall acceptability in organoleptic evaluation. Therefore, S1 sample was optimized and was further kept for storage studies. The moisture, fat, protein, carbohydrate and ash % was found to be 22.20, 18.21, 12.64, 45.23 and 1.94% respectively in muffin sample of S1 treatment which was considered as the standardized product. And after, the samples of S1 treatment were subjected to storage studies at room temperature, it was found that the muffin samples remained acceptable up to 60 days of storage as there was no microbial spoilage found on the product.
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Background: In advanced?stage epithelial ovarian cancer (EOC) standard of care is upfront debulking surgery (UDS) followed by adjuvant chemotherapy. Interval debulking surgery after neoadjuvant chemotherapy (NACT?IDS) is a reasonable alternative. Methods: This study was a retrospective review of patients of Stage III/IV EOC treated either by UDS or NACT?IDS between January 2016 and December 2018 to report the comparison of progression?free survival (PFS) and overall survival (OS) of patients with advanced?stage EOC treated with either UDS or NACT?IDS. Results: Out of 50 patients, 19 (38%) underwent UDS, and 31 (62%) received NACT. The mean follow?up duration was 27.7 months. No gross residual disease was achieved in 52.6% of the UDS group and in 70.4% of the NACT?IDS group. The median PFS of 20 and 30 months was observed in the UDS and NACT?IDS groups, respectively (log?rank P = 0.054). The median OS was 36 months in the NACT?IDS group and could not be reached in the UDS group (log?rank P = 0.329). Only residual disease was significantly associated with survival (hazards ratio 3.03, 95% confidence interval: 1.19�74) on multivariate Cox regression analysis. Conclusions: In advanced?stage EOC, the survival outcomes of NACT?IDS are comparable with those of UDS. Apart from the patient?specific parameters, the decision for UDS or NACT?IDS should take in account the expertise of the surgeon and the institutional capacity as a whole.
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Background: Patients with diabetes are at an increased risk of severe infection and mortality due to COVID-19. Absence of effective pharmacological treatments, vaccination remains one of the most effective means of controlling the pandemic. Our study aims to investigate the prevalence of COVID-19 infection among patients with diabetes mellitus and assess the coverage of COVID-19 vaccination among these patients. Methods: The patients were identified from a primary healthcare centre (PHC) based non-communicable disease (NCD) registry at PHC Najafgarh, New Delhi. A total of 480 patients were included in this study. The data was retrieved from NCD registry and vaccination status was confirmed from their vaccination certificates. Results: In our study 91.3% (438) of diabetic patients had received the first dose of COVID-19 vaccine and the coverage for second dose and third dose among these same patients are 84.6% and 27.3% respectively. Conclusions: Only a quarter of all the patients have received precautionary dose (3rd dose), and almost a tenth of all the patients have not even received a single dose of COVID-19 vaccine, the patients should be counselled and encouraged for vaccination. Also, it is recommended to take COVID-19 vaccination into consideration while taking the medical history of diabetics.
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A study was conducted on wheat (Triticum aestivum L.) in laboratory at Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya, Uttar Pradesh, during the 2019–20 for correlation and heritability analysis for seed quality under controlled conditions in wheat. In a wheat crop research, 30 germplasm were tested using three checks each for the parameters of seed weight, seed width, seed length, shoot length, root length, seedling length, seedling dry weight, germination (%), first count, final count, and vigour index-I and vigour index-II. In this study, the germplasm was assessed using parameters and the correlation coefficient. The vigour index-II demonstrated a very significant positive phenotypic connection with root length (0.828), final count (0.564), and first count (0.552), as well as a genotypically significant positive correlation with final count (1.165), root length (0.867), and first count (0.552). The high estimates (>15%) of phenotypic coefficient of variation (PCV) and genotypic coefficient of variation (GCV) were registered in the case of vigour index-I (PCV=17.36%, GCV=17.24%), shoot length (PCV=15.96%, GCV= 15.77%), seed width (PCV= 15.35%, GCV= 15.19%). The moderate estimate (10%) of PCV and GCV were recorded for root length (PCV=12.72%, GCV=12.56%), and seedling length (PCV= 11.46, GCV= 11.30).
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This study used 23 genotypes of bottle gourd—27 F1 hybrids, 12 Parents (9 lines, and 3 testers)—during two seasons (Y1 and Y2) and pooled analyses to analyze the correlations between fruit production per plant (Kg), growth, and economic features. The observations were evaluated based on qualities that are related to growth and yield. It was discovered that the fruit yield per plant had exhibited a significant and positive phenotypic correlation with the length of the male and female flowers' pedicels, the number of primary branches per plant, the length of the vine, the number of nodes per vine, the internodal length, the duration of picking, the length of the peduncle, the length of the fruit, the average fruit's circumference, the average fruit's weight, the number of fruits per plant. The highest positive direct effect on fruit yield per plant was exerted by number of fruit per plant followed by average fruit weight at phenotypic level. Whereas, higher negative direct effects exerted by days to first fruit harvest. The soil type of experimental site was sandy loam with average fertility level and pH in the range of 7.5-8.5
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@#Introduction: Anatomical femoral tunnel placement is critical for anterior cruciate ligament reconstruction (ACLR). Tunnel placement may vary with different surgical techniques. The aim of this study was to compare the accuracy of femoral tunnel placement between the Anteromedial (AM) and Anterolateral (AL) visualisation portals on post-operative CT scans among a cohort of ACLR patients. Materials and methods: This cross-sectional study was conducted from January 2018 to March 2020 after obtaining ethics clearance. Patients who went for arthroscopic ACLR in our institute were divided into an AM (group 1) and an AL (group 2) based on the visualisation portal for creating the femoral tunnel and a 3D CT scan was done. The femoral tunnel position was calculated in deep to shallow and high to low direction using the Bernard Hertel grid. Femoral tunnel angle was measured in the 2D coronal image. Statistical analysis was done with the data collected. Results: Fifty patients with an average age of 26.36 (18-55) years ±7.216 SD were enrolled in the study. In this study, the AM technique was significantly more accurate (p<0.01) than the AL technique in terms of femoral tunnel angle. Furthermore, the deep to the shallow position was significantly (p= 0.018) closer to normative values, as determined by the chi-square test. The chances of error in tunnel angle in femoral condyle are 2.6 times greater in the AL technique (minimal clinical difference). Conclusion: To conclude, in ACLR the anteromedial visualisation portal can facilitate accurate femoral tunnel placement compared to the anterolateral visualisation portal.
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Aim: The objective of the present study was to identify economically viable, profitable and resource efficient vegetables embedded rice-based cropping sequences under organic management for marginal and small farmers of Sikkim Himalayas, India.Methodology: Three-year fixed plot study was conducted to evaluate seven rice–based cropping sequences viz., rice–fallow (farmers’ practice), rice–fenugreek (leafy vegetable), rice–coriander (leaves), rice–radish, rice–broccoli, rice–potato and rice–vegetable pea were replicated four-times in a completely randomized block design. Results: Among the various rice – based cropping sequences, cultivation of rice–coriander (leaves) recorded higher production (67.3 kg ha-1 day-1), system productivity (24.6 t ha-1), relative economic efficiency (1040%) and net returns (376.1x103). However, rice-broccoli and rice–vegetable pea sequences recorded 8.6 and 4.4% higher B: C ratio, respectively, over the rice–coriander system. With regards to soil health, rice – vegetable pea cropping sequences resulted in maximum improvement in soil organic carbon (SOC) (1.26%), available soil N (415.2 kg ha-1), P (22.8 kg ha-1) and K (411.5 kg ha-1), soil microbial biomass carbon (SMBC) (344.7 µg MBC g-1 soil), dehydrogenase activity (DHA) (24.0 µg TPFg-1 soil h-1) and fluorescin di acetate (FDA) (38.8 µg FDAg-1 soil h-1) among the cropping sequences. Interpretation: Induction of vegetables in rice–fallow system under assured irrigation condition of Sikkim Himalayas, India not only enhances the farm productivity and profitability but also sustain the soil health on long term basis. Thus, rice-vegetable pea/coriander/broccoli based production systems under organic management hold great promises for sustaining livelihood of organic growers in Sikkim Himalayas over conventional rice– fallow system.
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Poland’s syndrome is a rare congenital anomaly consisting of a unilateral absence of the pectoralis major, ipsilateral muscle, hand anomaly and occasionally associated other malformations of the chest wall and breast. Many structural and functional abnormalities have been described in association with this syndrome. We report an incidentally diagnosed case in a 27-year-old male patient who presented to us with symbrachydactyly. In addition to this, anterior depression of 2nd, 3rd and 4th ribs and bifid (forked) 5th rib was present on radiological investigations. The body of sternum was short and deformed on the right side with absence of xiphoid process. All middle phalanges were absent on right hand. It is a rare variant of Poland’s syndrome.
Subject(s)
Adult , Fingers/abnormalities , Fingers/diagnostic imaging , Humans , Male , Muscular Diseases/complications , Pectoralis Muscles/abnormalities , Poland Syndrome/complications , Ribs/abnormalities , Syndactyly/complicationsABSTRACT
Three monospecific antibodies MSAb 1, MSAb 2 and MSAb 3 were raised in BALB/C mice against respective antigens. M. smegmatis whole cell lysate was first separated on SDS-PAGE and randomly chosen bands were cut and then used for immunization. Antibodies were collected as ascites by injecting mice with myeloma cell line P3X63 Ag 658.4. All the three antibodies showed high reactivity with denatured antigens compared to native. Different extent of cross-reactivity was observed as evident from ELISA. MSAb1 recognized a 75 kDa immunodominant antigen from M. smegmatis and 66 kDa from M. tuberculosis (H37Ra), respectively. An apparently similar molecular weight antigen shown to be present in M. tuberculosis (H37Ra) an avirulent strain and BCG, but not recognized by MSAb1. The 75 kDa antigen has a stimulatory effect on T-cell proliferation.