Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 67
Filter
1.
Journal of Korean Neuropsychiatric Association ; : 111-117, 2023.
Article in English | WPRIM | ID: wpr-1001253

ABSTRACT

Objectives@#An accurate and easy-to-identify form is needed for the early evaluation of suicidal ideation in high-risk patients. Therefore, this study examined the validity and reliability of a Korean version of the Ultra-Short Suicidal Ideation Scale (K-USSIS). @*Methods@#A total of 161 psychiatric university-affiliated general hospital patients completed the K-USSIS. The data were analyzed using correlation, internal consistency, and confirmatory factor analyses. @*Results@#First, the scale had good internal consistency with a Cronbach’s α of 0.94. Second, the confirmatory factor analysis demonstrated that the single-factor model had a reasonable fit (comparative fit index=0.99, Tucker–Lewis index=0.98, standardized root mean squared residual=0.01, and root mean square error of approximation=0.10). Finally, the convergent validity analysis revealed a significant positive correlation with depression, anxiety, and hopelessness. @*Conclusion@#The findings suggest that the K-USSIS has good psychometric properties and can serve as a valuable tool for screening for suicidal ideation to ensure early intervention in Korean psychiatric patients.

2.
Clinical Psychopharmacology and Neuroscience ; : 61-69, 2022.
Article in English | WPRIM | ID: wpr-924834

ABSTRACT

Objective@#Pharmacotherapy including mood stabilizers and antipsychotics are frequently used in bipolar disorder (BD); however, the lack of consensus regarding the definition of polypharmacy hinders conducting comparative studies across different settings and countries. Research on Asian Prescription Pattern (REAP) is the largest and the longest lasting international collaborative research in psychiatry in Asia. The objective of REAP BD was to investigate the prescription patterns of psychotropic medications across Asian countries. The rates of polypharmacy and psychotropic drug load were also analyzed. @*Methods@#The data collection was web-based. Prescription patterns were categorized as (1) mood stabilizer monotherapy: one mood stabilizer; (2) antipsychotic monotherapy: one antipsychotic; (3) simple polypharmacy: one mood stabilizer and one antipsychotic; and (4) complex polypharmacy: ≥ 2 mood stabilizers or/and antipsychotics. The psychotropic drug load in each patient was calculated using the defined daily dose method. @*Results@#Among 2003 patients with BD (52.1% female, 42.4 years) from 12 countries, 1,619 (80.8%) patients received mood stabilizers, 1,644 (82.14%) received antipsychotics, and 424 (21.2%) received antidepressants, with 14.7% mood stabilizer monotherapy, 13.4% antipsychotic monotherapy, 48.9% simple polypharmacy, 20.3% complex polypharmacy, and 2.6% other therapy. The average psychotropic drug load was 2.05 ± 1.40. Results varied widely between countries. @*Conclusion@#Over 70% of psychotropic regimens involved polypharmacy, which accords with the high prevalence of polypharmacy in BD under a permissive criterion (2 or more core psychotropic drugs) worldwide. Notably, ≥ 80% of our sample received antipsychotics, which may indicate an increasing trend in antipsychotic use for BD treatment.

3.
Psychiatry Investigation ; : 1058-1067, 2021.
Article in English | WPRIM | ID: wpr-918725

ABSTRACT

Objective@#Recently, rational polypharmacy approaches have been proposed, regardless of the lower risk and cost of monotherapy. Considering monotherapy as first-line treatment and polypharmacy as rational treatment, a balanced attitude toward polypharmacy is recommended. However, the high prevalence of polypharmacy led the Japanese government to establish a polypharmacy reduction policy. Based on this, the association between the policy and psychiatrists’ attitude toward polypharmacy has been under debate. @*Methods@#We developed an original questionnaire about Psychiatrists’ attitudes toward polypharmacy (PAP). We compared the PAP scores with the treatment decision-making in clinical case vignettes. Multiple regression analyses were performed to quantify associations of explanatory variables including policy factors and PAP scores. The anonymous questionnaires were administered to psychiatrists worldwide. @*Results@#The study included 347 psychiatrists from 34 countries. Decision-making toward polypharmacy was associated with high PAP scores. Multiple regression analysis revealed that low PAP scores were associated with the policy factor (β=-0.20, p=0.004). The culture in Korea was associated with high PAP scores (β=0.34, p<0.001), whereas the culture in India and Nepal were associated with low scores (β=-0.15, p=0.01, and β=-0.17, p=0.006, respectively). @*Conclusion@#Policy on polypharmacy may influence psychiatrists’ decision-making. Thus, policies considering rational polypharmacy should be established.

4.
Psychiatry Investigation ; : 48-58, 2021.
Article in English | WPRIM | ID: wpr-875374

ABSTRACT

Objective@#Network analysis can be used in terms of a novel psychopathological approach for depressive syndrome. We aimed to estimate the successive network structures of depressive symptoms in patients with depressive disorder using data from the Clinical Research Center for Depression study. @*Methods@#We enrolled 1,152 South Korean adult patients with depressive disorders who were beginning treatment for first-onset or recurrent depressive episodes. We examined the network structure of the severities of the items on the Hamilton Depression Rating Scale (HAMD) at baseline and at weeks 2, 12, 25, and 52. The node strength centrality of all the HAMD items at baseline and at week 2, 12, 25, and 52 in terms of network analysis. @*Results@#In the severity networks, the anxiety (psychic) item was the most centrally situated in the initial period (baseline and week 2), while loss of weight was the most centrally situated item in the later period (weeks 25 and 52). In addition, the number of strong edges (i.e., edges representing strong correlations) increased in the late period compared to the initial period. @*Conclusion@#Our findings support a period-specific and symptom-focused therapeutic approach that can provide complementary information to the unidimensional total HAMD score.

5.
Journal of Korean Neuropsychiatric Association ; : 86-95, 2021.
Article in English | WPRIM | ID: wpr-874786

ABSTRACT

Objectives@#We have been providing psychotherapy training for medical students enrolled in the course of ‘Clinical Practice.’ The aim of this study is to introduce the psychotherapy education developed in this process, conceptualize objective education methods, and check the impact of educational applications of psychotherapy for medical students. @*Methods@#Psychotherapy was applied to the medical students during their clerkship in psychiatry. 221 medical students participated in this program from 2017–2019, which consisted of 2–3 people in a group. One was in charge of clients, and the other was an observer. Their clerkship was based on psychodynamic psychotherapy, especially Taopsychotherapy. Before and after the practice, participants completed a self-reporting questionnaire about ego identity, self-concealment, and professional help-seeking attitudes. Statistical analysis using a two-way repeated measure analysis of variance was conducted. @*Results@#Participants learned of the nuclear feelings associated with the current problem and were surprised to find a connection with past experiences, but accepted the connection. Selfidentity decreased in the client role students (p=0.001), and professional help-seeking attitude increased in both client and observer role students (p=0.001). @*Conclusion@#In the general course of psychotherapy, patients are reminded of their first interpersonal relationships, like parents, and in the beginning, they only think of positive aspects under repressed emotions. However, they gradually recalled negative emotions. The above practical course featured this same pattern. As they recognized negative emotions that were repressed, self-identity decreased in client role students.

6.
Journal of Korean Neuropsychiatric Association ; : 277-284, 2020.
Article | WPRIM | ID: wpr-836013

ABSTRACT

Methods@#This study analyzed 350 Korean adults who were diagnosed with bipolar disorder and prescribed mood-stabilizing drugs. The patients were divided into two groups—patients who experienced cognitive side effects and those who did not experience cognitive side effects.We also compared the demographic and clinical characteristics between both groups. @*Results@#The number of patients with an untreated illness longer than 1 year was higher in the group of patients who experienced cognitive side effects compared to the group of patients who did not experience cognitive side effects. Further, the number of patients with manic symptoms at onset was higher in the group of patients who experienced cognitive side effects compared to the group of patients who did not experience cognitive side effects. In addition, the proportion of patients in remission was higher in the group of patients who experienced cognitive side effects compared to the group of patients who experienced no cognitive side effects. However, there was no significant difference regarding the type of mood stabilizer used between the groups. On the other hand, more people experienced cognitive side effects as the valproic acid dosage increased. @*Conclusion@#Our findings suggest that there are clinical and demographic differences between people who experienced cognitive side effects and those who did not experience cognitive side effects due to prescription of mood stabilizers.

7.
Journal of the Korean Society of Biological Therapies in Psychiatry ; (3): 56-64, 2020.
Article in English | WPRIM | ID: wpr-901137

ABSTRACT

Objectives@#:This study aimed to examine the validity scales of Minnesota Multiphasic Personality Inventory–2 Restructured Form (MMPI-2-RF) in Predicting premature termination and treatment duration in psychiatric outpatients. @*Methods@#:The MMPI–2 was administered to 202 patients with psychiatric medication, and its data converted to MMPI-2-RF was used for analysis. An independent t-test used to determine whether there was a difference in validity scales between premature termination group and treatment continued group. Then, logistic regression analysis was performed to determine the degree of effect on premature termination. Moreover, correlation analysis and multiple regression analysis were performed to confirm the relationship between treatment duration and validity scales. @*Results@#:The premature termination group showed higher score in variable response inconsistency (Vrin-r), adjustment validity (K-r) and lower score in infrequent responses (F-r) compared to the treatment continued groups. In logistic regression analysis, however, none of MMPI-2-RF validity scales predicted premature termination. Also, it was found that higher K-r score was associated with shorter treatment duration. @*Conclusion@#:The study showed that the MMPI-2-RF validity scales can predict whether to continue medication and treatment. Therefore, it is expected that more thorough studies of the attitudes toward treatment with respect to the validity scales provides the opportunity to find patients at high risk of premature treatment prior to medication and to strengthen their motivation for treatment, thereby leading to more effective and lasting treatment.

8.
Journal of the Korean Society of Biological Therapies in Psychiatry ; (3): 56-64, 2020.
Article in English | WPRIM | ID: wpr-893433

ABSTRACT

Objectives@#:This study aimed to examine the validity scales of Minnesota Multiphasic Personality Inventory–2 Restructured Form (MMPI-2-RF) in Predicting premature termination and treatment duration in psychiatric outpatients. @*Methods@#:The MMPI–2 was administered to 202 patients with psychiatric medication, and its data converted to MMPI-2-RF was used for analysis. An independent t-test used to determine whether there was a difference in validity scales between premature termination group and treatment continued group. Then, logistic regression analysis was performed to determine the degree of effect on premature termination. Moreover, correlation analysis and multiple regression analysis were performed to confirm the relationship between treatment duration and validity scales. @*Results@#:The premature termination group showed higher score in variable response inconsistency (Vrin-r), adjustment validity (K-r) and lower score in infrequent responses (F-r) compared to the treatment continued groups. In logistic regression analysis, however, none of MMPI-2-RF validity scales predicted premature termination. Also, it was found that higher K-r score was associated with shorter treatment duration. @*Conclusion@#:The study showed that the MMPI-2-RF validity scales can predict whether to continue medication and treatment. Therefore, it is expected that more thorough studies of the attitudes toward treatment with respect to the validity scales provides the opportunity to find patients at high risk of premature treatment prior to medication and to strengthen their motivation for treatment, thereby leading to more effective and lasting treatment.

9.
Journal of Korean Medical Science ; : 6-2020.
Article in English | WPRIM | ID: wpr-782490

ABSTRACT

No abstract available.


Subject(s)
Diagnostic and Statistical Manual of Mental Disorders , Korea
10.
Psychiatry Investigation ; : 459-463, 2019.
Article in English | WPRIM | ID: wpr-760946

ABSTRACT

Our study aimed to analyze the clinical characteristics and psychotropic prescription patterns of a history of suicide attempts in South Koreans with bipolar disorder (BD), by using only Korean data from the Research on Asian Psychotropic Prescription Pattern for Bipolar disorder. The patterns of clinical characteristics and psychotropic drug use were compared among 53 patients with a history of suicide attempts and 297 without this history; the potential effects of confounding variables were adjusted with binary logistic analyses for discrete variables and analyses of covariance for continuous variables. After adjusting the effects of age, sex, duration of illness, and enrollment as an outpatient, patients with a history of suicide attempts were characterized by a significantly more prevalent depressive episode, lower prevalent remission state, lower levels of hemoglobin, and more use of antidepressants, anxiolytics, and hypnotics compared to those without lifetime suicide attempt. The inability to plan goal-directed behavior may be an intervening factor in the relationship between suicide attempts and depression in BD. Relatively low hemoglobin levels can be associated with manic episodes in patients with a history of suicide attempts and the use of antidepressants, anxiolytics, or hypnotics can be associated with suicide attempts in BD patients.


Subject(s)
Humans , Anti-Anxiety Agents , Antidepressive Agents , Asian People , Bipolar Disorder , Depression , Drug Prescriptions , Hypnotics and Sedatives , Korea , Outpatients , Prescriptions , Suicide
11.
Psychiatry Investigation ; : 397-402, 2019.
Article in English | WPRIM | ID: wpr-760933

ABSTRACT

Based on Korean data from the Research on Asian Psychotropic Prescription Pattern for Bipolar Disorder, this study tried to present prescription patterns in biopolar disorder (BD) and its associated clinical features. Based on the information obtained from the study with structured questions, the tendency of prescription pattern was studied and analyzed. Polypharmacy was predominant, including simple polypharmacy in 51.1% and complex polypharmacy in 34.2% of patients. Subjects associated with simple or complex polypharmacy were significantly younger, had higher inpatient settings, a larger portion of onset with manic episode, a shorter duration of untreated illness, a shorter duration of current episode, were more overweight, used less antidepressants and used more anxiolytics. These findings can suggest higher polypharmacy rate in more severe BD and highlight the necessity of monitoring the weight of subjects with polypharmacy.


Subject(s)
Humans , Anti-Anxiety Agents , Antidepressive Agents , Asian People , Bipolar Disorder , Inpatients , Korea , Overweight , Polypharmacy , Prescriptions
12.
Psychiatry Investigation ; : 656-662, 2018.
Article in English | WPRIM | ID: wpr-715607

ABSTRACT

OBJECTIVE: Korean Neuropsychiatric Association changed the Korean name of schizophrenia from ‘Split-mind Disorder’ to ‘Attunement Disorder’ in 2012. This study assessed attitudes towards the renaming of schizophrenia among mental health practitioners (n=440), patients with schizophrenia and their guardians (n=396), and the university students (n=140) using self-administered questionnaires. METHODS: The questionnaire included items related to participants’ perception of the renaming of the disease, the nature of informing about the disease to confirm the effect of the name change. RESULTS: It was confirmed the notification rate of disease name by mental health practitioners was increased significantly after the renaming. Among patients and their guardians, 24.9% and 15.0%, respectively, perceived their own or the family member’s illness as ‘attunement disorder’. CONCLUSION: Patients and their guardians continue to display a low awareness about the name of the disease as ‘attunement disorder.’ However, mental health practitioners were found to be able to easily use the name ‘attunement disorder’ as a result of the increased notification rate of the new disease name.


Subject(s)
Humans , Korea , Mental Health , Schizophrenia
13.
Psychiatry Investigation ; : 1007-1008, 2018.
Article in English | WPRIM | ID: wpr-717816

ABSTRACT

The REAP-AP study recruited 3,746 patients with schizophrenia, in March and April 2016, from 71 centers in 15 Asian countries/territories namely Bangladesh, China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia, Myanmar, Pakistan, Singapore, Sri Lanka, Taiwan, Thailand and Vietnam. Our findings reveal a trend according to which high dose antipsychotic prescription is more prevalent in Eastern Asia (especially, Japan and Korea) than in other regions of Asia. This historical factor may be associated with our finding of an Eastern Asian preponderance of high dose antipsychotic prescription.


Subject(s)
Humans , Asia , Asian People , Bangladesh , China , Asia, Eastern , Hong Kong , India , Indonesia , Japan , Korea , Malaysia , Myanmar , Pakistan , Prescriptions , Schizophrenia , Singapore , Sri Lanka , Taiwan , Thailand , Vietnam
14.
Journal of Korean Medical Science ; : 1054-1055, 2017.
Article in English | WPRIM | ID: wpr-224182

ABSTRACT

No abstract available.

15.
Clinical Psychopharmacology and Neuroscience ; : 28-34, 2017.
Article in English | WPRIM | ID: wpr-222873

ABSTRACT

OBJECTIVE: This study was aimed at evaluating the diagnostic validity of the Korean version of the Clinically Useful Depression Outcome Scale (CUDOS) with varying follow-up in a typical clinical setting in multiple centers. METHODS: In total, 891 psychiatric outpatients were enrolled at the time of their intake appointment. Current diagnostic characteristics were examined using the Structured Clinical Interview for DSM-IV (41% major depressive disorder). The CUDOS was measured and compared with three clinician rating scales and four self-report scales. RESULTS: The CUDOS showed excellent results for internal consistency (Cronbach's α, 0.91), test-retest reliability (patients at intake, r=0.81; depressed patients in ongoing treatment, r=0.89), and convergent and discriminant validity (measures of depression, r=0.80; measures of anxiety and somatization, r=0.42). The CUDOS had a high ability to discriminate between different levels of depression severity based on the rating of Clinical Global Impression for depression severity and the diagnostic classification of major depression, minor depression, and non-depression. The ability of the CUDOS to identify patients with major depression was high (area under the receiver operating characteristic curve=0.867). A score of 20 as the optimal cutoff point was suggested when screening for major depression using the CUDOS (sensitivity=89.9%, specificity=69.5%). The CUDOS was sensitive to change after antidepressant treatment: patients with greater improvement showed a greater decrease in CUDOS scores (p<0.001). CONCLUSION: The results of this multi-site outpatient study found that the Korean version of the CUDOS is a very useful measurement for research and for clinical practice.


Subject(s)
Humans , Anxiety , Classification , Depression , Diagnostic and Statistical Manual of Mental Disorders , Follow-Up Studies , Mass Screening , Outpatients , Psychometrics , Reproducibility of Results , ROC Curve , Weights and Measures
16.
Psychiatry Investigation ; : 568-576, 2017.
Article in English | WPRIM | ID: wpr-123499

ABSTRACT

OBJECTIVE: The aim of this study was to validate the psychotic depression assessment scale (PDAS), which includes the six-item melancholia subscale from the Hamilton depression rating scale (HAMD-6) and the five-item psychosis subscale from the brief psychiatric rating scale (BPRS-5). Data from the Clinical Research Center for Depression (CRESCEND) study, which is a 52-week naturalistic trial, were analyzed. METHODS: Fifty-two patients with psychotic depression from the CRESCEND study met our inclusion criteria. The patients underwent the following psychometric assessments: the PDAS, including HAMD-6 and BPRS-5, the clinical global impression scales, the HAMD, the positive symptom subscale, and the negative symptom subscale. Assessments were performed at the baseline and then at weeks 1, 2, 4, 8, 12, 24, and 52. Spearman correlation analyses were used to assess the clinical validity and responsiveness of the PDAS. RESULTS: The clinical validity and responsiveness of the PDAS, including HAMD-6 and BPRS-5, were acceptable, with the exception of the clinical responsiveness of the PDAS for positive symptoms and the clinical responsiveness of BPRS-5 for negative symptoms. CONCLUSION: The clinical relevance of the PDAS has been confirmed and this clinical validation will enhance its clinical utility and availability.


Subject(s)
Humans , Brief Psychiatric Rating Scale , Depression , Depressive Disorder , Psychometrics , Psychotic Disorders , Weights and Measures
17.
Yonsei Medical Journal ; : 784-789, 2016.
Article in English | WPRIM | ID: wpr-205735

ABSTRACT

We aimed to examine the potential relationship between season of birth (SOB) and clinical characteristics in Korean patients with unipolar non-psychotic major depressive disorder (MDD). Using data from the Clinical Research Center for Depression (CRESCEND) study in South Korea, 891 MDD patients were divided into two groups, those born in spring/summer (n=457) and those born in autumn/winter (n=434). Measurement tools comprising the Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, Brief Psychiatric Rating Scale, Scale for Suicidal Ideation, Clinical Global Impression of severity, Social and Occupation Functional Assessment Scale, WHO Quality of Life assessment instrument-abbreviated version, Alcohol Use Disorder Identification Test, and Temperament and Character Inventory were used to evaluate depression, anxiety, overall symptoms, suicidal ideation, global severity, social function, quality of life, drinking, and temperament and character, respectively. Using independent t-tests for continuous variables and χ2 tests for discrete variables, the clinical characteristics of the two groups were compared. MDD patients born in spring/summer were on average younger at onset of first depressive episode (t=2.084, p=0.038), had greater loss of concentration (χ2=4.589, p=0.032), and were more self-directed (t=2.256, p=0.025) than those born in autumn/winter. Clinically, there was a trend for the MDD patients born in spring/summer to display the contradictory characteristics of more severe clinical course and less illness burden; this may have been partly due to a paradoxical effect of the 5-HT system.


Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Age of Onset , Alcohol Drinking , Bipolar Disorder/diagnosis , Character , Cost of Illness , Depression , Depressive Disorder, Major/diagnosis , Personality Inventory/statistics & numerical data , Quality of Life , Republic of Korea/epidemiology , Seasons , Temperament
18.
Journal of Korean Medical Science ; : 617-622, 2016.
Article in English | WPRIM | ID: wpr-58418

ABSTRACT

Our study aimed to establish the relationship between the number of depressive symptoms and the clinical characteristics of major depressive disorder (MDD). This would enable us to predict the clinical significance of the number of depressive symptoms in MDD patients. Using data from the Clinical Research Center for Depression (CRESCEND) study in Korea, 853 patients with DSM-IV MDD were recruited. The baseline and clinical characteristics of groups with different numbers of depressive symptoms were compared using the χ2 test for discrete variables and covariance (ANCOVA) for continuous variables. In addition, the scores of these groups on the measurement tools were compared by ANCOVA after adjusting the potential effects of confounding variables. After adjusting the effects of monthly income and history of depression, a larger number of depressive symptoms indicated higher overall severity of depression (F [4, 756] = 21.458, P < 0.001) and higher levels of depressive symptoms (F [4, 767] = 19.145, P < 0.001), anxiety symptoms (F [4, 765] = 12.890, P < 0.001) and suicidal ideation (F [4, 653] = 6.970, P < 0.001). It also indicated lower levels of social function (F [4, 760] = 13.343, P < 0.001), and quality of life (F [4, 656] = 11.975, P < 0.001). However, there were no significant differences in alcohol consumption (F [4, 656] = 11.975, P < 0.001). The number of depressive symptoms can be used as an index of greater illness burden in clinical psychiatry.


Subject(s)
Adult , Female , Humans , Male , Middle Aged , Alcohol Drinking , Analysis of Variance , Antidepressive Agents/therapeutic use , Anxiety , Depression , Depressive Disorder, Major/drug therapy , Quality of Life , Severity of Illness Index , Sex Factors , Suicidal Ideation
19.
Journal of Korean Neuropsychiatric Association ; : 41-50, 2016.
Article in Korean | WPRIM | ID: wpr-20867

ABSTRACT

OBJECTIVES: The purposes of this study are to examine the sociodemographic factors that increase the prevalence of insomnia, as well as to identify the relationship between the prevalence of insomnia and health conditions by navigating through the prevalence rates of insomnia in two different geographical regions with different socioeconomic structures. METHODS: A survey was conducted targeting 937 residents of Guri-si and Yangpyeong-gun in Gyeonggi Province, Korea. The Insomnia Severity Index was used to verify whether a respondent was experiencing insomnia. The Abbreviated Self-Rated Korean version of the Mini-International Neuropsychiatric Interview was used in diagnosis of mental diseases. Chi-square test was performed to determine the unique relationship between sociodemographic characteristics and the prevalence of insomnia. Multivariate logistic regression analysis was performed to examine the association of prevalence of insomnia with categorized relevant factors. RESULTS: The overall prevalence rate of insomnia for all respondents was 9.26%. The prevalence rate for Yangpyeong-gun was 11.75%, marking a significantly higher figure compared with the prevalence rate for Guri-si, which was 6.87%. Advanced age, female, other marital statuses than married, lower education, lower income, non-existence of private health insurance, and unemployment were risk factors for insomnia. The prevalence of insomnia showed strong association with physical and mental conditions, particularly with mental disorders, urologic diseases, and risk of injury from fall. CONCLUSION: The prevalence rates of insomnia in those two surveyed regions showed a meaningful difference even after controlling for sociodemographic characteristics. These findings suggest that such regional differences merits further attention and additional nationwide epidemiologic studies are needed.


Subject(s)
Female , Humans , Surveys and Questionnaires , Diagnosis , Education , Epidemiologic Studies , Insurance, Health , Korea , Logistic Models , Marital Status , Mental Disorders , Mental Health , Prevalence , Risk Factors , Sleep Initiation and Maintenance Disorders , Unemployment , Urologic Diseases
20.
Clinical Psychopharmacology and Neuroscience ; : 256-262, 2015.
Article in English | WPRIM | ID: wpr-209629

ABSTRACT

OBJECTIVE: To test whether there are gender differences in the clinical characteristics of patients with psychotic depression (PD). METHODS: Using data from the Clinical Research Center for Depression (CRESCEND) study in South Korea, we tested for potential gender differences in clinical characteristics among 53 patients with PD. The Psychotic Depression Assessment Scale (PDAS) and other psychometric scales were used to evaluate various clinical features of the study subjects. Independent t-tests were performed for normally distributed variables, Mann-Whitney U-tests for non-normally distributed variables, and chi2 tests for discrete variables. In addition, to exclude the effects of confounding variables, we carried out an analysis of covariance (ANCOVA) for the normally distributed variables and binary logistic regression analyses for discrete variables, after adjusting the effects of marital status. RESULTS: We identified more prevalent suicidal ideation (adjusted odds ratio [aOR]=10.316, p=0.036) and hallucinatory behavior (aOR=8.332, p=0.016), as well as more severe anxiety symptoms (degrees of freedom [df]=1, F=6.123, p=0.017), and poorer social and occupational functioning (df=1, F=6.265, p=0.016) in the male patients compared to the female patients. CONCLUSION: Our findings suggest that in South Korean patients with PD, suicidal ideation, hallucinatory behavior, and anxiety is more pronounced among males than females. This should be taken into consideration in clinical practice.


Subject(s)
Female , Humans , Male , Anxiety , Cost of Illness , Depression , Freedom , Korea , Logistic Models , Marital Status , Odds Ratio , Psychometrics , Suicidal Ideation , Weights and Measures
SELECTION OF CITATIONS
SEARCH DETAIL