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1.
Article in English | WPRIM | ID: wpr-922353

ABSTRACT

PURPOSE@#To retrospectively analyze the clinical outcomes of meniscus repair with simultaneous anterior cruciate ligament (ACL) reconstruction and explore the causes of failure of meniscus repair.@*METHODS@#From May 2013 to July 2018, the clinical data of 165 patients who were treated with meniscus surgery and simultaneous ACL reconstruction, including 69 cases of meniscus repair (repair group) and 96 cases of partial meniscectomy (partial meniscectomy group) were retrospectively analyzed. The exclusion criteria were as follows: (1) ACL rupture associated with fracture, collateral ligament injury, or complex ligament injury; (2) a history of knee surgery; or (3) a significant degree of osteoarthritis. The 69 patients in the repair group were divided into the non-failure group (62 cases) and the failure group (7 cases) depending on the repair effect. Postoperative outcomes of the repair group and the partial meniscectomy group were compared. General conditions and postoperative outcomes of the failure group and the non-failure group were compared. During the median follow-up period of 28 months (range, 4 - 65 months) after the second arthroscopy, postoperative outcomes of seven patients in the failure group were summarized. SPSS 25.0 statistical software was used for statistical analysis. A p value less than 0.05 was considered statistically significant.@*RESULTS@#Seven patients in the failure group who underwent the second arthroscopy were followed up for (30 ± 17.4) months and their postoperative outcomes were summarized. Compared with the partial meniscectomy group, the International Knee Documentation Committee scores of patients in the repair group improved significantly (p = 0.031). Compared with the non-failure group, more patients in the failure group were younger than 24 years (p = 0.030). The median follow-up period was 39.5 months. All patients recovered well after subsequent partial meniscectomy and relieved clinical symptoms. Visual analog scale scores decreased significantly (p = 0.026), and the International Knee Documentation Committee and Lysholm scores improved significantly (p = 0.046 for both).@*CONCLUSION@#The failure rate of meniscus repair in this study was 10.1% (7/69), all of which were medial meniscus tears. However, the surgical outcomes of ACL reconstruction were not affected, and there might be a role for graft protection. Therefore, meniscus retears can be successful treated by performing subsequent partial meniscectomy in patients with repair failure.


Subject(s)
Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Reconstruction , Humans , Menisci, Tibial/surgery , Meniscus , Retrospective Studies
2.
Article in Chinese | WPRIM | ID: wpr-774603

ABSTRACT

Nine compounds were isolated from chloroform fraction of Houttuynia cordata,and the isolates were identified as follows:( S)-5,6,6 a,7-tetrahydro-2,10-dimethoxy-4 H-dibenzo [DE,G] quinoline-1,9-diol( 1),( +)-isoboldine β-N-oxide( 2),liriotulipiferine( 3),telitoxinone( 4),isoboldine( 5),(-)-clovane-2β,9α-diol( 6),benzoic acid( 7),acantrifoside E( 8),and dibutyl phthalate( 9). Among them,compound 1 was new,and compounds 2-9 were reported from this species for the first time.


Subject(s)
Chloroform , Drugs, Chinese Herbal , Chemistry , Houttuynia , Chemistry , Phytochemicals , Plant Extracts , Chemistry
3.
Article in English | WPRIM | ID: wpr-771645

ABSTRACT

PURPOSE@#To evaluate the clinical outcome in patients who received anterior cruciate ligament (ACL) reconstruction via anteromedial portal with or without posterior wall blowout.@*METHODS@#Twenty patients with ruptured ACL, who have received ACL reconstruction via anteromedial portal between Apr 2012 and Oct 2013 were enrolled. According to the conditions of posterior wall, the patients were divided into 2 groups: posterior wall blowout group (10 patients) and posterior wall intact group (10 patients). The median follow up time were 63 (range 19-75) months and 60.5 (range 25-64) months in the 2 groups respectively. The clinical outcome was evaluated by knee joint physical examination, magnetic resonance imaging (MRI), the International Knee Documentation Committee (IKDC) 2000 subjective score, Lysholm score, Tenger score, difference of thigh circumference, KT-2000 and Biodex isokinetic dynamometer system.@*RESULTS@#No significant differences were found in terms of the IKDC score, Lysholm score, Tegner score, Lachman test positive rate or Pivot Shift test positive rate between the two groups. In KT-2000 and Biodex isokinetic dynamometer tests, the difference of muscle strength between affected knees and unaffected knees in posterior wall blowout group was not significant less than that of posterior wall intact group (p > 0.05). In addition, there is no statistical difference between the two groups in signal/noise quotient (SNQ) of the graft (p > 0.05) in post operative MRI.@*CONCLUSION@#Blowout of posterior wall in ACL reconstruction via anteromedial portal does not affect the clinical outcome as long as reliable fixation is taken intraoperatively.


Subject(s)
Adolescent , Adult , Anterior Cruciate Ligament , Pathology , General Surgery , Anterior Cruciate Ligament Injuries , Diagnosis , Pathology , Rehabilitation , General Surgery , Female , Follow-Up Studies , Humans , Male , Middle Aged , Orthopedic Procedures , Methods , Reconstructive Surgical Procedures , Methods , Retrospective Studies , Time Factors , Treatment Outcome , Young Adult
4.
Article in Chinese | WPRIM | ID: wpr-695911

ABSTRACT

Objective To observe the clinical efficacy of herb-partitioned moxibustion (HPM) at umbilicus in treating chronic prostatitis due to kidney-qi insufficiency. Method Sixty patients with chronic prostatitis due to kidney-qi insufficiency were randomized into a treatment group and a control group, 30 cases each. The treatment group was intervened by HPM, and the control group was treated with oral medication. The two groups were evaluated by using the National Health Institute-Chronic Prostatitis Symptom Index (NIH-CPSI) and the count of white blood cell of expressed prostatic secretion (EPS-WBC) before and after the intervention, and the clinical efficacies of the two groups were compared. Result The total effective rate was 90.0% in the treatment group versus 75.9% in the control group, and the between-group difference was statistically significant (P<0.05). The NIH-CPSI component scores were significantly changed in both groups after the treatment (P<0.01). There were no significant differences in the component scores of NIH-CPSI between the two groups after the treatment (P>0.05). The EPS-WBC count changed significantly in both groups after the treatment (P<0.01). After the intervention, the EPS-WBC count in the treatment group was significantly different from that in the control group (P<0.05). Conclusion HPM at umbilicus is an effective method in treating chronic prostatitis due to kidney-qi insufficiency.

5.
Article in Chinese | WPRIM | ID: wpr-236093

ABSTRACT

To investigate the effect and the mechanism of puerarin in attenuating PM2.5-induced human umbilical vein endothelial cells (EA.hy926) injury, the samples of fine particulate matter (PM2.5) were collected and made into suspension. Different concentrations of PM2.5 (0,20, 200, 400 mg•L⁻¹) were used to contaminate EA.hy926 cells for 24 h. The cells survival rate was detected by MTT assay; cells apoptosis of EA.hy926cells was detected by flow cytometry; the protein levels of p-ERK1/2, Bax and Bcl-2 were detected by Western blot; the contents of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), malonaldehyde (MDA), and the activities of superoxide dismutase (SOD) and lactic dehydrogenase (LDH) were measured by ELISA. Puerarin at different concentrations (10, 50, 100 μmol•L⁻¹) or a specific inhibitor of ERK1/2 pathway PD98059 (20 μmol•L-1) was added into the EA.hy926 cells to observe the intervention effect and mechanism of puerarin. Compared with the control group, PM2.5 reduced the cells survival rate, up-regulatedp-ERK1/2 protein level and Bax/Bcl-2 ratio in a dose dependent manner to promote apoptosis; increased the contents of TNF-α, IL-6 and MDA, the activity of LDH, but decreased SOD activity in the EA.hy926 cells (P<0.05). Compared with PM2.5 group, puerarin increased the cells survival rate, down-regulated p-ERK1/2 protein level and Bax/Bcl-2 ratio in a dose dependent manner to inhibit the apoptosis; decreased the contents of TNF-α, IL-6 and MDA, the activity of LDH, but increased SOD activity in the EA.hy926 cells (P<0.05). The results indicated that puerarin could attenuate PM2.5-induced EA.hy926 cells injury via the inhibition of ERK1/2 pathway.

6.
Chinese Journal of Surgery ; (12): 888-891, 2009.
Article in Chinese | WPRIM | ID: wpr-280575

ABSTRACT

<p><b>OBJECTIVE</b>To compare open and arthroscopic methods for treatment of recalcitrant lateral epicondylitis.</p><p><b>METHODS</b>A prospective trial of 26 patients (28 elbows) with recalcitrant lateral epicondylitis were treated between May 2006 and September 2008. The mean duration of conservative care was 23. 0 months (4 - 60 months). The mean follow-up was 17.4 months (4 - 32 months). The patients were randomized divided into two groups, 13 elbows with an open Nirschl procedure and 15 with an arthroscopic Nirschl procedure. All patients had pre- and post-operative assessment using VAS (visual analog scale) scores, Mayo 12 points elbow scores, time of return to work or sports, satisfaction, and so on.</p><p><b>RESULTS</b>There were no significant differences in VAS scores at rest and activities of daily living, time of return to work or sports and satisfaction between the two groups. But there was a statistically significant difference in VAS scores at work and sports and Mayo 12 points elbow scores between the two groups. 100% of the patients had excellent or good results in the open group and 93.3% in arthroscopic group. There were no severe complications in this series.</p><p><b>CONCLUSIONS</b>Both open and arthroscopic Nirschl procedures are valid and reliable treatments for patients with refractory lateral epicondylitis. The patients in the open group have a better function in the return-to work and sports postoperatively than the arthroscopic group.</p>


Subject(s)
Adult , Arthroscopy , Female , Follow-Up Studies , Humans , Male , Middle Aged , Orthopedic Procedures , Methods , Prospective Studies , Tennis Elbow , General Surgery , Treatment Outcome
7.
Chinese Journal of Surgery ; (12): 650-653, 2008.
Article in Chinese | WPRIM | ID: wpr-245528

ABSTRACT

<p><b>OBJECTIVE</b>To analyze the management principle of revision after anterior cruciate ligament (ACL) reconstruction and the factors contributing to its result.</p><p><b>METHODS</b>The data of 12 patients who received revision after ACL reconstructions from November 2001 to July 2006 were studied retrospectively. The indication of the operation, the management during the procedure and the clinical results were analyzed.</p><p><b>RESULTS</b>All the patients had pathological instability after primary ACL reconstructions. In this group, 2 cases received primary bone transplantation. The other 10 cases received primary ACL revision. Among them, 4 cases were reconstructed with STG obtained from the same lateral, 4 cases were obtained from the opposite lateral, 1 case was reconstructed with bone-patellar tendon-bone (B-PT-B) obtained from the same lateral, and 1 case was reconstructed with iliotibial tractus. One year later, the mean side-to-side difference of KT-2000 examination were 1.6 mm and 3.1 mm at 90 degrees and 30 degrees. The mean IKDC, Lysholm and Tegner scores were 72.8, 78.3 and 4.9.</p><p><b>CONCLUSIONS</b>The functional results and objective stability could be obtained through revision ACL reconstruction. However, outcomes are less favorable than those with primary reconstructions, which might be related to the factors including deficiency of previous surgery and impact of revision procedure.</p>


Subject(s)
Adolescent , Adult , Anterior Cruciate Ligament , General Surgery , Arthroscopy , Female , Follow-Up Studies , Humans , Male , Orthopedic Procedures , Methods , Treatment Outcome
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