ABSTRACT
Based on the formation of the evaluation, we conducted the reform of occupational health and occupational medicine teaching. The contents of the reform include the training of teachers, reintegrat-ing the practice contents, adopting the diversified teaching methods, and strengthening the network curricula and examination question bank construction, etc. And a formative evaluation index system was constructed, including the usual performance, experimental operation, occupational health survey, re-search design, PBL teaching, teaching effectiveness, self and mutual evaluation, a total of 7 first level evaluation indicators and 17 second level evaluation index. Finally, through the self-made questionnaire, the students in the experi-mental class of teaching reform were investigated, and the overall satisfaction rate was 91.9%.
ABSTRACT
<p><b>OBJECTIVE</b>To study the effects of intragastric administration of formaldehyde on lipid peroxidation in mice.</p><p><b>METHODS</b>Thirty ICR mice were randomly divided into 3 groups: one control group and two experimental groups. The mice were given formaldehyde (the dose is 0, 5 and 20 mg/kg body weight respectively) through intragastric administration once a day for 5 days , and then they were killed. The activities of SOD and the contents of MDA in liver were measured.</p><p><b>RESULTS</b>The activities of SOD in the 20 mg/kg body weight group were significantly lower than the control group (P < 0.05), and the contents of MDA in the 20 mg/kg body weight group were significantly higher than the control group (P < 0.05), and the liver organ coefficient in the 20 mg/kg body weight group is higher than the control group (P < 0.05).</p><p><b>CONCLUSION</b>A certain dose of formaldehyde can destroy the balance of lipid peroxidation in mice, the ability of antioxidation is reduced obviously, and the liver become compensatory hypertrophy.</p>